Knowledge, beliefs, and concerns about bone health from a systematic review and metasynthesis of qualitative studies
Authors:
Jude des Bordes aff001; Seema Prasad aff002; Greg Pratt aff003; Maria E. Suarez-Almazor aff001; Maria A. Lopez-Olivo aff001
Authors place of work:
Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
aff001; Department of Gastroenterology Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
aff002; Research Medical Library, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
aff003
Published in the journal:
PLoS ONE 15(1)
Category:
Research Article
doi:
https://doi.org/10.1371/journal.pone.0227765
Summary
Background
Patients with low bone density or osteoporosis need information for effective prevention or disease management, respectively. However, patients may not be getting enough information from their primary care providers or other sources. Inadequate disease information leaves patients ill-informed and creates misconceptions and unnecessary concerns about the disease.
Objective
We systematically reviewed and synthesized the available literature to determine patient knowledge, beliefs, and concerns about osteoporosis and identify potential gaps in knowledge.
Methods
A systematic search was conducted for full-text qualitative studies addressing understanding, literacy, and/or perceptions about osteoporosis and its management, using Medline, EMBASE, Web of Science, Cochrane Library, CINAHL, ERIC, PsychINFO, Psyc Behav Sci Collec, and PubMed, from inception through September 2016. Studies were selected by two reviewers, assessed for quality, and themes extracted using the Joanna Briggs Institute data extraction tool. Thematic analysis was used to identify themes and subthemes.
Results
Twenty-five studies with a total of 757 participants (including 105 men) were selected for analysis out of 1031 unique citations. Selected studies were from Australia, Canada, Denmark, Norway, the United Kingdom, and the United States. Four main themes emerged: inadequate knowledge, beliefs and misconceptions, concerns about osteoporosis, and lack of information from health care providers. Participants had inadequate knowledge about osteoporosis and were particularly uninformed about risk factors, causes, treatment, and prevention. Areas of concern for participants included diagnosis, medication side effects, and inadequate information from primary care providers.
Conclusion
Although there was general awareness of osteoporosis, many misconceptions and concerns were evident. Education on bone health needs to reinforce areas of knowledge and address deficits, misconceptions, and concerns.
Keywords:
Health care providers – Qualitative studies – Health education and awareness – Database searching – Bone density – Primary care – Bone fracture – osteoporosis
Introduction
Osteoporosis is a systemic bone condition characterized by low bone mass and deterioration of the microarchitecture of bone tissue, resulting in increased fragility and an enhanced propensity to fracture [1]. The World Health Organization (WHO) operationally defines osteoporosis as bone mineral density of more than 2.5 standard deviations below the young adult mean value [2].
About 54 million Americans are estimated to have low bone mass and thus have an increased risk of fractures [3]. Osteoporotic fractures have a substantial deleterious impact on quality of life, causing pain, restriction of mobility, and depression; mortality rates after osteoporotic hip or vertebral fractures are increased [3]. Low bone mass is estimated to be responsible for over 1.5 million fractures each year in the United States, resulting in 500,000 hospitalizations and nearly 200,000 nursing home placements, at an estimated cost of about $19 billion [4]. This cost is projected to rise about 50% by 2025 [5].
Prevention is key in the control of osteoporosis and its associated fragility fractures. Successful prevention strategies depend on patients’ knowledge and self-efficacy, which work together to affect healthful behavioral modification. Numerous individual qualitative and mixed-methods studies report on knowledge and attitudes about osteoporosis, therefore, we undertook a systematic review of the existing qualitative literature to synthetize the evidence and identify the gaps in knowledge that must be addressed in educational tools on bone health. We used a metasynthesis approach to gain a deeper understanding and insight into patients’ knowledge, beliefs and concerns.
Methods
The manuscript was prepared according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement (S1 Table) [6].
Eligibility criteria
We included all full-text qualitative research papers written in English and addressing understanding, literacy, and/or perceptions about low bone density or osteoporosis and its management. Manuscripts that employed a mixed methods design with a substantial qualitative component addressing the study objectives were also included. We excluded studies in which participants were less than 18 years old or in which issues of bone health literacy, concerns, and/or perceptions were not addressed, as well as studies for which only abstracts were available.
