Integrated value-chain and risk assessment of Pig-Related Zoonoses in Ghana
Autoři:
Ayodele O. Majekodunmi aff001; Henry Ofosu Addo aff002; Husein Bagulo aff001; Langbong Bimi aff002
Působiště autorů:
Livestock and Poultry Research Centre, College of Basic and Applied Sciences, University of Ghana, Legon, Accra, Ghana
aff001; Department of Animal Biology & Conservation Science, College of Basic and Applied Sciences, University of Ghana, Legon, Accra, Ghana
aff002
Vyšlo v časopise:
PLoS ONE 14(11)
Kategorie:
Research Article
doi:
https://doi.org/10.1371/journal.pone.0224918
Souhrn
The marked increase in the pig-trade in Ghana has raised concerns about increased transmission of related zoonotic diseases. A study on pig-related zoonoses along the pork value-chain was conducted in Greater Accra and Upper East Regions of Ghana. Results showed significant taenia (60%) and trichinella (8%) seroprevalence in pigs in Upper East with little evidence of transmission to humans. Sero-prevalence of HEV was high in both pigs (85%) and humans (37%). Sero-prevalence rates were significantly higher in Upper East than Greater Accra. Pig handlers in Accra had significantly higher sero-prevalence rates (58%) than other community members (18%) but there was no such association in the Upper East. Given the high rates of mortality, miscarriage and stillbirth associated with HEV in pregnancy, it is a cause for concern that 31% women of child-bearing age tested sero-positive for HEV.
Klíčová slova:
Agricultural workers – Ghana – Hepatitis E virus – Sanitation – Swine – Zoonoses – Pork – Trichinella
Zdroje
1. Klous G, Huss A, Heederik DJJ, Coutinho RA. Human–livestock contacts and their relationship to transmission of zoonotic pathogens, a systematic review of literature. One Health. 2016;2:65–76. doi: 10.1016/j.onehlt.2016.03.001 28616478
2. Jones BA, Grace D, Kock R, Alonso S, Rushton J, Said MY, et al. Zoonosis emergence linked to agricultural intensification and environmental change. Proceedings of the National Academy of Sciences of the United States of America. 2013;110(21):8399–404. Epub 2013/05/13. doi: 10.1073/pnas.1208059110 23671097.
3. Sutton J, Kpentey B. An enterprise map of Ghana: International Growth Centre in association with the London Publishing Partnership; 2012.
4. Banson KE, Nketsia-Tabiri J, Anno K, Dagbui EK. Economic and market analysis of swine rearing and pork production in Ghana. Journal of Life Sciences, 2014; 8(8):699–708. 2014;8(8):669–708.
5. Knopp S, Steinmann P, Keiser J, Utzinger J. Nematode Infections: Soil-Transmitted Helminths and Trichinella. Infectious Disease Clinics of North America. 2012;26(2):341–58. doi: 10.1016/j.idc.2012.02.006 22632643
6. Van der Poel W, Rzezutka A. Hepatitis E. In: Rose B, Jiménez-Cisneros B, Meschke JS, Girones R, editors. Global Water Pathogen Project Part 3—Viruses. E. Lansing, MI: Michigan State University UNESCO.; 2017.
7. UNICEF, WHO. Progress on Sanitation and Drinking Water: 2015 Update and MDG Assessment. 2015.
8. Adjei AA, Aviyase JT, Tettey Y, Adu-Gyamfi C, Mingle JA, Ayeh-Kumi PF, et al. Hepatitis E virus infection among pig handlers in Accra, Ghana. East African Medical Journal. 2009;86(8):359–63. doi: 10.4314/eamj.v86i8.54155 20575309
9. Akuffo R, Brandful JAM, Zayed A, Adjei A, Watany N, Fahmy NT, et al. Crimean-Congo hemorrhagic fever virus in livestock ticks and animal handler seroprevalence at an abattoir in Ghana. BMC Infectious Diseases. 2016;16:324–9. doi: 10.1186/s12879-016-1660-6 27392037
10. Amegashie EA, Owusu-Dabo E, Salifu SP, Awuah AA-A, affour-Awuah SB, Addofoh N, et al. Seroprevalence and occupational risk factors for Brucella infection among slaughterhouse workers and butchers in Kumasi, Ghana. Journal of Epidemiological Research. 2017;3(1).
11. Amemor EA, Sackey SO, Yebuah N, Folitse RD, Emikpe BO, Afari E, et al. The prevalence of tuberculosis in cattle and their handlers in north Tongu, Volta region, Ghana. African Journal of Infectious Diseases. 2017;11(1).
