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Does age influence the quality of life in children with atopic dermatitis?


Autoři: Milena Ražnatović Đurović aff001;  Janko Janković aff002;  Vesna Tomić Spirić aff003;  Milijana Relić aff005;  Zorica Sojević Timotijević aff005;  Anđa Ćirković aff006;  Slađana Đurić aff007;  Slavenka Janković aff008
Působiště autorů: Clinic of Dermatology and Venereology, Clinical Center of Montenegro, Faculty of Medicine University of Montenegro, Podgorica, Montenegro aff001;  Institute of Social Medicine, Faculty of Medicine, University of Belgrade, Belgrade, Serbia aff002;  Department of Internal Medicine, Faculty of Medicine, University of Belgrade, Belgrade, Serbia aff003;  Clinic for Allergology and Immunology, Clinical Center of Serbia, Belgrade, Serbia aff004;  Department of Dermatology, Faculty of Medicine, University of Priština, Kosovska Mitrovica, Serbia aff005;  Institute of Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, Belgrade, Serbia aff006;  Department for Preventive Medicine, Faculty of Medicine, University of Priština, Kosovska Mitrovica, Serbia aff007;  Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia aff008
Vyšlo v časopise: PLoS ONE 14(11)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0224618

Souhrn

Background

Atopic dermatitis (AD) is one of the most common childhood skin diseases that can affect the quality of life (QoL) of children. The QoL of Montenegrin children with AD has not been sufficiently explored. The aim of this study was to assess their QoL with special emphasize on age differences.

Methods

This cross-sectional study included children with AD seen at the Clinic of Dermatology and Venereology, Clinical Center of Montenegro (CCM) in Podgorica between August 2017 and July 2018. The QoL was assessed with the Infants’ Dermatitis Quality of Life Index (IDQOL) and the Children’s Dermatology Life Quality Index (CDLQI). Disease severity was measured by the Three Item Severity (TIS) score.

Results

A total of 386 children with AD aged from newborn to 16 years took part in this study. The mean total score of the QoL was 14.7 in infants (0–4 years old), 19.4 in younger children (5–9 years old), and 16.6 in older children (10–16 years old). Age was in negative correlation with the CDLQI score, leisure domain of the CDLQI and CDLQI sleep, and in positive correlation with the IDQOL child mood. TIS score was in positive correlation with both the IDQOL and CDLQI score.

Conclusions

The QoL measured by CDLQI was more impaired in younger children, whilst IDQOL child mood was more impaired in older infants. The most impaired QoL was seen in children in the age group 5–9 years. Regardless of disease severity, treatment and counseling of children suffering from AD should be tailored specifically to their age.

Klíčová slova:

Age groups – Children – Infants – Quality of life – Swimming – Dermatology – Atopic dermatitis – Pruritus


Zdroje

1. Deckers IA, McLean S, Linssen S, Mommers M, van Schayck CP, Sheikh A. Investigating international time trends in the incidence and prevalence of atopic eczema 1990–2010: a systematic review of epidemiological studies. PLoS One. 2012;7(7):e39803. doi: 10.1371/journal.pone.0039803 22808063

2. Jackson KD, Howie LD, Akinbami LJ. Trends in allergic conditions among children: United States, 1997–2011. NCHS Data Brief. 2013;121: 1–8.

3. Hansen TE, Evjenth B, Holt J. Increasing prevalence of asthma, allergic rhinoconjunctivitis and eczema among schoolchildren: Three surveys during the period 1985–2008. Acta Paediatr. 2013;102: 47–52. doi: 10.1111/apa.12030 22994385

4. Williams H, Stewart A, von Mutius E, Cookson W, Anderson HR, ISAAC Phase One and Three Study Groups. Is eczema really on the increase worldwide? J Allergy Clin Immunol. 2008;121: 947–954. doi: 10.1016/j.jaci.2007.11.004 18155278

5. Al-Afif KAM, Buraik MA, Buddenkotte J, Mounir M, Gerber R, Ahmed HM, et al. Understanding the Burden of Atopic Dermatitis in Africa and the Middle East. Dermatol Ther (Heidelb). 2019;9: 223–241.

6. Verboom P, Hakkaart-Van L, Sturkenboom M, De Zeeuw R, Menke H, Rutten F. The cost of atopic dermatitis in the Netherlands: an international comparison. Br J Dermatol. 2002;147: 716–724. doi: 10.1046/j.1365-2133.2002.04964.x 12366418

7. Mancini AJ, Kaulback K, Chamlin SL. The socioeconomic impact of atopic dermatitis in the United States: a systematic review. Pediatr Dermatol. 2008;25: 1–6.

