Silent volumetric multi-contrast 7 Tesla MRI of ocular tumors using Zero Echo Time imaging
Autoři:
Jan-Willem M. Beenakker aff001; Joep Wezel aff001; Jan Groen aff003; Andrew G. Webb aff001; Peter Börnert aff001
Působiště autorů:
Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands
aff001; Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands
aff002; Philips Healthcare, Best, the Netherlands
aff003; Philips Research Laboratories, Hamburg, Germany
aff004
Vyšlo v časopise:
PLoS ONE 14(9)
Kategorie:
Research Article
doi:
https://doi.org/10.1371/journal.pone.0222573
Souhrn
Magnetic Resonance Imaging (MRI) has become a valuable imaging modality in ophthalmology, especially for the diagnosis and treatment planning of patients with uveal melanoma, the most common primary intra-ocular tumor. We aim to develop and evaluate the value of silent Zero Echo Time (ZTE) MRI to image patients with ocular tumors at 7Tesla. Therefore, ZTE and different types of magnetization-prepared ZTE (FLAIR, SPIR, T2 and Saturation recovery), have been developed. After an initial validation with 7 healthy subjects, nine patients with an eye tumor have been evaluated. The ZTE scans were compared to their Cartesian equivalent in terms of contrast, motion-sensitivity, diagnostic quality and patient comfort. All volunteers and especially the patients reported a more comfortable experience during the ZTE scans, which had at least a 10 dB lower sound pressure. The image contrast in the native ZTE was poor, but in the different magnetization-prepared ZTE, the eye lens, cornea and retina were clearly discriminated. Overall the T2-prepared scan yielded the best contrast, especially between tumor and healthy tissue, and proved to be robust against eye motion. Although the intrinsic 3D nature of the ZTE-technique provides an accurate analysis of the tumor morphology, the quality of the ZTE-images is lower than their Cartesian equivalent. In conclusion, the quality of magnetization-prepared ZTE images is sufficient to assess the 3D tumor morphology, but insufficient for more detailed evaluations. As such this technique can be an option for patients who cannot comply with the sound-levels of Cartesian scans, but for other patients the conventional Cartesian scans offer a better image quality.
Klíčová slova:
Biology and life sciences – Anatomy – Head – Eye lens – Biochemistry – Lipids – Fats – Medicine and health sciences – Eyes – Ocular system – Ocular anatomy – Diagnostic medicine – Diagnostic radiology – Magnetic resonance imaging – Radiology and imaging – Ophthalmology – Ocular tumors – Research and analysis methods – Imaging techniques – Physical sciences – Physics – Acoustics – Sound pressure – Echoes
Zdroje
1. de Graaf P, Göricke S, Rodjan F, Galluzzi P, Maeder P, Castelijns JA, et al. Guidelines for imaging retinoblastoma: imaging principles and MRI standardization. Pediatr Radiol. Springer-Verlag; 2012;42(1):2–14. doi: 10.1007/s00247-011-2201-5 21850471
2. Diogo MC, Jager MJ, Ferreira TA. CT and MR Imaging in the Diagnosis of Scleritis. AJNR Am J Neuroradiol. 2016 Dec;37(12):2334–9. doi: 10.3174/ajnr.A4890 27444937
3. Beenakker J-WM, Shamonin DP, Webb AG, Luyten GPM, Stoel BC. Automated retinal topographic maps measured with magnetic resonance imaging. Invest Ophthalmol Vis Sci. 2015 Feb;56(2):1033–9. doi: 10.1167/iovs.14-15161 25593030
4. Beenakker J-WM, Ferreira TA, Soemarwoto KP, Genders SW, Teeuwisse WM, Webb AG, et al. Clinical evaluation of ultra-high-field MRI for three-dimensional visualisation of tumour size in uveal melanoma patients, with direct relevance to treatment planning. Magn Reson Mater Phy. 2016 Jun;29(3):571–7.
5. Graessl A, Muhle M, Schwerter M, Rieger J, Oezerdem C, Santoro D, et al. Ophthalmic magnetic resonance imaging at 7 T using a 6-channel transceiver radiofrequency coil array in healthy subjects and patients with intraocular masses. Invest Radiol. 2014 May;49(5):260–70. doi: 10.1097/RLI.0000000000000049 24651662
6. Berkowitz B, Detroit M, Canfield D, McDonald C, Ito Y, Tofts P, et al. Measuring the human retinal oxygenation response to a hyperoxic challenge using MRI: Eliminating blinking artifacts and demonstrating proof of concept. Magn Reson Med. John Wiley & Sons, Inc; 2001 Aug 1;46(2):412–6. doi: 10.1002/mrm.1206 11477648
7. Beenakker JWM, van Rijn GA, Luyten GPM, Webb AG. High-resolution MRI of uveal melanoma using a microcoil phased array at 7 T. NMR Biomed [Internet]. 2013 Dec;26(12):1864–9. Available from: doi: 10.1002/nbm.3041 24123279
8. Hafner S. Fast imaging in liquids and solids with the Back-projection Low Angle ShoT (BLAST) technique. Magn Reson Imaging. 1994;12(7):1047–51. doi: 10.1016/0730-725x(94)91236-p 7997092
9. Weiger M, Brunner DO, Dietrich BE, Müller CF, Pruessmann KP. ZTE imaging in humans. Magn Reson Med. 2013 Aug;70(2):328–32. doi: 10.1002/mrm.24816 23776142
10. Schieban K, Weiger M, Hennel F, Boss A, Pruessmann KP. ZTE imaging with enhanced flip angle using modulated excitation. Magn Reson Med. 2015 Sep;74(3):684–93. doi: 10.1002/mrm.25464 25242318
11. Larson PEZ, Han M, Krug R, Jakary A, Nelson SJ, Vigneron DB, et al. Ultrashort echo time and zero echo time MRI at 7T. Magn Reson Mater Phy. Springer Berlin Heidelberg; 2016 Jun;29(3):359–70.
