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Using electronic health record system triggers to target delivery of a patient-centered intervention to improve venous thromboembolism prevention for hospitalized patients: Is there a differential effect by race?


Autoři: Oluwafemi P. Owodunni aff001;  Elliott R. Haut aff001;  Dauryne L. Shaffer aff001;  Deborah B. Hobson aff001;  Jiangxia Wang aff007;  Gayane Yenokyan aff007;  Peggy S. Kraus aff008;  Jonathan K. Aboagye aff001;  Katherine L. Florecki aff001;  Kristen L. W. Webster aff001;  Christine G. Holzmueller aff001;  Michael B. Streiff aff004;  Brandyn D. Lau aff004
Působiště autorů: Division of Acute Care Surgery, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America aff001;  Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America aff002;  Department of Emergency Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America aff003;  Armstrong Institute for Patient Safety and Quality, Johns Hopkins Medicine, Baltimore, Maryland, United States of America aff004;  Department of Health Policy and Management, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America aff005;  Department of Nursing, The Johns Hopkins Hospital, Baltimore, Maryland, United States of America aff006;  Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America aff007;  Department of Pharmacy, The Johns Hopkins Hospital, Baltimore, Maryland, United States of America aff008;  Division of Hematology, Department of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland, United States of America aff009;  Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Hospital, Baltimore, Maryland, United States of America aff010;  Division of Health Sciences Informatics, The Johns Hopkins Hospital, Baltimore, Maryland, United States of America aff011
Vyšlo v časopise: PLoS ONE 15(1)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0227339

Souhrn

Background

Racial disparities are common in healthcare. Venous thromboembolism (VTE) is a leading cause of preventable harm, and disparities observed in prevention practices. We examined the impact of a patient-centered VTE education bundle on the non-administration of preventive prophylaxis by race.

Methods

A post-hoc, subset analysis (stratified by race) of a larger nonrandomized trial. Pre-post comparisons analysis were conducted on 16 inpatient units; study periods were October 2014 through March 2015 (baseline) and April through December 2015 (post-intervention). Patients on 4 intervention units received the patient-centered, nurse educator-led intervention if the electronic health record alerted a non-administered dose of VTE prophylaxis. Patients on 12 control units received no intervention. We compared the conditional odds of non-administered doses of VTE prophylaxis when patient refusal was a reason for non-administration, stratified by race.

Results

Of 272 patient interventions, 123 (45.2%) were white, 126 (46.3%) were black, and 23 (8.5%) were other races. A significant reduction was observed in the odds of non-administration of prophylaxis on intervention units compared to control units among patients who were black (OR 0.61; 95% CI, 0.46–0.81, p<0.001), white (OR 0.57; 95% CI, 0.44–0.75, p<0.001), and other races (OR 0.50; 95% CI, 0.29–0.88, p = 0.015).

Conclusion

Our finding suggests that the patient education materials, developed collaboratively with a diverse group of patients, improved patient’s understanding and the importance of VTE prevention through prophylaxis. Quality improvement interventions should examine any differential effects by patient characteristics to ensure disparities are addressed and all patients experience the same benefits.

Klíčová slova:

Health education and awareness – Nurses – Nursing education – Patients – Prophylaxis – Socioeconomic aspects of health – Surgical and invasive medical procedures – Venous thromboembolism


Zdroje

1. Singh GK, Daus GP, Allender M, Ramey CT, Martin EK, Perry C, et al. Social Determinants of Health in the United States: Addressing Major Health Inequality Trends for the Nation, 1935–2016. Int J MCH AIDS 2017;6(2):139–164. doi: 10.21106/ijma.236 29367890

2. Rodriguez-Lainz A, McDonald M, Fonseca-Ford M, Penman-Aguilar A, Waterman SH, Truman BI, et al. Collection of Data on Race, Ethnicity, Language, and Nativity by US Public Health Surveillance and Monitoring Systems: Gaps and Opportunities. Public Health Rep 2018 Jan/Feb;133(1):45–54. doi: 10.1177/0033354917745503 29262290

3. Filice CE, Joynt KE. Examining Race and Ethnicity Information in Medicare Administrative Data. Med Care 2017 Dec;55(12):e170–e176. doi: 10.1097/MLR.0000000000000608 29135782

4. Narayan MC, Scafide KN. Systematic Review of Racial/Ethnic Outcome Disparities in Home Health Care. J Transcult Nurs 2017 Mar 1:1043659617700710.