8. Carroll CL, Balkrishnan R, Feldman SR, Fleischer AB Jr, Manuel JC. The burden of atopic dermatitis: impact on the patient, family, and society. Pediatr Dermatol. 2005;22: 192–199. doi: 10.1111/j.1525-1470.2005.22303.x 15916563

9. Chamlin SL, Frieden IJ, Williams ML, Chren MM. Effects of atopic dermatitis on young American children and their families. Pediatrics. 2004;114: 607–611. doi: 10.1542/peds.2004-0374 15342828

10. Monti F, Agostini F, Gobbi F, Neri E, Schianchi S, Arcangeli F. Quality of life measures in Italian children with atopic dermatitis and their families. Ital J Pediatr. 2011;37: 59. doi: 10.1186/1824-7288-37-59 22192570

11. Amaral CS, March Mde F, Sant’Anna CC. Quality of life in children and teenagers with atopic dermatitis. An Bras Dermatol. 2012;87: 717–723. doi: 10.1590/s0365-05962012000500008 23044564

12. Marciniak J, Reich A, Szepietowski JC. Quality of Life of Parents of Children with Atopic Dermatitis. Acta Derm Venereol. 2017;97: 711–714. doi: 10.2340/00015555-2633 28207075

13. Holm EA, Wulf HC, Stegmann H, Jemec GB. Life quality assessment among patients with atopic eczema. Br J Dermatol. 2006;154: 719–725. doi: 10.1111/j.1365-2133.2005.07050.x 16536816

14. Boccardi D, D’Auria E, Turati F, DI Vito M, Sortino S, Riva E, et al. Disease severity and quality of life in children with atopic dermatitis: PO-SCORAD in clinical practice. Minerva Pediatr. 2017;69: 373–380. doi: 10.23736/S0026-4946.16.04294-8 26200523

15. Ng MS, Tan S, Chan NH, Foong AY, Koh MJ. Effect of atopic dermatitis on quality of life and its psychosocial impact in Asian adolescents. Australas J Dermatol. 2018;59:e114–e117. doi: 10.1111/ajd.12632 28836265

16. Ganemo A, Svensson A, Lindberg M, Wahlgren CF. Quality of life in Swedish Children with Eczema. Acta Derm Veneorol. 2007;87: 345–349.

17. Hon KL, Leung TF, Wong KY, Chow CM, Chuh A, Ng PC. Does age or gender influence quality of life in children with atopic dermatitis? Clin Exp Dermatol. 2008;33: 705–709. doi: 10.1111/j.1365-2230.2008.02853.x 18681872

18. Chernyshov PV, Ho RC, Monti F, Jirakova A, Velitchko SS, Hercogova J, et al. Gender Differences in Self-assessed Health-related Quality of Life in Children with Atopic Dermatitis. J Clin Aesthet Dermatol. 2016;9: 19–24.

19. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol (Stockh). 1980;92: 44–47.

20. Lewis-Jones MS, Finlay AY, Dykes PJ. The Infants’ Dermatitis Quality of Life Index. Br J Dermatol. 2001;144: 104–110. doi: 10.1046/j.1365-2133.2001.03960.x 11167690

21. Lewis-Jones MS, Finlay AY. The Children’s Dermatology Life Quality Index (CDLQI): initial validation and practical use. Br J Dermatol. 1995;132: 942–949. doi: 10.1111/j.1365-2133.1995.tb16953.x 7662573

22. Cardiff University, School of Medicine. The Infant’s Dermatitis Quality of Life Index (IDQOL)—different language versions—Serbian version. https://www.cardiff.ac.uk/medicine/resources/quality-of-life-questionnaires/infants-dermatitis-quality-of-life-index [Accessed 10 September 2019].

23. Cardiff University, School of Medicine. The Children’s Dermatology Life Quality Index (CDLQI)—different language versions—Serbian version. https://www.cardiff.ac.uk/medicine/resources/quality-of-life-questionnaires/childrens-dermatology-life-quality-index [Accessed 10 September 2019].

24. Wolkerstorfer A, de Waard-van der Spek FB, Glazenburg EJ, Mulder PG, Oranje AP. Scoring the severity of atopic dermatitis: three item severity (TIS) score as a rough system for daily practice and as a prescreening tool for studies. Acta Derm Venereol. 1999;79: 356–359. doi: 10.1080/000155599750010256 10494710

25. Oranje AP, Glazenburg EJ, Wolkerstorfer A, de Waard-van der Spek FB. Practical issues on interpretation of scoring atopic dermatitis: the SCORAD index, objective SCORAD and the three-item severity score. Br J Dermatol. 2007;157: 645–648. doi: 10.1111/j.1365-2133.2007.08112.x 17714568

