Cost-consequence analysis of influenza vaccination among the staff of a large teaching hospital in Rome, Italy: A pilot study
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Vittoria Colamesta aff001; Andrea Tamburrano aff001; Andrea Barbara aff001; Andrea Gentili aff001; Daniele Ignazio La Milia aff003; Filippo Berloco aff003; Americo Cicchetti aff004; Daniele Piacentini aff005; Roberta Galluzzi aff005; Sergio Riccardo Mastrodonato aff005; Andrea Cambieri aff003; Walter Ricciardi aff001; Patrizia Laurenti aff001
Působiště autorů:
Università Cattolica del Sacro Cuore, Section of Hygiene - Institute of Public Health, Roma, Italia
aff001; Local Health Unit ASL RM1, UOC Direzione Sanitaria S. Spirito e Nuovo Regina Margherita, Roma, Italia
aff002; Fondazione Policlinico Universitario A. Gemelli IRCCS, Hospital Health Management, Roma, Italia
aff003; Università Cattolica del Sacro Cuore, Postgraduate School of Health Economics and Management (ALTEMS), Roma, Italia
aff004; Fondazione Policlinico Universitario A. Gemelli IRCCS, Human Resources Management, Roma, Italia
aff005; Fondazione Policlinico Universitario A. Gemelli IRCCS, Department of Woman and Child Health and Public Health, Roma, Italia
aff006
Vyšlo v časopise:
PLoS ONE 14(11)
Kategorie:
Research Article
doi:
https://doi.org/10.1371/journal.pone.0225326
Souhrn
Flu vaccination, as well as being effective to prevent seasonal influenza, decreases staff illness and absenteeism and reduces costs resulting from loss of productivity. Despite the effectiveness of flu vaccination, the seasonal coverage among healthcare workers is usually low. The aim of this retrospective observational study was to analyze the vaccination coverage rate among all employees (healthcare workers and administrative staff) of a large teaching hospital in Rome during the 2017–2018 influenza season, to perform a cost-consequence analysis of influenza vaccination (by evaluating the absenteeism due to illness in the epidemic period), and to assess the impact of vaccination in terms of both costs and sick days. The flu vaccination coverage rate was 9.8% among 4631 healthcare workers and 852 administrative employees. The human capital approach estimated a loss of productivity equal to 297.06 € for each vaccinated worker and 517.22 € for each unvaccinated worker (cost-outcome ratio: 120.07 €/sick day). Applying the friction cost method, a loss of productivity equal to 237.65 € for each vaccinated worker and 413.78 € for each unvaccinated worker (cost-outcome ratio: 104.19 €/sick day) was found. These results confirm the benefits of the flu vaccination for the society and the company. This allowed the management to grant one hour of permission to the flu-vaccinated workers in the following annual vaccination campaign (2018–2019).
Klíčová slova:
Employment – Influenza – Italian people – Italy – Nurses – Social systems – Vaccination and immunization – Vaccines
Zdroje
1. World Health Organization. Influenza vaccines. WHO position paper. Weekly epidemiological record 2005; 33 (80): 277–88 [Internet]. [cited 2018 Dec 21].
2. Who.int. (2018). Influenza (Seasonal). [online] https://www.who.int/news-room/fact-sheets/detail/influenza-(seasonal) [Accessed 15 Feb. 2019].
3. ECDC. (2018). Seasonal influenza vaccines. [online] https://ecdc.europa.eu/en/seasonal-influenza/prevention-and-control/seasonal-influenza-vaccines [Accessed 15 Feb. 2019].
4. WHO. (2019). Vaccines. [online] https://www.who.int/topics/vaccines/en/ [Accessed 15 Feb. 2019].
5. Karafillakis E., Dinca I., Apfel F., Cecconi S., Wűrz A., Takacs J., et al. (2016). Vaccine hesitancy among healthcare workers in Europe: A qualitative study. Vaccine. https://doi.org/10.1016/j.vaccine.2016.08.029.