12. Amfo-Otu R, Agyenim JB, Adzraku S. Meat Contamination Through Singeing With Scrap Tyres In Akropong-Akuapem Abattoir, Ghana. Applied Research Journal. 2014;1(1).
13. Asenso NT, Emikpe BO, Folitse RD, Opoku-Agyemang T, Burimuah V. The incidence and pattern of pneumonia in pigs slaughtered at the Kumasi abattoir, Ghana. Bulletin of Animal Health and Production in Africa. 2015;63(1).
14. Atawalna J, Ewura S, Mensah M. Prevalence and Financial Losses Associated with Porcine Cysticercosis in the Kumasi Metropolis of Ghana. International Journal of Livestock Research. 2015;5(9).
15. Permin A, Yelifari L, Bloch P, Steenhard N, Hansen NP, Nansen P. Parasites in cross-bred pigs in the Upper East Region of Ghana. Veterinary parasitology. 1999;87(1):63–71. doi: 10.1016/s0304-4017(99)00159-4 10628701
16. Bonney JH, Kwame-Aryee RA, Obed S, Tamatey AA, Barnor JS, Armah NB, et al. Fatal hepatitis E viral infection in pregnant women in Ghana: a case series. BMC Res Notes. 2012;5:478. Epub 2012/09/04. doi: 10.1186/1756-0500-5-478 22937872; PubMed Central PMCID: PMC3504539.
17. Bonney JH, Osei-Kwasi M, Adiku TK, Barnor JS, Amesiya R, Kubio C, et al. Hospital-based surveillance for viral hemorrhagic fevers and hepatitides in Ghana. PLoS Negl Trop Dis. 2013;7(9):e2435. Epub 2013/09/27. doi: 10.1371/journal.pntd.0002435 24069490; PubMed Central PMCID: PMC3777898.
18. Feldt T, Sarfo FS, Zoufaly A, Phillips RO, Burchard G, van Lunzen J, et al. Hepatitis E virus infections in HIV-infected patients in Ghana and Cameroon. Journal of clinical virology: the official publication of the Pan American Society for Clinical Virology. 2013;58(1):18–23. Epub 2013/06/08. doi: 10.1016/j.jcv.2013.05.004 23743346.
19. Meldal BH, Sarkodie F, Owusu-Ofori S, Allain JP. Hepatitis E virus infection in Ghanaian blood donors—the importance of immunoassay selection and confirmation. Vox sanguinis. 2013;104(1):30–6. Epub 2012/08/01. doi: 10.1111/j.1423-0410.2012.01637.x 22845878.
20. Tettey Y, Adjei A, Ayivase J, Adu-Gyamfi C, Mingle J, Nartey E, et al. Serological evidence of hepatitis E virus infection among volunteer blood donors at the Accra area blood transfusion center, Accra, Ghana. Journal of the Ghana Science Association. 2011;13(2):64–73.
21. Kim JH, Nelson KE, Panzner U, Kasture Y, Labrique AB, Wierzba TF. A systematic review of the epidemiology of hepatitis E virus in Africa. BMC Infect Dis. 2014;14:308. Epub 2014/06/07. doi: 10.1186/1471-2334-14-308 24902967; PubMed Central PMCID: PMC4055251.
22. Martinson FE, Marfo VY, Degraaf J. Hepatitis E virus seroprevalence in children living in rural Ghana. West African journal of medicine. 1999;18(2):76–9. Epub 1999/10/03. 10504860.
23. Patra S, Kumar A, Trivedi SS, Puri M, Sarin SK. Maternal and fetal outcomes in pregnant women with acute hepatitis E virus infection. Annals of internal medicine. 2007;147(1):28–33. doi: 10.7326/0003-4819-147-1-200707030-00005 17606958
24. Krain LJ, Atwell JE, Nelson KE, Labrique AB. Fetal and neonatal health consequences of vertically transmitted hepatitis E virus infection. The American journal of tropical medicine and hygiene. 2014;90(2):365–70. doi: 10.4269/ajtmh.13-0265 24420778
25. Navaneethan U, Mohajer MA, Shata MT. Hepatitis E and Pregnancy- Understanding the pathogenesis. Liver international: official journal of the International Association for the Study of the Liver. 2008;28(9):1190–9. doi: 10.1111/j.1478-3231.2008.01840.x PMC2575020. 18662274
26. Traore KA, Ouoba JB, Huot N, Rogee S, Dumarest M, Traore AS, et al. Hepatitis E Virus Exposure is Increased in Pork Butchers from Burkina Faso. Am J Trop Med Hyg. 2015;93(6):1356–9. Epub 2015/10/07. doi: 10.4269/ajtmh.15-0321 26438027; PubMed Central PMCID: PMC4674258.