Information sources and search
A systematic literature search was performed by a medical librarian (G.P.) using search terms related to low bone density and osteoporosis in electronic databases including Medline, EMBASE, Web of Science, Cochrane Library, CINAHL, PschINFO, Psc Behav Sci Collec, and PubMed, from inception to September 2016 (S2 Table).
Study selection
Two reviewers (J.d.B., S.P.) independently screened the manuscripts using the titles and abstracts to exclude studies that were not qualitative or mixed methods studies or did not address knowledge and attitudes on low bone density or osteoporosis. Disagreements were resolved by consensus. Full-text articles of the selected papers were retrieved and assessed.
Data collection process and data items
Findings from the included primary studies in the form of themes or conclusions made by the authors were abstracted into the Joanna Briggs Institute (JBI)-QARI extraction tool [7] by one reviewer (S.P.) and crosschecked by another (J.d.B.). We collected general study characteristics (i.e., authors, year of publication, number of participants, eligibility criteria, age, and synthesis methods) and findings from individual studies, including aspects of low bone health literacy, knowledge of osteoporosis, beliefs, misconceptions, and concerns about being diagnosed and/or living with osteoporosis.
Quality appraisal
Papers that met the inclusion criteria were critically appraised for study quality using the JBI appraisal tool [7] independently by two reviewers (J.d.B., S.P.). This tool assesses studies in 10 domains, evaluating congruity among the variables of philosophical position used in the study, study methodology, study methods, data representation, and results interpretation. In addition, the JBI tool assesses the degree to which the researchers make their biases explicit. It also assesses the relationship between what participants are reported to have said and the conclusions drawn. For each domain, an item is appraised as “Yes” if present, “No” if absent, “Unclear” if uncertain, and “Not Applicable” where it does not apply. Results for each of the assessed domains were summarized.
Synthesis of results
We used a standard metasynthesis approach as described by JBI [7]. The findings were categorized and synthesized using thematic content analysis into themes and sub-themes by one reviewer (J.d.B.) and verified by a second (M.L.-O.). Significant quotes were then tabulated and analyzed in the context of the type of population included in the studies (i.e., studies including only men compared with studies including only women, studies including only people diagnosed with osteoporosis compared with studies including people without an osteoporosis diagnosis, and studies with participants younger than 55 years compared with studies including those aged 55 years or older).
Results
Study selection
Fig 1 is a flow diagram of the selection of articles for inclusion in the study. A total of 1031 unique citations were identified through the search of online databases. Nine hundred sixty-three studies were excluded after review of titles and abstracts. Sixty-eight studies were selected for retrieval. Of these selected studies, 43 were excluded because they fulfilled one or more of the exclusion criteria (S1 File); 25 studies were ultimately included in the metasynthesis [8–32].
Study characteristics and participants
A summary of the characteristics of studies included in the metasynthesis is shown in Table 1. The included studies were conducted in Australia, Canada, Denmark, Norway, the United Kingdom, and the United States. Sample size for included studies ranged from 5 to 173. The studies involved a total of 757 participants, 105 (13.9%) of whom were men. Two studies had only male participants [19, 29], and six studies had both male and female participants but the men were in the minority [9, 11, 14, 18, 26, 27]. Three hundred and eighty-nine (51.4%) participants, including 336 women and 53 men, had a history of osteoporosis or low bone density. Thirteen of the studies included participants diagnosed with osteoporosis or low bone density [10, 14–20, 23, 24, 28, 29, 31], and three comprised patients with a history of osteoporosis-related fractures [12, 26, 27]. Three hundred and eigthy-nine (389, [48.6%]) were healthy volunteers or adults in a community living setting with unknown bone health status [8, 9, 11, 13, 21, 22, 25, 30, 32]. The age of participants ranged from 30 to 90 years.
Quality appraisal
Fig 2 summarizes the final quality assessment of the included studies. Items frequently lacking supporting information to judge quality in the included studies were congruity between the stated philosophical perspective and the research methodology (75.0% of studies), statement locating the researcher culturally or theoretically (66.2%), and influence of the research on the researcher (54.2%). S3 Table shows the individual quality scores for each study. One paper, which was a mixed methods study, was excluded from the quality appraisal [12].
