Incidence, characteristics, and mortality of infective endocarditis in France in 2011
Autoři:
S. Sunder aff001; L. Grammatico-Guillon aff002; A. Lemaignen aff004; M. Lacasse aff004; C. Gaborit aff003; D. Boutoille aff005; P. Tattevin aff006; E. Denes aff007; T. Guimard aff008; M. Dupont aff009; L. Fauchier aff010; L. Bernard aff002
Působiště autorů:
CH de Niort, Service des Maladies Infectieuses et Tropicale, Niort, France
aff001; CHRU de Tours, Unité d’Épidémiologie des données cliniques, EpiDcliC, Tours, France
aff002; Unité Inserm 1259, Université de tours, Tours, France
aff003; CHRU de Tours, Service de Médecine Interne et Maladies Infectieuses, Tours, France
aff004; CHU de Nantes, Service des Maladies Infectieuses et Tropicales, Nantes, France
aff005; CHU de Rennes, Service des Maladies Infectieuses et Réanimation Médicale, Rennes, France
aff006; CHU de Limoges, Service des Maladies Infectieuses et Tropicales, Limoges, France
aff007; CH de La Roche sur Yon, Service des Maladies Infectieuses, La Roche sur Yon, France
aff008; CH de Saint Malo, Service des Maladies Respiratoires et Infectieuses, Saint Malo, France
aff009; Equipe d’accueil EA 1275, Université de Tours, Tours, France
aff010; CHRU de Tours, Service de cardiologie, Tours, France
aff011
Vyšlo v časopise:
PLoS ONE 14(10)
Kategorie:
Research Article
doi:
https://doi.org/10.1371/journal.pone.0223857
Souhrn
Objectives
We assessed the determinants of mortality in infective endocarditis (IE), using the national hospital discharge databases (HDD) in 2011.
Methods
IE stays were extracted from the national HDD, with a definition based on IE-related diagnosis codes. This definition has been assessed according to Duke criteria by checking a sample of medical charts of IE giving a predictive positive value of 86.1% (95% confidence interval (CI): 82.7% - 89.5%). The impact of heart valve surgery on survival has been studied if performed during the initial stay, and over the year of follow-up. Risk factors of in-hospital mortality were identified using logistic regression model for the initial stay and Cox Time-dependent model for the 1-year mortality.
Results
The analysis included 6,235 patients. The annual incidence of definite IEs was 63 cases/million residents. Staphylococci and Streptococci were the most common bacteria (44% and 45%, respectively). A valvular surgery was performed in 20% of cases, but substantial variations existed between hospitals. The in-hospital mortality was 21% (ranging 12% to 27% according to the region of patients), associated with age>70, chronic liver disease, renal failure, S. aureus, P. aeruginosa or candida infection and strokes whereas valvular surgery, a native valve IE or intraveinous drug use (right heart IE) were significantly protective for an initial death. The same factors were associated with the one-year mortality, except for valvular surgery which was associated with a 1.4-fold higher risk of death during the year post IE.
Conclusion
We reported a high IE incidence rate. Valvular surgery was considerably less frequent in this study than in the previous published data (near 50%) whereas mortality was similar. Surgery was associated with higher survival if undergone within the initial stay. There were significant regional differences in frequency of surgery but it did not impact mortality.
Klíčová slova:
Cardiac surgery – Epidemiology – France – Hospitals – Ischemic stroke – Staphylococcus aureus – Streptococcus – Surgical and invasive medical procedures
Zdroje
1. Habib G, Hoen B, Tornos P, Thuny F, Prendergast B, Vilacosta I, et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J. 2009;30: 2369–2413. doi: 10.1093/eurheartj/ehp285 19713420
2. Selton-Suty C, Célard M, Le Moing V, Doco-Lecompte T, Chirouze C, Iung B, et al. Preeminence of Staphylococcus aureus in infective endocarditis: a 1-year population-based survey. Clin Infect Dis. 2012;54: 1230–1239. doi: 10.1093/cid/cis199 22492317
3. Hoen B, Duval X. Clinical practice. Infective endocarditis. N Engl J Med. 2013;368: 1425–1433. doi: 10.1056/NEJMcp1206782 23574121
4. Dzupova O, Machala L, Baloun R, Maly M, Benes J, Czech Infective Endocarditis Working Group. Incidence, predisposing factors, and aetiology of infective endocarditis in the Czech Republic. Scand J Infect Dis. 2012;44: 250–255. doi: 10.3109/00365548.2011.632643 22122645
5. Dayer MJ, Jones S, Prendergast B, Baddour LM, Lockhart PB, Thornhill MH. Incidence of infective endocarditis in England, 2000–13: a secular trend, interrupted time-series analysis. Lancet. 2015;385: 1219–1228. doi: 10.1016/S0140-6736(14)62007-9 25467569
6. Fedeli U, Schievano E, Buonfrate D, Pellizzer G, Spolaore P. Increasing incidence and mortality of infective endocarditis: a population-based study through a record-linkage system. BMC Infect Dis. 2011;11: 48. doi: 10.1186/1471-2334-11-48 21345185
7. Cresti A, Chiavarelli M, Scalese M, Nencioni C, Valentini S, Guerrini F, et al. Epidemiological and mortality trends in infective endocarditis, a 17-year population-based prospective study. Cardiovasc Diagn Ther. 2017;7: 27–35. doi: 10.21037/cdt.2016.08.09 28164010
8. Walls G, McBride S, Raymond N, Read K, Coomarasamy C, Morris AJ, et al. Infective endocarditis in New Zealand: data from the International Collaboration on Endocarditis Prospective Cohort Study. N Z Med J. 2014;127: 38–51.
