Mating strategy is determinant of adenovirus prevalence in European bats

English version

Autoři: Federica Rossetto ^aff001; Maria Iglesias-Caballero ^aff002; H. Christoph Liedtke ^aff001; Ivan Gomez-Mestre ^aff001; Jose M. Berciano ^aff002; Gonzalo Pérez-Suárez ^aff003; Oscar de Paz ^aff003; Carlos Ibáñez ^aff001; Juan E. Echevarría ^aff002; Inmaculada Casas ^aff002; Javier Juste ^aff001
Působiště autorů: Evolutionary Biology Unit, Estación Biológica Doñana (CSIC), Sevilla, Spain ^aff001; National Center of Microbiology, (ISCIII), Madrid, Spain ^aff002; Department of Life Sciences, University of Alcalá, Alcalá de Henares, Madrid, Spain ^aff003; CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain ^aff004
Vyšlo v časopise: PLoS ONE 15(1)
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pone.0226203

Souhrn

Adenoviruses are double-strained DNA viruses found in a great number of vertebrates, including humans. In order to understand their transmission dynamics, it is crucial, even from a human health perspective, to investigate how host traits influence their prevalence. Bats are important reservoirs for adenoviruses, and here we use the results of recent screenings in Western Europe to evaluate the association between characteristic traits of bat species and their probability of hosting adenoviruses, taking into account their phylogenetic relationships. Across species, we found an important phylogenetic component in the presence of adenoviruses and mating strategy as the most determinant factor conditioning the prevalence of adenoviruses across bat species. Contrary to other more stable mating strategies (e.g. harems), swarming could hinder transmission of adenoviruses since this strategy implies that contacts between individuals are too short. Alternatively, bat species with more promiscuous behavior may develop a stronger immune system. Outstandingly high prevalence of adenoviruses was reported for the Iberian species Pipistrellus pygmaeus, P. kuhlii and Nyctalus lasiopterus and we found that in the latter, males were more likely to be infected by adenoviruses than females, due to the immunosuppressing consequence of testosterone during the mating season. As a general trend across species, we found that the number of adenoviruses positive individuals was different across localities and that the difference in prevalence between populations was correlated with their geographic distances for two of the three studied bat species (P. pygmaeus and P.kuhlii). These results increase our knowledge about the transmission mechanisms of adenoviruses.

Klíčová slova:

Adenoviruses – Animal behavior – Bats – Brownian motion – Ebola virus – Europe – Fruit bats – Phylogenetics

Zdroje

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Mating strategy is determinant of adenovirus prevalence in European bats

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