Synthesis of results
One hundred sixteen findings were abstracted from the included studies and grouped into subthemes. The subthemes were classified into four major themes: inadequate knowledge (i.e., definition and disease course [8–11, 13, 15, 23, 29, 31], risk factors and prevention [9, 11, 13, 20, 21, 26, 27], diagnosis and treatment [11, 16, 17, 26, 27, 29]), beliefs and misconceptions (i.e., etiology, presentation, and perceived seriousness [9, 15, 17, 19, 21, 24–28, 30, 31], perceived personal risk [8, 10–12, 17, 18, 22, 24–26, 28], concerns about osteoporosis (i.e., fear of dependence [9, 10, 14, 20, 24, 27], implications of diagnosis [17, 19, 22, 25, 27], medications [10, 11, 16, 17, 25]), and lack of information from health care providers [9, 10, 14, 20, 28, 29].
Inadequate knowledge
Broad knowledge about osteoporosis was common among participants included in the individual studies. However, knowledge of many aspects of the condition was inadequate. Many understood isolated concepts but few had a good understanding of the disease. Knowledge of osteoporosis among participants in 15 included studies was categorized into three subthemes: definition and disease course, risk factors and prevention, and diagnosis and treatment. These subthemes described participants’ understanding of osteoporosis, its risk factors, diagnosis and treatment of the disease, and how it could be prevented. Some participants were simply not interested because they did not see the relevance of osteoporosis to themselves.
Definition and disease course – Both men and women knew of osteoporosis. Many participants associated it with weakness of the bones, reduced bone mineral density, and “porousness of bone” or “brittle bone” in elderly people. Some participants in the studies were insecure about their knowledge of osteoporosis and felt that they knew too little about the condition. In some instances, participants confused arthritis with osteoporosis, ascribing joint pain to osteoporosis. Many informants knew that it was a chronic disease but were unsure whether it would advance or improve over their life course.
Risk factors and prevention – Some participants in the studies associated osteoporosis with aging, menopause, lack of physical activity, poor nutrition, medications, and family history of osteoporosis. Use of calcium supplements and exercise were known to some participants to be preventive. However, others were uncertain about the types of supplements required, their recommended doses and duration of treatment, or their effectiveness. Some participants understood that low bone mineral density predisposed one to a future fracture.
Diagnosis and treatment – Diagnosis of osteoporosis among participants in the studies was usually made when they presented with back or hip pain, through bone health screening, or following a minimal-trauma fracture. Some participants initiated the diagnostic process on their own after obtaining information on the disease from family, friends, or other sources. There was a lack of clarity about the use of the dual-energy x-ray absorptiometry scan and what the results indicated. Some participants were unclear about the types of medications available and how they worked. In some cases, participants familiar with bisphosphonates for the prevention of osteoporosis were uncertain whether the medication might also help with pain. Others sought alternative care such as chiropractic manipulation, physical therapy, and massage for pain after injury.
Beliefs and misconceptions
There were misconceptions about many aspects of the disease. Participants’ beliefs and misconceptions of 18 included studies were categorized into two subthemes: etiology, presentation, and perceived seriousness, and perceived personal risk.
Etiology, presentation, and perceived seriousness – There was a notion among some participants that osteoporosis was caused by stressful life conditions and unexpressed emotional pain such as sadness and depression. Their image of a person with osteoporosis was one of an old woman with a “bent body and a collapsing back” who had developed the condition through leading a difficult and physically demanding life. Although it was generally expected that collapse of the vertebra or a fragility fracture may be painful, some participants believed osteoporosis was a very painful condition in and of itself. They therefore ascribed pain from many body parts to their osteoporosis. Some participants believed that restriction of physical activities would be beneficial considering their current risk status. There was also a belief that spending too much time thinking about osteoporosis could make the condition worse, and that not much could be done about poor bone health because it is part of the aging process.
In many instances, participants without the disease and those with uncomplicated disease did not see osteoporosis as a serious condition or something that should concern them. This was mainly because it presented with no symptoms or loss of function until one had suffered a complication. Thus, most individuals whose disease was diagnosed at routine screening with no symptoms at that stage did not believe the disease was serious or severe. To some participants, once they were active and could carry out their usual activities, there was no need to worry about the disease. Finally, some participants indicated that osteoporosis is not explicitly life-threatening compared with diseases such as cancer or stroke, reinforcing the belief that osteoporosis is not a serious disease to merit much attention.
