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Educational and health outcomes associated with bronchopulmonary dysplasia in 15-year-olds born preterm


Autoři: David Drummond aff001;  Alice Hadchouel aff001;  Heloise Torchin aff002;  Jean-Christophe Rozé aff004;  Catherine Arnaud aff006;  Adèle Bellino aff009;  Laure Couderc aff010;  Stéphane Marret aff011;  Marie Mittaine aff012;  Didier Pinquier aff011;  Marie Vestraete aff013;  Jessica Rousseau aff014;  Pierre-Yves Ancel aff002;  Christophe Delacourt aff001
Působiště autorů: Paediatric Pulmonology, University Hospital Necker-Enfants Malades, AP-HP, Paris, France aff001;  Paris Descartes University, Paris, France aff002;  Port Royal Hospital, AP-HP, Paris, France aff003;  Department of Neonatal Medicine, Nantes University Hospital, Nantes, France aff004;  CIC004, Nantes University Hospital, Nantes, France aff005;  UMR1027, INSERM, Toulouse, France aff006;  Paul Sabatier University, Toulouse, France aff007;  Clinical Epidemiology Unit, CHU Purpan, Toulouse, France aff008;  Clinical Research Unit Cochin-Necker, AP-HP, Paris, France aff009;  Rouen University Hospital, Pediatric Pulmonology and Allergology, Inserm CIC-CRB 1404 Rouen, France aff010;  INSERM U1245, Team 4, Perinatal Neurological Handicap and Brain Protection, IRIB, School of Medicine, Normandy University, Rouen, France and Department of Neonatal Medicine and Neuropediatrics, Rouen University Hospital, Rouen, France aff011;  Paediatric Pulmonology and Allergology Department, CHU Purpan, Toulouse, France aff012;  CRCM Enfants, University Hospital, Nantes, France aff013;  Obstetrical, Perinatal, and Paediatric Epidemiology Team, Epidemiology and Biostatistics Sorbonne Paris Cité Research Centre (U1153), INSERM, Paris, France aff014;  Clinical Research Unit, Centre for Clinical Investigation, P1419 Cochin Broca Hôtel-Dieu, APHP, Paris, France aff015
Vyšlo v časopise: PLoS ONE 14(9)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0222286

Souhrn

Introduction

To evaluate the consequences of bronchopulmonary dysplasia (BPD) on academic outcomes and healthcare use in adolescents born very preterm.

Methods

This cohort study included 15-year-old adolescents born very preterm (< 32 weeks) between 2011 and 2013, with and without BPD, and controls born full term. Data regarding academic performance, current medical follow-up, and family characteristics were collected. Multivariate logistic regression was used to quantify relationships between academic outcomes and BPD.

Results

From the 1341 children included in the initial cohort, 985 adolescents were eligible and 351 included (55 preterms with a history of BPD, 249 without, and 47 controls). Among adolescents born very preterm, a history of BPD was associated with a higher risk to attend a school for children with special needs (p < 0.05) and to have repeated a grade (p = 0.01). It was also associated with an increased number of medical and paramedical consultations. A history of BPD was not associated with the parents’ employment status, family structure, or the presence of younger siblings.

Conclusion

This study highlights that a history of BPD is associated with poorer academic outcomes and high healthcare use in adolescence.

Klíčová slova:

People and places – Population groupings – Age groups – Children – Adolescents – Families – Ethnicities – European people – French people – Social sciences – Sociology – Education – Schools – Medicine and health sciences – Diagnostic medicine – Signs and symptoms – Dysplasia – Pathology and laboratory medicine – Hemorrhage – Vascular medicine – Physical sciences – Chemistry – Chemical compounds – Organic compounds – Steroids – Organic chemistry – Biology and life sciences – Developmental biology – Neonates


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