The effect of heavy metal contamination on humans and animals in the vicinity of a zinc smelting facility
Autoři:
Xiaoyun Shen aff001; Yongkuan Chi aff002; Kangning Xiong aff002
Působiště autorů:
School of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, China
aff001; State Engineering Technology Institute for Karst Desertification Control, Guizhou Normal University, Guiyang, China
aff002; World Bank Poverty Alleviation Project Office in Guizhou, Southwest China, Guiyang, China
aff003
Vyšlo v časopise:
PLoS ONE 14(10)
Kategorie:
Research Article
doi:
https://doi.org/10.1371/journal.pone.0207423
Souhrn
A diagnosis of heavy metal poisoning in sheep living on pastures in the vicinity of a smelting facility in the Wumeng mountain area of China was based on laboratory tests and clinical symptoms. Furthermore, heavy metal contamination in the food chain was found to have a deleterious effect on the health of local residents. The levels of copper(Cu), zinc(Zn), cadmium (Cd), and lead (Pb) in irrigation water, soil, forages, and animal tissues were measured in samples taken from the vicinity of a smelting facility and control samples. Heavy metal contents in food (corn, rice, and wheat), as well as in human tissues (blood and hair) obtained from local residents were also determined. Hematological values were also determined in human and animal samples. The content of Cu, Zn, Cd, and Pb in irrigation water, soils, and forages were markedly higher in affected areas than in samples from healthy pastures. Concentrations of Cd and Pb were 177.82 and 16.61 times greater in forages than controls, respectively, and 68.71 and 15.66 times greater in soils than controls, respectively. The heavy metal content in food (corn, rice, and wheat) from affected areas was markedly higher than in the control samples. Cd and Pb content in the tissues of affected sheep were markedly higher than in control animals (P < 0.01), while concentrations of Cd and Pb in blood and hair samples from local residents were markedly higher than in control samples (P < 0.01). The occurrence of anemia in affected humans and animals followed a hypochromic and microcytic pattern. The intake of Cd and Pb was estimated according to herbage ingestion rates. It was found that the levels of Cd and Pb which accumulated in sheep through the ingestion of vegetation growing in the sites closest to the smelter were approximately 3.36 and 38.47 mg/kg body wt./day, respectively. Such levels surpassed the fatal dosages for sheep of 1.13 mg Cd/kg body wt/day and 4.42 mg Pb/kg body wt./day. The serum total antioxidant capacity in affected humans and animals was significantly lower than in the controls (P < 0.01). Serum protein parameters in affected humans and animals were significantly reduced (P < 0.01); therefore, it was concluded that heavy metal contamination caused harm to sheep, and also posed a significant risk to humans living in the vicinity of the zinc smelting facility.
Klíčová slova:
Blood – Heavy metals – Livestock – Manganese – Metallic lead – Sheep – Zinc – Copper
Zdroje
1. Liao JJ, Shen XY, Huo B, Xiong KN. Effect of nitrogenous fertilizer on the antioxidant systems of Wumeng semi-fine wool sheep in the Karst mountain areas. Acta Prataculturae Sinica.2018; 27(1):169–176.
2. Shen XY, Chi YK, Huo B, Wu T, Xiong KN. Effect of fertilization on ryegrass quality and mineral metabolism in grazing the Wumeng semi-fine wool sheep. Fresen Environ. Bull. 2018; 26 (10): 6824–6830.
3. Benson NU, Asuquo FE, Williams AB, Essien JP, Ekong CI, Akpabio O, et al. Source evaluation and trace metal contamination in benthic sediments from equatorial ecosystems using multivariate statistical techniques. Plos One. 2016; 11(6), e0156485. doi: 10.1371/journal.pone.0156485 27257934
4. Willscher S, Jablonski L, Fona Z, Rahmi R, Wittig J. Phytoremediation experiments with helianthus tuberosus under different pH and heavy metal soil concentrations. Hydrometallurgy. 2017; 168(3), 153–158.
5. Ciazela J, Siepak M, Wojtowicz P. Tracking heavy metal contamination in a complex river-oxbow lake system: Middle Odra Valley, Germany/Poland. Sci. Total. Environ.2018; 616(11), 996–1006.
6. Casalino E, Calzaretti G, Sblano C, Landriscina C. Molecular inhibitory mechanisms of antioxidant enzymes in rat liver and kidney by cadmium. Toxicology.2002; 179, 37–50. doi: 10.1016/s0300-483x(02)00245-7 12204541
7. Zhang G, Bai J, Zhao Q, Jia J, Wen X. Heavy metals pollution in soil profiles from seasonal-flooding riparian wetlands in a Chinese delta: Levels, distributions and toxic risks. Phys. Chem. Earth.2017; 97(2): 54–61.