Perceived personal risk – Many participants did not see themselves as being at risk of osteoporosis even when they acknowledged that osteoporosis and associated fractures could be of great concern. Even some participants who had a history of fragility fractures attributed the cause to reasons other than weak bones, such as the impact of the fall or medical conditions such as glaucoma or poor vision. Some participants believed that they had strong bones and were unlikely to develop osteoporosis. Others saw osteoporosis as no threat to them because no member of their families had ever been diagnosed with the condition. In some cases, respondents saw their risk status as irrelevant because they felt they had no control over their level of risk or risk factors such as aging.
Concerns about osteoporosis
Some participants expressed concerns and worries about life after being diagnosed with osteoporosis. Three subthemes were identified under concerns studied in 12 included studies: fear of dependence, implications of diagnosis, and medications.
Fear of dependence – Participants who knew about osteoporosis or had vicarious experience of the disease expressed concern about a future of dependence on others due to consequences of severe osteoporosis. They were worried about losing their independence from sustaining multiple fractures, fear of falling, or becoming wheelchair-bound.
Implications of diagnosis – For some participants, being diagnosed with osteoporosis evoked concerns and uncertainties. Participants were concerned about their ability to work and socialize. Emotions associated with the diagnosis included shock, anger, and worry. Some were worried about their self-image, such as loss of height or developing a hump at the back. They felt that diagnosis could heighten awareness of their “at risk” state and increase the feeling of vulnerability. They also felt that the diagnostic test, dual-energy x-ray absorptiometry scan, could provide false-positive results and create anxieties. Others felt that the test could reveal other diseases such as cancer. They were also worried that the test could expose them to radiation. However, declining screening could heighten awareness about the body and evoke fear, especially for those who already had pain. Finally, some participants were worried about being diagnosed because they would become “labeled” with a chronic disease and put in a “sick” category, even when the participants were asymptomatic or did not see osteoporosis as a serious disease.
Medications – Many expressed concern about medications for osteoporosis, including their side effects, costs, efficacy, and having to take too many medications. Concerns were particularly expressed about media reports linking bisphosphonates to esophageal cancer and having to take some medications on an empty stomach. There were also concerns about the uncertainties of long-term effects of the medications because there were inadequate data on that. Finally, there were concerns about having to take medications for an otherwise asymptomatic disease when many patients were already taking several medications for other chronic diseases. Having to take medications served as a reminder that they were sick.
Lack of information from health care providers
This theme was reported in 6 included studies. Participants generally felt that they were not adequately informed about bone health by their health care providers. Some felt that their primary care physicians were not well informed about osteoporosis and they had to find information on their own. Some women felt that male chauvinism was partly to blame for the seemingly inadequate attention paid to the condition because it mainly affects women. Other participants complained that even when they had initiated conversations about their risk with their primary care providers, they were told not to worry about it or that they were not at risk. This contributed to their false sense of not being personally at risk. In one instance, a participant would not accept a relationship between osteoporosis and diet because no health care provider had ever talked about that with her. Table 2 is a summary of the themes with some of their supporting quotations.
Fig 3 summarizes the relationships between the major themes. Information appeared to be unavailable to patients because primary care physicians are not informing them, they do not have access to reliable sources of information, or both. This lack of information leaves patients inadequately informed and breeds misconceptions and unnecessary concerns about the disease. The inadequate information reinforces the misconceptions and heightens patient concerns. Finally, the misconceptions further feed into the concerns.
Ancillary analyses
We observed differences between certain population subgroups. Men generally had a misconception that osteoporosis was a disease of women and perceived their diagnosis as a weakness. They were not open about their diagnosis and would downplay the symptoms, thus presenting after complications had set in. Some men expressed concern that most educational materials had pictures of women, thus reinforcing their notion that osteoporosis is a women’s disease. Some participants diagnosed with osteoporosis did not believe it could be asymptomatic and ascribed many unrelated symptoms to it. In contrast, those not diagnosed with the disease did not see themselves as potentially at risk. Participants aged 55 years or younger did not express much interest in the condition. Participants older than 55 years were concerned about the association between old age and osteoporosis. Table 3 highlights issues brought up by specific population subgroups.
Discussion
We examined qualitative studies that addressed participant knowledge, beliefs, and concerns about bone health. We used a metasynthesis approach to tap into results of many studies that had used qualitative methods to examine participants’ understanding of bone health and its implications. We found that there was widespread awareness but inadequate specific knowledge about osteoporosis. There were many misconceptions and outright false beliefs and concerns among the populations interviewed. We also found that patients at risk of osteoporosis were not receiving adequate information about the condition.