9. Olmos C, Vilacosta I, Fernández-Pérez C, Bernal JL, Ferrera C, García-Arribas D, et al. The Evolving Nature of Infective Endocarditis in Spain: A Population-Based Study (2003 to 2014). J Am Coll Cardiol. 2017;70: 2795–2804. doi: 10.1016/j.jacc.2017.10.005 29191329
10. Østergaard L, Oestergaard LB, Lauridsen TK, Dahl A, Chaudry M, Gislason G, et al. Long-term causes of death in patients with infective endocarditis who undergo medical therapy only or surgical treatment: a nationwide population-based study. Eur J Cardiothorac Surg. 2018;54: 860–866. doi: 10.1093/ejcts/ezy156 29648662
11. DeSimone DC, Tleyjeh IM, Correa de Sa DD, Anavekar NS, Lahr BD, Sohail MR, et al. Incidence of Infective Endocarditis Due to Viridans Group Streptococci Before and After the 2007 American Heart Association’s Prevention Guidelines: An Extended Evaluation of the Olmsted County, Minnesota, Population and Nationwide Inpatient Sample. Mayo Clin Proc. 2015;90: 874–881. doi: 10.1016/j.mayocp.2015.04.019 26141329
12. Pant S, Patel NJ, Deshmukh A, Golwala H, Patel N, Badheka A, et al. Trends in infective endocarditis incidence, microbiology, and valve replacement in the United States from 2000 to 2011. J Am Coll Cardiol. 2015;65: 2070–2076. doi: 10.1016/j.jacc.2015.03.518 25975469
13. Keller K, von Bardeleben RS, Ostad MA, Hobohm L, Munzel T, Konstantinides S, et al. Temporal Trends in the Prevalence of Infective Endocarditis in Germany Between 2005 and 2014. Am J Cardiol. 2017;119: 317–322. doi: 10.1016/j.amjcard.2016.09.035 27816113
14. Sunder S, Grammatico-Guillon L, Baron S, Gaborit C, Bernard-Brunet A, Garot D, et al. Clinical and economic outcomes of infective endocarditis. Infect Dis (Lond). 2015;47: 80–87. doi: 10.3109/00365548.2014.968608 25426997
15. Duval X, Delahaye F, Alla F, Tattevin P, Obadia J-F, Le Moing V, et al. Temporal trends in infective endocarditis in the context of prophylaxis guideline modifications: three successive population-based surveys. J Am Coll Cardiol. 2012;59: 1968–1976. doi: 10.1016/j.jacc.2012.02.029 22624837
16. Grammatico-Guillon L, Baron S, Gettner S, Lecuyer A-I, Gaborit C, Rosset P, et al. Bone and joint infections in hospitalized patients in France, 2008: clinical and economic outcomes. J Hosp Infect. 2012;82: 40–48. doi: 10.1016/j.jhin.2012.04.025 22738613
17. Grammatico L, Baron S, Rusch E, Lepage B, Surer N, Desenclos JC, et al. Epidemiology of vertebral osteomyelitis (VO) in France: analysis of hospital-discharge data 2002–2003. Epidemiol Infect. 2008;136: 653–660. doi: 10.1017/S0950268807008850 17568478
18. Grammatico-Guillon L, Baron S, Gaborit C, Rusch E, Astagneau P. Quality assessment of hospital discharge database for routine surveillance of hip and knee arthroplasty-related infections. Infect Control Hosp Epidemiol. 2014;35: 646–651. doi: 10.1086/676423 24799640
19. CLARTE. Consortium Loire-Atlantique-Aquitaine-Rhône-Alpes pour la production d’indicateurs de qualité en sanTE [Internet]. [cited 16 Dec 2013]. Available: http://clarte-sante.fr/
20. Iversen K, Ihlemann N, Gill SU, Madsen T, Elming H, Jensen KT, et al. Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis. N Engl J Med. 2019;380: 415–424. doi: 10.1056/NEJMoa1808312 30152252
21. Slipczuk L, Codolosa JN, Davila CD, Romero-Corral A, Yun J, Pressman GS, et al. Infective endocarditis epidemiology over five decades: a systematic review. PLoS ONE. 2013;8: e82665. doi: 10.1371/journal.pone.0082665 24349331
22. Ursi MP, Durante Mangoni E, Rajani R, Hancock J, Chambers JB, Prendergast B. Infective Endocarditis in the Elderly: Diagnostic and Treatment Options. Drugs Aging. 2019;36: 115–124. doi: 10.1007/s40266-018-0614-7 30488173
23. Gavazzi G, Krause K-H. Ageing and infection. Lancet Infect Dis. 2002;2: 659–666. 12409046
24. Yoshikawa TT. Perspective: aging and infectious diseases: past, present, and future. J Infect Dis. 1997;176: 1053–1057. doi: 10.1086/516547 9333166