8. Greaves WW, Rom WN, Lyon JL, Varley G, Wright DD, Chiu G. Relationship between lung cancer and distance of residence from nonferrous smelter stack effluent. Am. J. Ind. Med.2010; 2(1), 15–23.
9. Gąsiorek M, Kowalska J, Mazurek R, Pająk M. Comprehensive assessment of heavy metal pollution in topsoil of historical urban park on an example of the Planty Park in Krakow (Poland). Chemosphere.2017; 179(11),148–158.
10. Latif R, Malek M, Mirmonsef H. Cadmium and lead accumulation in three endogeic earthworm species. Bull. Environ. Contam. Toxicol. 2013; 90(4), 456–459. doi: 10.1007/s00128-012-0941-z 23283534
11. Ramachandra TV, Sudarshan PB, Mahesh MK, Vinay S. Spatial patterns of heavy metal accumulation in sediments and macrophytes of bellandur wetland, bangalore. J. Environ. Manage. 2018; 206(7), 1204–1210.
12. Shin W, Choung S, Han WS, Hwang J, Kang G. Evaluation of multiple prps’ contributions to soil contamination in reclaimed sites around an abandoned smelter. Sci. Total Environ. 2018; 642, 314–321. doi: 10.1016/j.scitotenv.2018.06.031 29906722
13. USA, National Research Council, Subcommittee on Mineral Toxicity in Animals. Mineral tolerance of domestic animals. National Academy of Sciences. 2018; 193–196.
14. Shen XY, Zhang RD. Studies on "stiffness of extremities disease" in the yak (bos mutus). J. Wildlife. Dis. 2012; 48(3), 542–547.
15. Satarug S, Baker JR, Urbenjapol S, Haswellelkins M, Reilly PE, Williams DJ, et al. A global perspective on cadmium pollution and toxicity in non-occupationally exposed population. Toxicol. Lett. 2003; 137(1), 65–83.
16. Steindor KA, Franiel IJ, Bierza WM, Pawlak B, Palowski BF. Assessment of heavy metal pollution in surface soils and plant material in the post-industrial city of katowice, poland. Environ. Lett. 2016; 51(5), 371–379.
17. Salmela S, Vuori E, Kilpi ÖJO. The effect of washing procedures on trace element content of human hair. Anal. Chim. Acta. 1981; 125(01), 131–137.
18. Shen XY, Du GZ, Li H. Studies of a naturally occurring molybdenum-induced copper deficiency in the yak. Vet. J. 2006; 171(2), 352–357. doi: 10.1016/j.tvjl.2004.11.006 16490720
19. Shen XY. Effect of nitrogenous fertilizer treatment on mineral metabolism in grazing yaks. Agr. Sci. China. 2009; 8(3), 361–368.
20. Shen XY, Zhang J.H, Zhang RD. Phosphorus metabolic disorder of Guizhou semi-fine wool sheep. Plos One. 2014; 9(2), e89472. doi: 10.1371/journal.pone.0089472 24586803
21. Xie Y, Chen TB, Lei M, Yang J, Guo QJ, Song B, et al. Spatial distribution of soil heavy metal pollution estimated by different interpolation methods: accuracy and uncertainty analysis. Chemosphere. 2011; 82(3), 468–476. doi: 10.1016/j.chemosphere.2010.09.053 20970158
22. Kapusta P, Łukasz S. Effects of heavy metal pollution from mining and smelting on enchytraeid communities under different land management and soil conditions. Sci. Total Environ. 2015; 536(1), 517–526.
23. Tang W, Zhang W, Zhao Y, Zhang H, Shan B. Basin-scale comprehensive assessment of cadmium pollution, risk, and toxicity in riverine sediments of the haihe basin in north china. Ecol. Indic. 2017; 81, 295–301.
24. Tella M, Bravin MN, Thuriã SL, Cazevieille P, Chevassus-Rosset C, Collin B.,et al. Increased zinc and copper availability in organic waste amended soil potentially involving distinct release mechanisms. Environ. Poll. 2016; 212, 299–306.
25. Berglund M, Akesson A, Bjellerup P, Vahter M. Metal-bone interactions. Toxicol. Lett. 2000; 112(113), 219–225.
26. Norouzi S, Khademi H, Cano AF, Acosta JA. Biomagnetic monitoring of heavy metals contamination in deposited atmospheric dust, a case study from Isfahan, Iran. J. Environ. Manage. 2016; 173(10), 55–64.