26. Chernyshov PV, Ho RC, Monti F, Jirakova A, Velitchko SS, Hercogova J, et al. An international multicenter study on self-assessed and family quality of life in children with atopic dermatitis. Acta Dermatovenerol Croat. 2015;23: 247–253. 26724875

27. Maksimović N, Janković S, Marinković J, Sekulović LK, Zivković Z, Spirić VT. Health-related quality of life in patients with atopic dermatitis. J Dermatol. 2012;39: 42–47. doi: 10.1111/j.1346-8138.2011.01295.x 22044078

28. Jiráková A, Vojáčková N, Göpfertová D, Hercogová J. A comparative study of the impairment of quality of life in Czech children with atopic dermatitis of different age groups and their families. Int J Dermatol. 2012;51: 688–692. doi: 10.1111/j.1365-4632.2011.05175.x 22607286

29. Ben Gashir MA, Seed PT, Hay RJ. Quality of life and disease severity are correlated in children with atopic dermatitis. Br J Dermatol. 2004;150: 284–290. doi: 10.1111/j.1365-2133.2004.05776.x 14996099

30. Beattie PE, Lewis-Jones MS. A comparative study of impairment of quality of life in children with skin disease and children with other chronic childhood diseases. Br J Dermatol. 2006;155: 145–151. doi: 10.1111/j.1365-2133.2006.07185.x 16792766

31. Lewis-Jones S. Quality of life and childhood atopic dermatitis: the misery of living with childhood eczema. Int J Clin Pract. 2006;60: 984–992. doi: 10.1111/j.1742-1241.2006.01047.x 16893440

32. Buddenkotte J, Steinhoff M. Pathophysiology and therapy of pruritus in allergic and atopic diseases. Allergy. 2010;65: 805–821. doi: 10.1111/j.1398-9995.2010.01995.x 20384615

33. Darsow U, Pfab F, Valet M, Huss-Marp J, Behrendt H, Ring J, et al. Pruritus and atopic dermatitis. Clin Rev Allergy Immunol. 2011;41: 237–244. doi: 10.1007/s12016-010-8230-2 21207193

34. Arndt J, Smith N, Tausk F. Stress and atopic dermatitis. Curr Allergy Asthma Rep. 2008;8: 312–317. 18606083

35. Camfferman D, Kennedy JD, Gold M, Martin AJ, Lushington K. Eczema and sleep and its relationship to daytime functioning in children. Sleep medicine reviews. 2010;14: 359–369. doi: 10.1016/j.smrv.2010.01.004 20392655

36. Yosipovitch G, Goon AT, Wee J, Chan YH, Zucker I, Goh CL. Itch characteristics in Chinese patients with atopic dermatitis using a new questionnaire for the assessment of pruritus. Int J Dermatol. 2002;41: 212–216. doi: 10.1046/j.1365-4362.2002.01460.x 12031029

37. Reid P, Lewis-Jones MS. Sleep difficulties and their management in preschoolers with atopic eczema. Clin Exp Dermatol. 1995;20: 38–41. doi: 10.1111/j.1365-2230.1995.tb01280.x 7671394

38. Misery L, Finlay AY, Martin N, Boussetta S, Nguyen C, Myon E, et al. Atopic dermatitis: impact on the quality of life of patients and their partners. Dermatology. 2007;215: 123–129. doi: 10.1159/000104263 17684374

39. Kiebert G, Sorensen SV, Revicki D, Fagan SC, Doyle JJ, Cohen J, et al. Atopic dermatitis is associated with a decrement in health-related quality of life. Int J Dermatol. 2002;41: 151–158. doi: 10.1046/j.1365-4362.2002.01436.x 12010340

40. Kim DH, Li K, Seo SJ, Jo SJ, Yim HW, Kim CM, et al. Quality of life and disease severity are correlated in patients with atopic dermatitis. J Korean Med Sci. 2012;27: 1327–1332. doi: 10.3346/jkms.2012.27.11.1327 23166413

41. Alzolibani AA. Impact of atopic dermatitis on the quality of life of Saudi children. Saudi Med J. 2014;35: 391–396. 24749137

42. Ražnatović Djurović M, Janković J, Tomić Spirić V, Janković S. Health-related Quality of Life in Children with Moderate to Severe Atopic Dermatitis. Acta Dermatovenerol Croat. 2015;23: 178–184. 26476901

43. Chernyshov PV, Jirakova A, Ho RC, Moed H, Caldeira AP, Alvarenga TM, et al. An international multicenter study on quality of life and family quality of life in children with atopic dermatitis. Indian J Dermatol Venereol Leprol. 2013;79: 52–58. doi: 10.4103/0378-6323.104669 23254729


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