Arterial blood gas analysis in dogs with bronchomalacia
Autoři:
Yohei Hara aff001; Kenji Teshima aff001; Yoshiki Yamaya aff001
Působiště autorů:
Veterinary Anesthesiology & Respiratory Research Laboratory, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa Japan
aff001
Vyšlo v časopise:
PLoS ONE 14(12)
Kategorie:
Research Article
doi:
https://doi.org/10.1371/journal.pone.0227194
Souhrn
Canine bronchomalacia (CBM) is a structural airway disease leading to chronic cough and intermittent respiratory distress, primarily affecting elderly dogs of small breeds. Results of blood gas analysis have been reported in dogs with several diseases, but not yet in those with CBM. Eleven dogs with CBM were recruited in this study. Most dogs presented with mild hypoxemia and normocapnia, and all with increased alveolar-arterial difference for O2 (A-aDO2). In computed tomography, abnormal lung patterns, such as atelectasis and parenchymal band, were detected in all dogs, consistent with the regions affected by CBM. We conclude that CBM causes abnormal lung patterns and results in impaired oxygenation. Blood gas analysis is a useful tool for detecting mild pulmonary lesions and concurrent CBM.
Klíčová slova:
Blood – Bronchi – Computed axial tomography – Dogs – Gas analysis – Respiratory physiology – Veterinary diagnostics – Veterinary medicine
Zdroje
1. Tan JZ, Ditchfield M, Freezer N. Tracheobronchomalacia in children: review of diagnosis and definition. Pediatr Radiol. 2012;42: 906–915. doi: 10.1007/s00247-012-2367-5 22426568
2. Heidinger BH, Occhipinti M, Eisenberg RL, Bankier AA. Imaging of large airways disorders. AJR Am J Roentgenol. 2015;205: 41–56. doi: 10.2214/AJR.14.13857 26102379
3. Pan W, Peng D, Luo J, Liu E, Luo Z, Dai J, et al. Clinical features of airway malacia in children: a retrospective analysis of 459 patients. Int J Clin Exp Med. 2014;7: 3005–3012. 25356175
4. Buitrago DH, Wilson JL, Parikh M, Majid A, Gangadharan SP. Current concepts in severe adult tracheobronchomalacia: evaluation and treatment. J Thorac Dis. 2017;9: E57–E66. doi: 10.21037/jtd.2017.01.13 28203438
5. Johnson LR, Pollard RE. Tracheal collapse and bronchomalacia in dogs: 58 cases (7 /2001-1 /2008). J Vet Intern Med. 2010;24: 298–305. doi: 10.1111/j.1939-1676.2009.0451.x 20051001
6. Bottero E, Bellino C, De Lorenzi D, Ruggiero P, Tarducci A, D’Angelo A, et al. Clinical evaluation and endoscopic classification of bronchomalacia in dogs. J Vet Intern Med. 2013;27: 840–846 doi: 10.1111/jvim.12096 23647392
7. Adamama-Moraitou KK, Pardali D, Day MJ, Prassinos NN, Kritsepi-Konstantinou M, Patsikas MN, et al. Canine bronchomalacia: a clinicopathological study of 18 cases diagnosed by endoscopy. Vet J. 2012;191: 261–266. doi: 10.1016/j.tvjl.2010.11.021 21177126
8. Puighibet Z, Costa-Farré C, Santos L, Canfrán S, Gómez de Segura IA. The sedative effects of intramuscular low-dose medetomidine in combination with butorphanol or methadone in dogs. Vet Anaesth Analg. 2015;42: 590–596. doi: 10.1111/vaa.12256 25800204
9. Wagner PD. The physiological basis of pulmonary gas exchange: implications for clinical interpretation of arterial blood gases. Eur Respir J. 2015;45: 227–243. doi: 10.1183/09031936.00039214 25323225
10. Viitanen SJ, Laurila HP, Lilja-Maula LI, Melamies MA, Rantala M, Rajamäki MM. Serum C-reactive protein as a diagnostic biomarker in dogs with bacterial respiratory diseases. J Vet Intern Med. 2014;28: 84–91 doi: 10.1111/jvim.12262 24351049
11. Hoareau GL, Jourdan G, Mellema M, Verwaerde P. Evaluation of arterial blood gases and arterial blood pressures in brachycephalic dogs. J Vet Intern Med. 2012;26: 897–904 doi: 10.1111/j.1939-1676.2012.00941.x 22574946
12. Stadler K, Hartman S, Matheson J, O'Brien R. Computed tomographic imaging of dogs with primary laryngeal or tracheal airway obstruction. Vet Radiol Ultrasound. 2011;52: 377–384. doi: 10.1111/j.1740-8261.2011.01816.x 21447037
