Obstructive sleep apnea and hypopnea syndrome in patients admitted in a tertiary hospital in Cameroon: Prevalence and associated factors
Autoři:
Virginie Poka-Mayap aff001; Dodo Balkissou Adamou aff002; Massongo Massongo aff001; Steve Voufouo Sonwa aff003; Jacqueline Alime aff003; Ben Patrick Michel Moutlen aff003; Alfred Kongnyu Njamnshi aff004; Andre Noseda aff007; Eric Walter Pefura-Yone aff001
Působiště autorů:
Pulmonology Department, Yaounde Jamot Hospital, Yaounde, Cameroon
aff001; Faculty of Medicine of Garoua, The University of Ngaoundere, Garoua, Cameroon
aff002; Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon
aff003; Department of Internal Medicine and Subspecialties, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon
aff004; Department of Neurology, Yaounde Central Hospital, Yaounde, Cameroon
aff005; Brain Research Africa Initiative (BRAIN), Yaounde, Cameroon
aff006; Pulmonology Department, Brugmann University Hospital U.L.B., Brussels, Belgium
aff007
Vyšlo v časopise:
PLoS ONE 15(1)
Kategorie:
Research Article
doi:
https://doi.org/10.1371/journal.pone.0227778
Souhrn
Purpose
Obstructive sleep apnea and hypopnea syndrome (OSAHS) is poorly documented in Sub-Saharan Africa, especially in the hospital setting. The aim of this study was to determine its prevalence and to investigate the associated factors in patients admitted in a tertiary referral hospital in Cameroon.
Methods
In this cross-sectional study conducted in the Cardiology, Endocrinology and Neurology departments of the Yaounde Central Hospital; all patients aged 21 and older were included consecutively. A sample of randomly selected patients was recorded using a portable sleep monitoring device (PMD). OSAHS was defined as apnea-hypopnea index (AHI) ≥ 5/hour (with > 50% of events being obstructive) and moderate to severe OSAHS as an AHI > 15/hour. Logistic regression was used to identify factors associated to OSAHS.
Results
Of the 359 patients included, 202 (56.3%) patients were women. The mean age (standard deviation) was 58 (16) years. The prevalence of OSAHS assessed by PMD (95% CI) was 57.7% (48.5–66.9%), 53.8% in men and 62.7% in women (p = 0.44). The median (25th-75th percentiles) AHI, body mass index and Epworth Sleepiness Scale score of OSAHS patients were 17 (10.6–26.9)/hour, 27.4 (24.7–31.6) kg/m2 and 7 (5–9) respectively. The only factor associated to moderate to severe OSAHS was hypertension [odds ratio (95% CI)]: 3.24 (1.08–9.72), p = 0.036.
Conclusion
OSAHS is a common condition in patients in this health care centre of Cameroon. In the hospital setting, screening for OSAHS in patients with hypertension is recommended.
Klíčová slova:
Alcohol consumption – Body Mass Index – diabetes mellitus – Hypertension – Measurement equipment – Sleep – Sleep apnea – Sleep disorders
Zdroje
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