27. Owolodun OA, Gerber PF, Gimenez-Lirola LG, Kwaga JK, Opriessnig T. First report of hepatitis E virus circulation in domestic pigs in Nigeria. Am J Trop Med Hyg. 2014;91(4):699–704. Epub 2014/07/09. doi: 10.4269/ajtmh.14-0144 25002299; PubMed Central PMCID: PMC4183390.
28. Antia RE, Adekola AA, Jubril AJ, Ohore OG, Emikpe BO. Hepatitis E Virus infection seroprevalence and the associated risk factors in animals raised in Ibadan, Nigeria. Journal of immunoassay & immunochemistry. 2018;39(5):509–20. Epub 2018/09/14. doi: 10.1080/15321819.2018.1514507 30212262.
29. Temmam S, Besnard L, Andriamandimby SF, Foray C, Rasamoelina-Andriamanivo H, Heraud JM, et al. High prevalence of hepatitis E in humans and pigs and evidence of genotype-3 virus in swine, Madagascar. Am J Trop Med Hyg. 2013;88(2):329–38. Epub 2012/12/05. doi: 10.4269/ajtmh.2012.12-0615 23208879; PubMed Central PMCID: PMC3583326.
30. Adjei AA, Aviyase JT, Tettey Y, Adu-Gyamfi C, Mingle JA, Ayeh-Kumi PF, et al. Hepatitis E virus infection among pig handlers in Accra, Ghana. East African medical journal. 2009;86(8):359–63. Epub 2010/06/26. doi: 10.4314/eamj.v86i8.54155 20575309.
31. Adjei AA, Tettey Y, Aviyase JT, Adu-Gyamfi C, Mingle JA, Nartey ET. Unexpected elevated alanine aminotransferase, aspartate aminotransferase levels and hepatitis E virus infection among persons who work with pigs in accra, Ghana. Virology journal. 2010;7:336. Epub 2010/11/26. doi: 10.1186/1743-422X-7-336 21092196; PubMed Central PMCID: PMC2995795.
32. Ukuli AQ, Mugimba KK. Seroprevalence of hepatitis E in swine abattoir workers. African health sciences. 2017;17(4):1022–8. Epub 2018/06/26. doi: 10.4314/ahs.v17i4.9 29937872; PubMed Central PMCID: PMC5870292.
33. Madden RG, Wallace S, Sonderup M, Korsman S, Chivese T, Gavine B, et al. Hepatitis E virus: Western Cape, South Africa. World J Gastroenterol. 2016;22(44):9853–9. doi: 10.3748/wjg.v22.i44.9853 27956810.
34. Robb K, Null C, Teunis P, Yakubu H, Armah G, Moe CL. Assessment of Fecal Exposure Pathways in Low-Income Urban Neighborhoods in Accra, Ghana: Rationale, Design, Methods, and Key Findings of the SaniPath Study. The American journal of tropical medicine and hygiene. 2017;97(4):1020–32. Epub 2017/07/17. doi: 10.4269/ajtmh.16-0508 28722599.
35. Ninkuu MV, Adetunde LA, Nsoh AC, Guri M, Asare AB. Assessment of bacteriological quality of Tono and Vea dams water in the Upper East Region, Ghana. British Microbiology Research Journal. 2015;7(1):10–7.
36. Otupiri E, Adam M, Laing E, Akanmori BD. Detection and management of zoonotic diseases at the Kumasi slaughterhouse in Ghana. Acta Trop. 2000;76(1):15–9. Epub 2000/07/29. doi: 10.1016/s0001-706x(00)00083-8 10913760.
Článek vyšel v časopise
PLOS One
2019 Číslo 11
- Jak a kdy u celiakie začíná reakce na lepek? Možnou odpověď poodkryla čerstvá kanadská studie
- Pomůže v budoucnu s triáží na pohotovostech umělá inteligence?
- Spermie, vajíčka a mozky – „jednohubky“ z výzkumu 2024/38
- Metamizol jako analgetikum první volby: kdy, pro koho, jak a proč?
- Infekce se v Americe po příjezdu Kolumba šířily nesrovnatelně déle, než se traduje
Nejčtenější v tomto čísle
- A daily diary study on maladaptive daydreaming, mind wandering, and sleep disturbances: Examining within-person and between-persons relations
- A 3’ UTR SNP rs885863, a cis-eQTL for the circadian gene VIPR2 and lincRNA 689, is associated with opioid addiction
- A substitution mutation in a conserved domain of mammalian acetate-dependent acetyl CoA synthetase 2 results in destabilized protein and impaired HIF-2 signaling
- Molecular validation of clinical Pantoea isolates identified by MALDI-TOF
Zvyšte si kvalifikaci online z pohodlí domova
Všechny kurzy