13. De Lorenzi D, Bertoncello D, Drigo M. Bronchial abnormalities found in a consecutive series of 40 brachycephalic dogs. J Am Vet Med Assoc. 2009;235: 835–840. doi: 10.2460/javma.235.7.835 19793013
14. Roels E, Couvreur T, Farnir F, Clercx C, Verschakelen J, Bolen G. Comparison between sedation and general anesthesia for high resolution computed tomographic characterization of canine idiopathic pulmonary fibrosis in West Highland white terriers. Vet Radiol Ultrasound. 2017;58: 284–294. doi: 10.1111/vru.12481 28229501
15. Scrivani PV, Thompson MS, Dykes NL, Holmes NL, Southard TL, Gerdin JA, et al. Relationships among subgross anatomy, computed tomography, and histologic findings in dogs with disease localized to the pulmonary acini. Vet Radiol Ultrasound. 2012;53: 1–10. doi: 10.1111/j.1740-8261.2011.01881.x 22092550
16. Bach JF, Rozanski EA, Bedenice D, Chan DL, Freeman LM, Lofgren JL, et al. Association of expiratory airway dysfunction with marked obesity in healthy adult dogs. Am J Vet Res. 2007;68: 670–675. doi: 10.2460/ajvr.68.6.670 17542702
17. Burden RJ, Shann F, Butt W, Ditchfield M. Tracheobronchial malacia and stenosis in children in intensive care: bronchograms help to predict outcome. Thorax. 1999;54: 511–517. doi: 10.1136/thx.54.6.511 10335005
18. Ullmann N, Secinaro A, Menchini L, Caggiano S, Verrillo E, Santangelo TP, et al. Dynamic expiratory CT: An effective non-invasive diagnostic exam for fragile children with suspected tracheo-bronchomalacia. Pediatr Pulmonol. 2018;53: 73–80. doi: 10.1002/ppul.23831 29148213
19. Macready DM, Johnson LR, Pollard RE. Fluoroscopic and radiographic evaluation of tracheal collapse in dogs: 62 cases (2001–2006). J Am Vet Med Assoc. 2007;230: 1870–1876. doi: 10.2460/javma.230.12.1870 17571993
20. Kim H, Kim YJ, Lee H, An T, Yu J, Yoon H, et al. Computed tomographic and radiographic bronchial collapse may be a normal characteristic of forced expiration in dogs. Vet Radiol Ultrasound. 2018;59: 551–563. doi: 10.1111/vru.12625 29786925
21. Oh D, Lee S, Kim S, Choen S, Choi M, Yoon J. Computed tomographic bronchial collapsibility values over 50% may be detected in healthy dogs. Vet Radiol Ultrasound. 2019;60: 28–37. doi: 10.1111/vru.12692 30311323
22. Meler E, Pressler BM, Heng HG, Baird DK. Diffuse cylindrical bronchiectasis due to eosinophilic bronchopneumopathy in a dog. Can Vet J. 2010;51: 753–756. 20885829
23. Corcoran BM, King LG, Schwarz T, Hammond G, Sullivan M. Further characterisation of the clinical features of chronic pulmonary disease in West Highland white terriers. Vet Rec. 2011;168: 355.
24. Sarkar M, Niranjan N, Banyal PK. Mechanisms of hypoxemia. Lung India. 2017; 34: 47–60. doi: 10.4103/0970-2113.197116 28144061
25. Sorbini CA, Grassi V, Solinas E, Muiesan G. Arterial oxygen tension in relation to age in healthy subjects. Respiration. 1968;25: 3–13. doi: 10.1159/000192549 5644025
26. Aguilera-Tejero E, Fernández H, Estepa JC, Mayer-Valor R, Rodríguez M. Arterial blood gases and acid-base balance in geriatric dogs. Res Vet Sci. 1997;63: 253–256. doi: 10.1016/s0034-5288(97)90029-1 9491452
27. Hansell DM, Bankier AA, MacMahon H, McLoud TC, Müller NL, Remy J. Fleischner Society: Glossary of Terms for Thoracic Imaging. Radiology. 2008;246: 697–722. doi: 10.1148/radiol.2462070712 18195376
28. Thierry F, Handel I, Hammond G, King LG, Corcoran BM, Schwarz T. Further characterization of computed tomographic and clinical features for staging and prognosis of idiopathic pulmonary fibrosis in West Highland white terriers. Vet Radiol Ultrasound. 2017;58: 381–388. doi: 10.1111/vru.12491 28335088
29. Kligerman SJ, Henry T, Lin CT, Franks TJ, Galvin JR. Mosaic attenuation: etiology, methods of differentiation, and pitfalls. Radiographics. 2015;35: 1360–1380. doi: 10.1148/rg.2015140308 26274445
Článek vyšel v časopise
PLOS One
2019 Číslo 12
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