Our finding that inadequate knowledge about osteoporosis is pervasive among studies corroborates the findings of other studies using different methodologies [33–37]. In a review of quantitative surveys on knowledge of osteoporosis, Werner reported serious deficits in knowledge, particularly in the areas of risk factors, consequences of the disease, treatment, and prevention, among various populations, including diagnosed and healthy individuals and even among health care professionals [37]. Although Werner reviewed quantitative studies employing various standardized instruments to assess knowledge, similar findings from our analysis of qualitative studies lend further credence to the observation. A systematic review of quantitative studies of older men’s knowledge about osteoporosis revealed that men had minimal knowledge about the disease process, risk factors, and prevention [33]. Some studies have reported that people who are familiar with the disease either by personal or vicarious experience tend to be more knowledgeable [32, 38]. One study, for example, showed that patients with multiple sclerosis were quite knowledgeable of osteoporosis and its risk factors from interactions with health care providers, although many had not been informed about the association with steroids [39].
Many participants did not see themselves as being at risk of the disease, particularly people older than 55 years who had not been diagnosed. This was found to be partly due to the silent nature of the disease. This was also a common observation in a number of other studies [40–42]. A study in patients with prostate cancer receiving androgen-deprivation therapy, who are at particularly increased risk of osteoporosis, reported a low perceived susceptibility [42]. Our study also showed that many people did not perceive the disease as serious because they did not see it as explicitly life-threatening compared with such diseases as cancer or stroke. Similar findings have been reported in the literature [36, 42, 43]. A study in middle-aged and elderly women showed that although most women (80%) saw osteoporosis as a concern, few (15%) thought it was serious [36]. Younger people did not show concern about the disease probably because it is seen mainly in the elderly.
Patients’ knowledge about a condition can be influenced by a number of factors including education level, ethnicity, language barriers, and socioeconomic status, among others [44]. In addition, our findings of inadequate knowledge, misconceptions, and even concerns about the disease could be attributed in part to lack of information from health care providers. Participants felt that their primary care providers did not adequately apprise them of their osteoporosis risks and educate them on prevention. Similar findings have been reported in other studies [45, 46]. In some studies, patients cite their main source of information on bone health as family and friends, newspapers, television, and the internet [36, 46]. In one such study, physicians ranked fifth as a source of information on osteoporosis [46]. In some instances, patients who found information on their own and raised it with their physicians were told it was not a problem [39]. In contrast, one study showed that physicians were by far the major source of information on bone health, with relatives and electronic media in distant second and third, respectively [47]. Information from mass media or from friends and family may not be reliable and may be a potential source of misinformation, although some credible sites exist on the internet.
Although our study reflected the views of many population groups, including women and men, those with and without osteoporosis, young and old, and participants in various contexts, it had some limitations. Because our study was a qualitative metasynthesis, we analyzed themes and findings from many studies with varied qualitative approaches, contexts, and study quality. Thus our findings may not apply in all contexts. Our systematic search for literature in the databases was up through 2016 and we could have potentially missed some recent studies. However, we did not think further searches would yield any novel findings because we observed a saturation of themes. Finally, as with any systematic review of the literature we are constraint to the data reported in the individual studies. Further analysis to provide detailed information on specific populations such as risk lever (low risk versus moderate risk with known low bone density versus high risk with prevalent osteoporosis fractures), by type of setting (primary versus hospital setting), or minority groups could not be performed.
Conclusion
Although there was general awareness of osteoporosis, many misconceptions and concerns were evident. Education on bone health needs to reinforce areas of knowledge and address deficits, misconceptions, and concerns using a multi-level approach involving both providers and health information consumers. Primary care providers need to be educated on osteoporosis and its ramifications so they can play a leading role in educating patients on prevention, screening, and treatment. Resources for self-education also need to be available to individuals and the general public. Since many people already look to the internet for health information, making credible resources available online could go a long way in addressing the information gaps.
Supporting information
S1 Table [doc]
PRISMA 2009 checklist.
S2 Table [docx]
Medline search strategy.
S3 Table [docx]
Individual quality assessment of included studies.
S1 File [docx]
Excluded studies.
Zdroje
1. Consensus development conference: diagnosis, prophylaxis, and treatment of osteoporosis. 1993 Jun. Report No.: 0002-9343 (Print) 0002-9343 Contract No.: 6.