25. Forestier E, Fraisse T, Roubaud-Baudron C, Selton-Suty C, Pagani L. Managing infective endocarditis in the elderly: new issues for an old disease. Clin Interv Aging. 2016;11: 1199–1206. doi: 10.2147/CIA.S101902 27621607
26. Sadighi Akha AA. Aging and the immune system: An overview. J Immunol Methods. 2018;463: 21–26. doi: 10.1016/j.jim.2018.08.005 30114401
27. Kang D-H. Timing of surgery in infective endocarditis. Heart. 2015;101: 1786–1791. doi: 10.1136/heartjnl-2015-307878 26285598
28. Cuervo G, Rombauts A, Caballero Q, Grau I, Pujol M, Ardanuy C, et al. Twenty-Year Secular Trends in Infective Endocarditis in a Teaching Hospital. Open Forum Infect Dis. 2018;5: ofy183. doi: 10.1093/ofid/ofy183 30167435
29. Murdoch DR, Corey GR, Hoen B, Miró JM, Fowler VG, Bayer AS, et al. Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis–Prospective Cohort Study. Archives of internal medicine. 2009;169: 463–473. doi: 10.1001/archinternmed.2008.603 19273776
30. Miro JM, Anguera I, Cabell CH, Chen AY, Stafford JA, Corey GR, et al. Staphylococcus aureus native valve infective endocarditis: report of 566 episodes from the International Collaboration on Endocarditis Merged Database. Clin Infect Dis. 2005;41: 507–514. doi: 10.1086/431979 16028160
31. Sy RW, Kritharides L. Health care exposure and age in infective endocarditis: results of a contemporary population-based profile of 1536 patients in Australia. Eur Heart J. 2010;31: 1890–1897. doi: 10.1093/eurheartj/ehq110 20453066
32. Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta J-P, Del Zotti F, et al. 2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). Eur Heart J. 2015;36: 3075–3128. doi: 10.1093/eurheartj/ehv319 26320109
33. Yombi JC, Yuma SN, Pasquet A, Astarci P, Robert A, Rodriguez HV. Staphylococcal versus Streptococcal infective endocarditis in a tertiary hospital in Belgium: epidemiology, clinical characteristics and outcome. Acta Clin Belg. 2017;72: 417–423. doi: 10.1080/17843286.2017.1309341 28372481
34. Pazdernik M, Kautzner J, Sochman J, Kettner J, Vojacek J, Pelouch R. Clinical manifestations of infective endocarditis in relation to infectious agents: An 8-year retrospective study. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2016;160: 298–304. doi: 10.5507/bp.2015.062 26740050
35. N’Guyen Y, Duval X, Revest M, Saada M, Erpelding M-L, Selton-Suty C, et al. Time interval between infective endocarditis first symptoms and diagnosis: relationship to infective endocarditis characteristics, microorganisms and prognosis. Ann Med. 2017;49: 117–125. doi: 10.1080/07853890.2016.1235282 27607562
36. Rhee C, Gohil S, Klompas M. Regulatory mandates for sepsis care—reasons for caution. N Engl J Med. 2014;370: 1673–1676. doi: 10.1056/NEJMp1400276 24738642
Článek vyšel v časopise
PLOS One
2019 Číslo 10
- S diagnostikou Parkinsonovy nemoci může nově pomoci AI nástroj pro hodnocení mrkacího reflexu
- Je libo čepici místo mozkového implantátu?
- Pomůže v budoucnu s triáží na pohotovostech umělá inteligence?
- AI může chirurgům poskytnout cenná data i zpětnou vazbu v reálném čase
- Nová metoda odlišení nádorové tkáně může zpřesnit resekci glioblastomů
Nejčtenější v tomto čísle
- Correction: Low dose naltrexone: Effects on medication in rheumatoid and seropositive arthritis. A nationwide register-based controlled quasi-experimental before-after study
- Combining CDK4/6 inhibitors ribociclib and palbociclib with cytotoxic agents does not enhance cytotoxicity
- Experimentally validated simulation of coronary stents considering different dogboning ratios and asymmetric stent positioning
- Risk factors associated with IgA vasculitis with nephritis (Henoch–Schönlein purpura nephritis) progressing to unfavorable outcomes: A meta-analysis
Zvyšte si kvalifikaci online z pohodlí domova
Všechny kurzy