12. Börnert P, Stehning C, Nehrke K, Groen J, Webb AG. Using high permittivity materials to improve ZTE image quality at 7T. 2015. p. 55.
13. Wong ST, Roos MS. A strategy for sampling on a sphere applied to 3D selective RF pulse design. Magn Reson Med. Wiley Subscription Services, Inc., A Wiley Company; 1994 Dec;32(6):778–84. doi: 10.1002/mrm.1910320614 7869901
14. Wu Y, Ackerman JL, Chesler DA, Li J, Neer RM, Wang J, et al. Evaluation of Bone Mineral Density Using Three-Dimensional Solid State Phosphorus-31 NMR Projection Imaging. Calcif Tissue Int. Springer-Verlag; 1998;62(6):512–8. doi: 10.1007/s002239900471 9576979
15. Dannels WR. Magnetic resonance imaging with short echo times. US Patent Office; 2009 Nov 24.
16. Brittain JH, Hu BS, Wright GA, Meyer CH, Macovski A, Nishimura DG. Coronary Angiography with Magnetization‐Prepared T2 Contrast. Magn Reson Med. Wiley Subscription Services, Inc., A Wiley Company; 1995 May 1;33(5):689–96. doi: 10.1002/mrm.1910330515 7596274
17. Balaban R, Ceckler T. Magnetization transfer contrast in magnetic resonance imaging. Magn Reson Quart. 1992;8(2):116–37.
18. Richdale K, Sinnott LT, Bullimore MA, Wassenaar PA, Schmalbrock P, Kao C-Y, et al. Quantification of age-related and per diopter accommodative changes of the lens and ciliary muscle in the emmetropic human eye. Invest Ophthalmol Vis Sci. The Association for Research in Vision and Ophthalmology; 2013 Feb;54(2):1095–105. doi: 10.1167/iovs.12-10619 23287789
19. Richdale K, Wassenaar P, Teal Bluestein K, Abduljalil A, Christoforidis JA, Lanz T, et al. 7 Tesla MR imaging of the human eye in vivo. J Magn Reson Imaging. 2009 Nov;30(5):924–32. doi: 10.1002/jmri.21959 19856406
20. Jones CE, Pope JM. Measuring optical properties of an eye lens using magnetic resonance imaging. Magn Reson Imaging. 2004 Feb;22(2):211–20. doi: 10.1016/j.mri.2003.07.005 15010113
21. Robson MD, Bydder GM. Clinical ultrashort echo time imaging of bone and other connective tissues. NMR Biomed. John Wiley & Sons, Ltd; 2006 Nov 1;19(7):765–80. doi: 10.1002/nbm.1100 17075960
22. Horch RA, Wilkens K, Gochberg DF, Does MD. RF coil considerations for short-T2 MRI. Magn Reson Med. 2010 Jul 27;64(6):1652–7. doi: 10.1002/mrm.22558 20665825
23. Griswold MA, Jakob PM, Heidemann RM, Nittka M, Jellus V, Wang J, et al. Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn Reson Med. John Wiley & Sons, Ltd; 2002 Jun;47(6):1202–10. doi: 10.1002/mrm.10171 12111967
24. Pruessmann KP, Weiger M, Scheidegger MB, Boesiger P. SENSE: sensitivity encoding for fast MRI. Magn Reson Med. 1999 Nov;42(5):952–62. 10542355
25. Wezel J, Garpebring A, Webb AG, van Osch MJP, Beenakker J-WM. Automated eye blink detection and correction method for clinical MR eye imaging. Magn Reson Med. 2017 Jul;78(1):165–71. doi: 10.1002/mrm.26355 27476861
26. Ferreira TA, Grech Fonk L, Jaarsma-Coes MG, van Haren GGR, Marinkovic M, Beenakker J-WM. MRI of Uveal Melanoma. Cancers (Basel). Multidisciplinary Digital Publishing Institute; 2019 Mar 17;11(3):377.
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PLOS One
2019 Číslo 9
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