6. WHO. Weekly epidemiological record. Vaccines against influenza WHO position paper—November 2012. 2012;87:461–76.
7. Ministero della Salute. Piano Nazionale Prevenzione Vaccinale 2017–19 [Internet]. 2017 [cited 2018 Oct 22].
8. Mereckiene, J. (2018). Seasonal influenza vaccination and antiviral use in EU/EEA Member States. [ebook] Stockholm: European Centre for Disease Prevention and Control. https://ecdc.europa.eu/sites/portal/files/documents/Seasonal-influenza-antiviral-use-EU-EEA-Member-States-December-2018_0.pdf [Accessed 15 Feb. 2019].
9. La Torre G., Mannocci A., Ursillo P., Bontempi C., Firenze A., Panico M. G., et al. (2011). Prevalence of influenza vaccination among nurses and ancillary workers in Italy: Systematic review and meta analysis. Human Vaccines. https://doi.org/10.4161/hv.7.7.15413.
10. Mannocci A., Ursillo P., Bontempi C., Sferrazza A., La Torre G. (2010). Prevalence of influenza vaccination among physicians and related enhancing and preventing factors in Italy. Reviews in Health Care. https://doi.org/10.7175/rhc.v1i1.15.
11. Amodio E., Restivo V., Firenze A., Mammina C., Tramuto F., Vitale F. (2014). Can influenza vaccination coverage among healthcare workers influence the risk of nosocomial influenza-like illness in hospitalized patients? Journal of Hospital Infection. https://doi.org/10.1016/j.jhin.2014.01.005;
12. Esposito S., Bosis S., Pelucchi C., Tremolati E., Sabatini C., Semino M., et al. (2008). Influenza vaccination among healthcare workers in a multidisciplinary University hospital in Italy. BMC Public Health. https://doi.org/10.1186/1471-2458-8-422.
13. Alicino C., Iudici R., Barberis I., Paganino C., Cacciani R., Zacconi M., et al. (2015). Influenza vaccination among healthcare workers in Italy. Human Vaccines & Immunotherapeutics. https://doi.org/10.4161/hv.34362.
14. Corsaro A., Poscia A., De Waure C., De Meo C., Berloco F., Ricciardi W., et al. (2017). Fostering flu vaccination in healthcare workers: Forum theatre in a university hospital. Medical Science Monitor. https://doi.org/10.12659/MSM.903009.
15. Barbara A., Giubbini G., De Waure C., Poscia A., De Meo C., Berloco F., et al. (2017). Is the on site flu vaccination among health care workers effective? A Italian teaching hospital case. European Journal of Public Health. https://doi.org/10.1093/eurpub/ckx187.380.
16. Barbara A., Mariani M., De Waure C., Anzelmo V., Piccoli B., Cambieri A., et al. (2019). A campaign aimed at increasing seasonal influenza vaccination coverage among post graduate medical residents in an Italian teaching hospital. Human Vaccines and Immunotherapeutics. https://doi.org/10.1080/21645515.2018.1556076.
17. ALTEMS (Alta Scuola di Economia e Management dei Sistemi Sanitari). L’impatto economico e fiscale della vaccinazione degli adulti in Italia. (Executive summary) [Internet]. 2017 [cited 2018 Nov 30].
18. Gianino M. M., Politano G., Scarmozzino A., Charrier L., Testa M., Giacomelli S., et al. (2017). Estimation of sickness absenteeism among Italian healthcare workers during seasonal influenza epidemics. PloS One. https://doi.org/10.1371/journal.pone.0182510.
19. Amodio E., Anastasi G., di Pasquale M., Gelsomino V., Morici M., Romano N., et al. (2010). Influenza vaccination among healthcare workers and absenteeism from work due to influenza-like illness in a teaching hospital in Palermo. Italian Journal of Public Health. https://doi.org/10.2427/5715.