2. World Health Organization. WHO Scientific Group on the Assessment of Osteoporosis at Primary Health Care Level. Geneva, Switzerland: WHO, 2007.
3. National Osteoporosis Foundation. What is Osteoporosis and What Causes It? 2017 [cited 2018 March 15]. Available from: https://www.nof.org/patients/what-is-osteoporosis.
4. Office of the Surgeon General. Reports of the Surgeon General. Bone Health and Osteoporosis: A Report of the Surgeon General. Rockville (MD): Office of the Surgeon General (US); 2004.
5. Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research. 2007;22(3):465–75. Epub 2006/12/06. doi: 10.1359/jbmr.061113 17144789.
6. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Annals of internal medicine. 2009;151(4):W65–94. Epub 2009/07/23. doi: 10.7326/0003-4819-151-4-200908180-00136 19622512.
7. Lockwood C, Porrit K, Munn Z, Rittenmeyer L, Salmond S, Bjerrum M, et al. Chapter 2: Systematic reviews of qualitative evidence. In: Aromataris E, Munn Z, editors. Joanna Briggs Institute Reviewer's Manual: The Joanna Briggs Institute; 2017.
8. Backett-Milburn K, Parry O, Mauthner N. 'I'll worry about that when it comes along': osteoporosis, a meaningful issue for women at mid-life? Health Educ Res. 2000;15(2):153–62. doi: 10.1093/her/15.2.153 10751374.
9. Baheiraei A, Ritchie JE, Eisman JA, Nguyen TV. Exploring factors influencing osteoporosis prevention and control: a qualitative study of Iranian men and women in Australia. Maturitas. 2006;54(2):127–34. doi: 10.1016/j.maturitas.2005.09.010 16257152.
10. Besser SJ, Anderson JE, Weinman J. How do osteoporosis patients perceive their illness and treatment? Implications for clinical practice. Arch Osteoporos. 2012;7:115–24. doi: 10.1007/s11657-012-0089-9 23225289.
11. Burgener M, Arnold M, Katz JN, Polinski JM, Cabral D, Avorn J, et al. Older adults' knowledge and beliefs about osteoporosis: results of semistructured interviews used for the development of educational materials. J Rheumatol. 2005;32(4):673–7. 15801024.
12. Edwards BJ, Iris M, Ferkel E, Feinglass J. Postmenopausal women with minimal trauma fractures are unapprised of the existence of low bone mass or osteoporosis. Maturitas. 2006;53(3):260–6. doi: 10.1016/j.maturitas.2005.05.008 16039809.
13. Hagy LF, Brochetti D, Duncan SE. Focus groups identified women's perceptions of dairy foods. J Women Aging. 2000;12(3-4):99–115. doi: 10.1300/J074v12n03_07 11151357.
14. Iversen MD, Vora RR, Servi A, Solomon DH. Factors affecting adherence to osteoporosis medications: a focus group approach examining viewpoints of patients and providers. J Geriatr Phys Ther. 2011;34(2):72–81. doi: 10.1097/JPT.0b013e3181ff03b4 21937896; PubMed Central PMCID: PMCNIHMS275883 PMC3181084.
15. Jachna CM, Forbes-Thompson S. Osteoporosis: Health beliefs and barriers to treatment in an assisted living facility. J Gerontol Nurs. 2005;31(1):24–30; quiz 42-3. doi: 10.3928/0098-9134-20050101-09 15675781.
16. Lau E, Papaioannou A, Dolovich L, Adachi J, Sawka AM, Burns S, et al. Patients' adherence to osteoporosis therapy: exploring the perceptions of postmenopausal women. Can Fam Physician. 2008;54(3):394–402. 18337534; PubMed Central PMCID: PMC2278357.
17. Mazor KM, Velten S, Andrade SE, Yood RA. Older women's views about prescription osteoporosis medication: a cross-sectional, qualitative study. Drugs Aging. 2010;27(12):999–1008. doi: 10.2165/11584790-000000000-00000 21087069.
18. Nielsen D, Huniche L, Brixen K, Sahota O, Masud T. Handling knowledge on osteoporosis--a qualitative study. Scand J Caring Sci. 2013;27(3):516–24. doi: 10.1111/j.1471-6712.2012.01055.x 22924528.
