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Characteristics of sarcopenia after distal gastrectomy in elderly patients


Autoři: Sadamu Takahashi aff001;  Shota Shimizu aff001;  Satoshi Nagai aff001;  Hiroshi Watanabe aff001;  Yuuko Nishitani aff001;  Yasuro Kurisu aff001
Působiště autorů: Department of Surgery, National Hospital Organization Hamada Medical Center, Asai-tyou, Hamada, Japan aff001
Vyšlo v časopise: PLoS ONE 14(9)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0222412

Souhrn

Presence of preoperative sarcopenia is a risk factor for postoperative complications. However, there are few reports on the presence of sarcopenia and its characteristics following gastrectomy. Sarcopenia is closely related to quality of life in elderly people. To date, the main purpose of follow-up after gastrectomy is surveillance for early detection of recurrence and secondary cancer. However, henceforth, quality of life in elderly gastric cancer patients after gastrectomy must also be evaluated. The present study aimed to investigate sarcopenia during a 1-year postoperative course in elderly gastric cancer patients and examine their characteristics. The subjects were 50 patients aged ≥70 years who underwent laparoscopy-assisted distal gastrectomy for gastric cancer and who experienced no recurrence 1 year postoperatively. Height, weight, serum albumin levels, food intake amount, grip strength, gait speed, visceral fat area, and appendicular skeletal muscle mass index were measured preoperatively and 6 months and 1 year postoperatively. Sarcopenia, obesity, and visceral obesity were diagnosed. Compared with preoperatively, indicators other than height decreased 6 months postoperatively. Compared with 6 months postoperatively, body weight, amount of food intake, and visceral fat area increased by 1 year postoperatively, unlike appendicular skeletal muscle mass index. The frequency of sarcopenia increased 6 months postoperatively compared with preoperatively; this frequency remained almost unchanged 1 year postoperatively compared with 6 months postoperatively. Further, the frequency of visceral obesity increased 1 year postoperatively compared with 6 months postoperatively. Weight increased after > 6 months postoperatively; however, most of the weight increase was in terms of fat and not muscle. We emphasize the importance of considering postoperative sarcopenia and visceral obesity. In particular, sarcopenia and visceral obesity should be carefully monitored after increases in body mass index and food consumption.

Klíčová slova:

Medicine and health sciences – Diagnostic medicine – Signs and symptoms – Sarcopenia – Pathology and laboratory medicine – Surgical and invasive medical procedures – Digestive system procedures – Gastrectomy – Body weight – Muscles – Skeletal muscles – Oncology – Cancers and neoplasms – Gastrointestinal tumors – Gastric cancer – Geriatrics – Biology and life sciences – Physiology – Physiological parameters – Obesity – Biochemistry – Lipids – Fats – Anatomy – Musculoskeletal system – People and places – Population groupings – Age groups – Elderly


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