20. Cella, M. T., Corona, G., Tuccillo, E., Franco, G. (2005). Valutazione di efficacia e impatto economico di una campagna di vaccinazione antinfluenzale in personale di una struttura sanitaria. Medicina Del Lavoro.
21. CDC. Academic Detailing: Frequently Asked Questions [Internet]. [cited 2018 Dec 11].
22. Istituto Superiore di Sanità. Influnet. [Internet]. [cited 2018 Dec 11].
23. Mauskopf J. A., Paul J. E., Grant D. M., Stergachis A. (1998). The role of cost-consequence analysis in healthcare decision-making. PharmacoEconomics. https://doi.org/10.2165/00019053-199813030-00002.
24. Capri S., Barbieri M., de Waure C., Boccalini S., Panatto D. (2018). Cost-effectiveness analysis of different seasonal influenza vaccines in the elderly Italian population. Human Vaccines and Immunotherapeutics. https://doi.org/10.1080/21645515.2018.1438792
25. Kheiraoui F, Cadeddu C, Quaranta G, Poscia A, Raponi M, de Waure C, et al. [Health technology assessment of the quadrivalent influenza vaccine Flu-QIV (Fluarix Tetra)]. QIJPH. 2015;4.
26. Gazzetta Ufficiale della Repubblica Italiana. Remunerazione delle prestazioni di assistenza ospedaliera per acuti, assistenza ospedaliera di riabilitazione e di lungodegenza post acuzie e di assistenza specialistica ambulatoriale. 28 Gennaio. 2013.
27. Nomenclatore tariffario delle prestazioni aggiuntive, Accordo Collettivo Nazionale medici generici, 23 marzo. 2005.
28. Contratti Collettivi Nazionali della Sanità [Internet]. Aranagenzia.it. 2019 [cited 30 August 2019]. https://www.aranagenzia.it/contrattazione/comparti/comparto-della-sanita/contratti.html.
29. Gianino M. M., Petrinco M., Galzerano M., Gregori D., Ferrando A., Pagano E. (2009). Methodological aspects in valuing loss of production and informal care in cost-of-illness studies. Epidemiologia e Prevenzione.
30. Koopmanschap M. A., Rutten F. F. H., van Ineveld B. M., van Roijen L. (1995). The friction cost method for measuring indirect costs of disease. Journal of Health Economics. https://doi.org/10.1016/0167-6296(94)00044-5.
31. Hammond G. W., Cheang M. (1984). Absenteeism among hospital staff during an influenza epidemic: Implications for immunoprophylaxis. Canadian Medical Association Journal.
32. Yassi A., Kettner J., Hammond G., Cheang M., McGill M. (1991). Effectiveness and Cost-Benefit of an Influenza Vaccination Program for Health Care Workers. Canadian Journal of Infectious Diseases. https://doi.org/10.1155/1991/376502.
33. Nguyen-Van-Tam J., Granfield R., Pearson J., Fleming D., Keating N. (1999). Do Influenza Epidemics Affect Patterns of Sickness Absence Among British Hospital Staff? Infection Control & Hospital Epidemiology. https://doi.org/10.1086/501568.
34. Pradas-Velasco R., Antoñanzas-Villar F., Martínez-Zárate M. P. (2008). Dynamic modelling of infectious diseases: An application to the economic evaluation of influenza vaccination. PharmacoEconomics. https://doi.org/10.2165/00019053-200826010-00005
35. Gjini E., Gomes M. G. M. (2016). Expanding vaccine efficacy estimation with dynamic models fitted to cross-sectional prevalence data post-licensure. Epidemics. https://doi.org/10.1016/j.epidem.2015.11.001.
36. Eichner M., Schwehm M., Eichner L., Gerlier L. (2017). Direct and indirect effects of influenza vaccination. BMC Infectious Diseases. https://doi.org/10.1186/s12879-017-2399-4.
37. The Global Action Plan for Influenza Vaccines. Geneva, Switzerland: World Health Organization; 2012.
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PLOS One
2019 Číslo 11
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