19. Nielsen DS, Brixen K, Huniche L. Men's experiences of living with osteoporosis: focus group interviews. Am j. 2011;5(2):166–76. doi: 10.1177/1557988310372800 20798147.
20. Quantock C, Beynon J. Evaluating an osteoporosis service using a focus group. Nurs Stand. 1997;11(42):45–7. doi: 10.7748/ns.11.42.45.s49 9283416.
21. Reventlow S, Bang H. Brittle bones: ageing or threat of disease exploring women's cultural models of osteoporosis. Scand J Public Health. 2006;34(3):320–6. doi: 10.1080/14034940500327869 16754591.
22. Reventlow SD. Perceived risk of osteoporosis: restricted physical activities? Qualitative interview study with women in their sixties. Scand J Prim Health Care. 2007;25(3):160–5. doi: 10.1080/02813430701305668 17846934; PubMed Central PMCID: PMC3379775.
23. Richardson JC, Hassell AB, Hay EM, Thomas E. "I'd rather go and know": women's understanding and experience of DEXA scanning for osteoporosis. Health Expect. 2002;5(2):114–26. doi: 10.1046/j.1369-6513.2002.00173.x 12031052.
24. Roberto KA, Reynolds SG. The meaning of osteoporosis in the lives of rural older women. Health Care for Women International. 2001;22(6):599–611 13p. doi: 10.1080/07399330127198 12141850. Language: English. Entry Date: 20050712. Revision Date: 20150818. Publication Type: Journal Article.
25. Rothmann MJ, Huniche L, Ammentorp J, Barkmann R, Gluer CC, Hermann AP. Women's perspectives and experiences on screening for osteoporosis (Risk-stratified Osteoporosis Strategy Evaluation, ROSE). Arch Osteoporos. 2014;9:192. doi: 10.1007/s11657-014-0192-1 25134980.
26. Sale JE, Beaton DE, Sujic R, Bogoch ER. 'If it was osteoporosis, I would have really hurt myself.' Ambiguity about osteoporosis and osteoporosis care despite a screening programme to educate fragility fracture patients. J Eval Clin Pract. 2010;16(3):590–6. doi: 10.1111/j.1365-2753.2009.01176.x 20102434.
27. Sale JE, Gignac MA, Hawker G, Beaton D, Bogoch E, Webster F, et al. Non-pharmacological strategies used by patients at high risk for future fracture to manage fracture risk--a qualitative study. Osteoporos Int. 2014;25(1):281–8. doi: 10.1007/s00198-013-2405-7 23740423.
28. Skolbekken JA, Osterlie W, Forsmo S. Brittle bones, pain and fractures--lay constructions of osteoporosis among Norwegian women attending the Nord-Trondelag Health Study (HUNT). Soc Sci Med. 2008;66(12):2562–72. doi: 10.1016/j.socscimed.2008.02.022 18384922.
29. Solimeo SL, Weber TJ, Gold DT. Older men's explanatory model for osteoporosis. Gerontologist. 2011;51(4):530–9. doi: 10.1093/geront/gnq123 21310768; PubMed Central PMCID: PMC3146803.
30. Unson CG, Dunbar N, Curry L, Kenyon L, Prestwood K. The effects of knowledge, attitudes, and significant others on decisions to enroll in a clinical trial on osteoporosis: implications for recruitment of older African-American women. J Natl Med Assoc. 2001;93(10):392–401; discussion 2-4. 11688920; PubMed Central PMCID: PMC2594076.
31. Weston JM, Norris EV, Clark EM. The invisible disease: making sense of an osteoporosis diagnosis in older age. Qual Health Res. 2011;21(12):1692–704. doi: 10.1177/1049732311416825 21810994; PubMed Central PMCID: PMC3240909.
32. Hvas L, Reventlow S, Jensen HL, Malterud K. Awareness of risk of osteoporosis may cause uncertainty and worry in menopausal women. Scand J Public Health. 2005;33(3):203–7. doi: 10.1080/14034940510005716 16040461.
33. Gaines JM, Marx KA. Older men's knowledge about osteoporosis and educational interventions to increase osteoporosis knowledge in older men: a systematic review. Maturitas. 2011;68(1):5–12. Epub 2010/10/19. doi: 10.1016/j.maturitas.2010.08.013 20950969.