5. Kawachi I, Subramanian SV, Almeida-Filho N. A glossary for health inequalities. J Epidemiol Community Health 2002 Sep;56(9):647–652. doi: 10.1136/jech.56.9.647 12177079

6. Braveman P, Gruskin S. Defining equity in health. J Epidemiol Community Health 2003 Apr;57(4):254–258. doi: 10.1136/jech.57.4.254 12646539

7. Mackenbach JP. The persistence of health inequalities in modern welfare states: the explanation of a paradox. Soc Sci Med 2012 Aug;75(4):761–769. doi: 10.1016/j.socscimed.2012.02.031 22475407

8. Haider AH, Schneider EB, Sriram N, Dossick DS, Scott VK, Swoboda SM, et al. Unconscious race and class bias: Its association with decision making by trauma and acute care surgeons. J Trauma Acute Care Surg 2014 Sep;77(3):409–416. doi: 10.1097/TA.0000000000000392 25159243

9. Streiff MB, Lau BD. Thromboprophylaxis in nonsurgical patients. Hematology Am Soc Hematol Educ Program 2012;2012:631–637. 23233645

10. Haut ER, Aboagye JK, Shaffer DL, Wang J, Hobson DB, Yenokyan G, et al. Effect of Real-Time Patient-Centered Education Bundle on Venous Thromboembolism Prevention in Hospitalized Patients. JAMA Netw Open 2018;1(7):e184741. doi: 10.1001/jamanetworkopen.2018.4741 30646370

11. Lau BD, Streiff MB, Pronovost PJ, Haut ER. VTE quality measures fail to accurately measure quality. Circulation 2018;137(12):1278–1284. doi: 10.1161/CIRCULATIONAHA.116.026897 29555709

12. Lau BD, Arnaoutakis GJ, Streiff MB, Howley IW, Poruk KE, Beaulieu R, et al. Individualized Performance Feedback to Surgical Residents Improves Appropriate Venous Thromboembolism Prophylaxis Prescription and Reduces Potentially Preventable VTE: A Prospective Cohort Study. Ann Surg 2016 Dec;264(6):1181–1187. doi: 10.1097/SLA.0000000000001512 26649586

13. Lau BD, Haut ER. Practices to prevent venous thromboembolism: a brief review. BMJ Qual Saf 2014 Mar;23(3):187–195. doi: 10.1136/bmjqs-2012-001782 23708438

14. Muellner SK, Haut ER, Streiff MB, Holcomb JB, Cotton BA. ABO blood group as a potential risk factor for venous thromboembolism in acutely injured patients. Thromb Haemost 2011 Jan 3;105(1):5–13. doi: 10.1160/TH10-08-0504 21103665

15. Margaglione M, Grandone E. Population genetics of venous thromboembolism. A narrative review. Thromb Haemost 2011 Feb;105(2):221–231. doi: 10.1160/TH10-08-0510 20941456

16. Key NS, Reiner AP. Genetic basis of ethnic disparities in VTE risk. Blood 2016 Apr 14;127(15):1844–1845. doi: 10.1182/blood-2016-03-701698 27081095

17. Fiscella K, Franks P, Gold MR, Clancy CM. Inequality in quality: addressing socioeconomic, racial, and ethnic disparities in health care. JAMA 2000 May 17;283(19):2579–2584. doi: 10.1001/jama.283.19.2579 10815125

18. White RH, Keenan CR. Effects of race and ethnicity on the incidence of venous thromboembolism. Thromb Res 2009;123 Suppl 4:S11–7.

19. Owodunni OP, Weiss MJ, Haut ER. Is Venous Thromboembolism in Asian Patients Undergoing Gastrectomy Different From Venous Thromboembolism in Their Western Counterparts? JAMA Surg 2018 Jul 18.