27. Olawoyin R, Schweitzer L, Zhang K, Okareh O, Slates K. Index analysis and human health risk model application for evaluating ambient air-heavy metal contamination in chemical valley sarnia. Ecotox. Environ. Safe. 2018; 148, 72–81.
28. Hong S, Candelone JP, Patterson CC, Boutron CF. History of ancient copper smelting pollution during roman and medieval times recorded in green land ice. Science.1669; 272(5259), 246–249.
29. Edwards JR, Prozialeck WC. Cadmium, diabetes and chronic kidney disease. Toxicol. Appl. Pharmacol. 2009; 238(3), 289–293. doi: 10.1016/j.taap.2009.03.007 19327375
30. Hambach R, Lison D, D’Haese P, Weyler J, François G, Schryver AD, et al. Adverse effects of low occupational cadmium exposure on renal and oxidative stress biomarkers in solderers. Occup. Environ. Med. 2013; 70(2), 108–113. doi: 10.1136/oemed-2012-100887 23104735
31. Huang Y, Chen Q, Deng M, Japenga J, Li T, Yang X, et al. Heavy metal pollution and health risk assessment of agricultural soils in a typical peri-urban area in southeast china. J. Environ. Manage. 2018; 207, 159–168. doi: 10.1016/j.jenvman.2017.10.072 29174991
32. Brun LA, Maillet J, Hinsinger P, Pépin M. Evaluation of copper availability to plants in copper-contaminated vineyard soils. Environ. Pollut. 2001; 111(2), 293–302. doi: 10.1016/s0269-7491(00)00067-1 11202733
33. Hu H, Rothenberg S, Schwartz BS. The epidemiology of lead toxicity in adults: measuring dose and consideration of other methodologic issues. Environ. Health. Persp. 2007; 115(3), 455–462.
34. Hussain T, Shukla GS, Chandra SV. Effects of cadmium on superoxide dismutase and lipid peroxidation in liver and kidney of growing rats: in vivo and in vitro studies. Pharmacol. Toxico. 1987; 60(5), 355–358.
35. Elmissiry MA, Shalaby F. Role of β-carotene in ameliorating the cadmium-induced oxidative stress in rat brain and testis. J. Biochem. Mol. Toxic. 2000; 14(5), 238–243.
36. Obida CB, Alan GB, Duncan JW, Semple KT. Quantifying the exposure of humans and the environment to oil pollution in the niger delta using advanced geostatistical techniques. Environ. Int. 2018; 111, 32–42. doi: 10.1016/j.envint.2017.11.009 29169077
37. Regoli F, Principato G. Glutathione, glutathione-dependent and antioxidant enzymes in mussel, mytilus galloprovincialis, exposed to metals under field and laboratory conditions: implications for the use of biochemical biomarkers. Aquat. Toxicol. 1995; 31(2), 143–164.
38. Sazuka Y, Tanizawa H, Takino Y. Effect of adriamycin on the activities of superoxide dismutase, glutathione peroxidase and catalase in tissues of mice. Jpn. J. Cancer Res. 1989; 80(1), 89–94. doi: 10.1111/j.1349-7006.1989.tb02250.x 2496064
39. Khalid S, Shahid M, Niazi NK, Murtaza B, Bibi I, Dumat C. A comparison of technologies for remediation of heavy metal contaminated soils. J. Geochem. Explor. 2017; 247–268.
40. Jacob JM, Karthik C, Saratale RG, Kumar SS, Prabakar D. Kadirvelu K, Pugazhendhi A. Biological approaches to tackle heavy metal pollution: a survey of literature. J. Environ. Manage. 2018; 217, 56–70. doi: 10.1016/j.jenvman.2018.03.077 29597108
41. Suttle NF. The mineral nutrition of livestock. 4th ed. CABI Publishing Cambridge, USA; 2010. pp. 255–459.
42. Dehury B, Sarma K, Sarmah R, Sahu J. In silico analyses of superoxide dismutases (SODs) of rice (Oryza sativa L.). J. Plant Biochem. Biotechnol, 2013; 22(1):150–156.
43. Filiz E, Koc I, Ozyigit II. Comparative Analysis and Modeling of Superoxide Dismutases (SODs) in Brachypodium distachyon L, 2014; 173(5):1183–1196.
44. Gracjana L, Trzebuniak K F, Paulina Z P. The activity of superoxide dismutases (SODs) at the early stages of wheat deetiolation. PLOS ONE, 2018;13(3):e0194678. doi: 10.1371/journal.pone.0194678 29558520
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