34. Gaines JM, Marx KA, Caudill J, Parrish S, Landsman J, Narrett M, et al. Older men's knowledge of osteoporosis and the prevalence of risk factors. Journal of clinical densitometry: the official journal of the International Society for Clinical Densitometry. 2010;13(2):204–9. Epub 2010/03/30. doi: 10.1016/j.jocd.2010.01.004 20347370.
35. Giangregorio L, Dolovich L, Cranney A, Adili A, Debeer J, Papaioannou A, et al. Osteoporosis risk perceptions among patients who have sustained a fragility fracture. Patient Educ Couns. 2009;74(2):213–20. doi: 10.1016/j.pec.2008.08.001 18977628.
36. Saw SM, Hong CY, Lee J, Wong ML, Chan MF, Cheng A, et al. Awareness and health beliefs of women towards osteoporosis. Osteoporos Int. 2003;14(7):595–601. doi: 10.1007/s00198-003-1403-6 12830368.
37. Werner P. Knowledge about osteoporosis: assessment, correlates and outcomes. Osteoporos Int. 2005;16(2):115–27. Epub 2004/11/02. doi: 10.1007/s00198-004-1750-y 15517187.
38. Giangregorio L, Thabane L, Cranney A, Adili A, deBeer J, Dolovich L, et al. Osteoporosis knowledge among individuals with recent fragility fracture. Orthopedic nursing. 2010;29(2):99–107. Epub 2010/03/26. doi: 10.1097/NOR.0b013e3181d2436c 20335769; PubMed Central PMCID: PMC5101069.
39. Sharts-Hopko NC, Sullivan MP. Beliefs, perceptions, and practices related to osteoporosis risk reduction among women with multiple sclerosis. Rehabil Nurs. 2002;27(6):232–6. doi: 10.1002/j.2048-7940.2002.tb02020.x 12432671.
40. Meadows LM, Mrkonjic LA, Lagendyk LE, Petersen KM. After the fall: women's views of fractures in relation to bone health at midlife. Women Health. 2004;39(2):47–62. doi: 10.1300/J013v39n02_04 15130861.
41. Gerend MA, Erchull MJ, Aiken LS, Maner JK. Reasons and risk: factors underlying women's perceptions of susceptibility to osteoporosis. Maturitas. 2006;55(3):227–37. doi: 10.1016/j.maturitas.2006.03.003 16650699.
42. Nadler M, Alibhai S, Catton P, Catton C, To MJ, Jones JM. Osteoporosis knowledge, health beliefs, and healthy bone behaviours in patients on androgen-deprivation therapy (ADT) for prostate cancer. BJU international. 2013;111(8):1301–9. Epub 2013/01/29. doi: 10.1111/j.1464-410X.2012.11777.x 23351062.
43. Siris ES, Gehlbach S, Adachi JD, Boonen S, Chapurlat RD, Compston JE, et al. Failure to perceive increased risk of fracture in women 55 years and older: the Global Longitudinal Study of Osteoporosis in Women (GLOW). Osteoporos Int. 2011;22(1):27–35. Epub 2010/04/02. doi: 10.1007/s00198-010-1211-8 PubMed Central PMCID: PMC3017306. 20358360
44. Wright NC, Melton ME, Sohail M, Herbey I, Davies S, Levitan EB, et al. Race Plays a Role in the Knowledge, Attitudes, and Beliefs of Women with Osteoporosis. J Racial Ethn Health Disparities. 2019. Epub 2019/02/13. doi: 10.1007/s40615-019-00569-w 30747331.
45. Meadows LM, Mrkonjic LA. Breaking -- bad news: women's experiences of fractures at midlife. Canadian Journal of Public Health. 2003;94(6):427–30 4p. 14700241. Language: English. Entry Date: 20040813. Revision Date: 20150711. Publication Type: Journal Article.
46. Juby AG, Davis P. A prospective evaluation of the awareness, knowledge, risk factors and current treatment of osteoporosis in a cohort of elderly subjects. Osteoporos Int. 2001;12(8):617–22. Epub 2001/10/03. doi: 10.1007/s001980170060 11580074.
47. Kutsal YG, Atalay A, Arslan S, Basaran A, Canturk F, Cindas A, et al. Awareness of osteoporotic patients. Osteoporos Int. 2005;16(2):128–33. doi: 10.1007/s00198-004-1678-2 15197545.
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