20. Streiff MB, Lau BD, Hobson DB, Kraus PS, Shermock KM, Shaffer DL, et al. The Johns Hopkins Venous Thromboembolism Collaborative: Multidisciplinary team approach to achieve perfect prophylaxis. J Hosp Med 2016 Dec;11 Suppl 2:S8–S14.

21. Streiff MB, Carolan H, Hobson DB, Kraus PS, Holzmueller C, Demski R, et al. Lessons from the Johns Hopkins Multi-Disciplinary Venous Thromboembolism (VTE) Prevention Collaborative. BMJ 2012;344:e3935. doi: 10.1136/bmj.e3935 22718994

22. Lau BD, Haider AH, Streiff MB, Lehmann CU, Kraus PS, Hobson DB, et al. Eliminating Health Care Disparities With Mandatory Clinical Decision Support: The Venous Thromboembolism (VTE) Example. Med Care 2015 Jan;53(1):18–24. doi: 10.1097/MLR.0000000000000251 25373403

23. Lau BD, Streiff MB, Hobson DB, Kraus PS, Shaffer DL, Popoola VO, et al. Beneficial "halo effects" of surgical resident performance feedback. J Surg Res 2016 Sep;205(1):179–185. doi: 10.1016/j.jss.2016.06.024 27621016

24. Zeidan AM, Streiff MB, Lau BD, Ahmed SR, Kraus PS, Hobson DB, et al. Impact of a venous thromboembolism prophylaxis "smart order set": Improved compliance, fewer events. Am J Hematol 2013 Jul;88(7):545–549. doi: 10.1002/ajh.23450 23553743

25. Haut ER, Lau BD, Kraenzlin FS, Hobson DB, Kraus PS, Carolan HT, et al. Improved Prophylaxis and Decreased Preventable Harm with a Mandatory Computerized Clinical Decision Support Tool for Venous Thromboembolism (VTE) Prophylaxis in Trauma Patients. Arch Surg 2012;10(147):901–907.

26. Lau BD, Streiff MB, Kraus PS, Hobson DB, Shaffer DL, Aboagye JK, et al. Missed Doses of Venous Thromboembolism (VTE) Prophylaxis at Community Hospitals: Cause for Alarm. J Gen Intern Med 2018 Jan;33(1):19–20. doi: 10.1007/s11606-017-4203-y 29043537

27. Shermock KM, Lau BD, Haut ER, Hobson DB, Ganetsky VS, Kraus PS, et al. Patterns of Non-Administration of Ordered Doses of Venous Thromboembolism Prophylaxis: Implications for Novel Intervention Strategies. PLoS One 2013 Jun 14;8(6):e66311. doi: 10.1371/journal.pone.0066311 23799091

28. Farrow NE, Lau BD, JohnBull EA, Hobson DB, Kraus PS, Taffe ER, et al. Is the Meaningful Use Venous Thromboembolism VTE-6 Measure Meaningful? A retrospective analysis of one hospital’s VTE-6 cases. Jt Comm J Qual Patient Saf 2016;42(9):410–416. doi: 10.1016/s1553-7250(16)42082-9 27535458

29. Haut ER, Lau BD, Kraus PS, Hobson DB, Maheshwari B, Pronovost PJ, et al. Preventability of Hospital-Acquired Venous Thromboembolism. JAMA Surg 2015 Jul 29;150(9):912–925. doi: 10.1001/jamasurg.2015.1340 26222738

30. Popoola VO, Lau BD, Shihab HM, Farrow NE, Shaffer DL, Hobson DB, et al. Patient Preferences for Receiving Education on Venous Thromboembolism Prevention—A Survey of Stakeholder Organizations. PLoS One 2016 Mar 31;11(3):e0152084. doi: 10.1371/journal.pone.0152084 27031330

31. Weiss D, Rydland HT, Oversveen E, Jensen MR, Solhaug S, Krokstad S. Innovative technologies and social inequalities in health: A scoping review of the literature. PLoS One 2018 Apr 3;13(4):e0195447. doi: 10.1371/journal.pone.0195447 29614114

32. Chang VW, Lauderdale DS. Fundamental cause theory, technological innovation, and health disparities: the case of cholesterol in the era of statins. J Health Soc Behav 2009 Sep;50(3):245–260. doi: 10.1177/002214650905000301 19711804

33. Patient Centered Outcomes Research Institute. Research & Results. https://www.pcori.org/research-results-home Accessed May 29, 2019.

34. Des Jarlais DC, Lyles C, Crepaz N, TREND Group. Improving the reporting quality of nonrandomized evaluations of behavioral and public health interventions: the TREND statement. Am J Public Health 2004 Mar;94(3):361–366. doi: 10.2105/ajph.94.3.361 14998794

35. Lau BD, Shaffer DL, Hobson DB, Yenokyan G, Wang J, Sugar EA, et al. Effectiveness of two distinct web-based education tools for bedside nurses on medication administration practice for venous thromboembolism prevention: A randomized clinical trial. PLoS One 2017 Aug 16;12(8):e0181664. doi: 10.1371/journal.pone.0181664 28813425

36. Follmann D, Proschan M, Leifer E. Multiple outputation: inference for complex clustered data by averaging analyses from independent data. Biometrics 2003 Jun;59(2):420–429. doi: 10.1111/1541-0420.00049 12926727

37. Wong A, Kraus PS, Lau BD, Streiff MB, Haut ER, Hobson DB, et al. Patient preferences regarding pharmacologic venous thromboembolism prophylaxis. J Hosp Med 2015;10(2):108–111. doi: 10.1002/jhm.2282 25418208

38. Shekelle PG, Pronovost PJ, Wachter RM, McDonald KM, Schoelles K, Dy SM, et al. The top patient safety strategies that can be encouraged for adoption now. Ann Intern Med 2013 Mar 5;158(5 Pt 2):365–368. doi: 10.7326/0003-4819-158-5-201303051-00001 23460091

39. Shekelle PG, Wachter RM, Pronovost PJ, Schoelles K, McDonald KM, Dy SM, et al. Making Health Care Safer II: An Updated Critical Analysis of the Evidence for Patient Safety Practices. Evid Rep Technol Assess (Full Rep) 2013;211:1–945.

40. Weaver SJ, Lubomksi LH, Wilson RF, Pfoh ER, Martinez KA, Dy SM. Promoting a culture of safety as a patient safety strategy: a systematic review. Ann Intern Med 2013 Mar 5;158(5 Pt 2):369–374. doi: 10.7326/0003-4819-158-5-201303051-00002 23460092

41. U.S. Department of Health and Human Services, Office of Disease Prevention and Health Promotion. Healthy People 2020 [Internet]. (https://www.healthypeople.gov/2020) Accessed May 29, 2019.

42. Zaitoun A, Al-Najafi S, Musa T, Szpunar S, Light D, Lalonde T, et al. The association of race with quality of health in peripheral artery disease following peripheral vascular intervention: The Q-PAD Study. Vasc Med 2017 Dec;22(6):498–504. doi: 10.1177/1358863X17733065 28980511

43. Haider AH, Ong'uti S, Efron DT, Oyetunji TA, Crandall ML, Scott VK, et al. Association between hospitals caring for a disproportionately high percentage of minority trauma patients and increased mortality: a nationwide analysis of 434 hospitals. Arch Surg 2012 Jan;147(1):63–70. doi: 10.1001/archsurg.2011.254 21930976

44. Cohen MG, Fonarow GC, Peterson ED, Moscucci M, Dai D, Hernandez AF, et al. Racial and ethnic differences in the treatment of acute myocardial infarction: findings from the Get With the Guidelines-Coronary Artery Disease program. Circulation 2010 Jun 1;121(21):2294–2301. doi: 10.1161/CIRCULATIONAHA.109.922286 20479153

45. Finkelstein J, Knight A, Marinopoulos S, Gibbons MC, Berger Z, Aboumatar H, et al. Enabling Patient-Centered Care Through Health Information Technology. 2012;206.

46. United States Census Bureau. 2010 Census U.S. Census Bureau. 2013; http://ftp2.census.gov/. Accessed Oct 18, 2018.


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