#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

EN

Correction: Leveraging correlations between variants in polygenic risk scores to detect heterogeneity in GWAS cohorts

English version

Autoři: Jie Yuan; Hengrui Xing; Alexandre Louis Lamy; ; Todd Lencz; Itsik Pe’er
Vyšlo v časopise: Correction: Leveraging correlations between variants in polygenic risk scores to detect heterogeneity in GWAS cohorts. PLoS Genet 16(10): e32767. doi:10.1371/journal.pgen.1009158
Kategorie: Correction
doi: https://doi.org/10.1371/journal.pgen.1009158

Zdroje

1. Yuan J, Xing H, Lamy AL, The Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lencz T, Pe’er I (2020) Leveraging correlations between variants in polygenic risk scores to detect heterogeneity in GWAS cohorts. PLoS Genet 16(9): e1009015. https://doi.org/10.1371/journal.pgen.1009015 32956347

Článek Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots

Článek A single Ho-induced double-strand break at the MAT locus is lethal in Candida glabrata

Článek A Rad51-independent pathway promotes single-strand template repair in gene editing

Článek Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

Článek C. elegans CLASP/CLS-2 negatively regulates membrane ingression throughout the oocyte cortex and is required for polar body extrusion

Článek The O-GlcNAc transferase OGT is a conserved and essential regulator of the cellular and organismal response to hypertonic stress

Článek Chromosome separation during Drosophila male meiosis I requires separase-mediated cleavage of the homolog conjunction protein UNO

Článek How noncrossover homologs are conjoined and segregated in Drosophila male meiosis I: Stable but reversible homolog linkers require a novel Separase target protein

Článek Human ABCB1 with an ABCB11-like degenerate nucleotide binding site maintains transport activity by avoiding nucleotide occlusion

Článek Dbp5 associates with RNA-bound Mex67 and Nab2 and its localization at the nuclear pore complex is sufficient for mRNP export and cell viability

Článek RNA-directed DNA Methylation

Článek The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations

Článek A cautionary note on the use of unsupervised machine learning algorithms to characterise malaria parasite population structure from genetic distance matrices

Článek Selection and hybridization shaped the rapid spread of African honey bee ancestry in the Americas

Článek Selection for ancient periodic motifs that do not impart DNA bending

Článek The Ccr4-Not complex regulates TORC1 signaling and mitochondrial metabolism by promoting vacuole V-ATPase activity

Článek Mutation of NEKL-4/NEK10 and TTLL genes suppress neuronal ciliary degeneration caused by loss of CCPP-1 deglutamylase function

Článek Phenotype-genotype comorbidity analysis of patients with rare disorders provides insight into their pathological and molecular bases

Článek Cells with loss-of-heterozygosity after exposure to ionizing radiation in Drosophila are culled by p53-dependent and p53-independent mechanisms

Článek Identification of the transcription factor Miz1 as an essential regulator of diphthamide biosynthesis using a CRISPR-mediated genome-wide screen

Článek Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function

Článek PE homeostasis rebalanced through mitochondria-ER lipid exchange prevents retinal degeneration in Drosophila

Článek Chromosome number evolves at equal rates in holocentric and monocentric clades

Článek Metabolism of long-chain fatty acids affects disulfide bond formation in Escherichia coli and activates envelope stress response pathways as a combat strategy

Článek Disentangling the determinants of transposable elements dynamics in vertebrate genomes using empirical evidences and simulations

Článek Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing

Článek Automated feature extraction from population wearable device data identified novel loci associated with sleep and circadian rhythms

Článek Diversified regulation of circadian clock gene expression following whole genome duplication

Článek A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling

Článek Inactivation of the mitochondrial protease Afg3l2 results in severely diminished respiratory chain activity and widespread defects in mitochondrial gene expression

Článek Effect of H2A.Z deletion is rescued by compensatory mutations in Fusarium graminearum

Článek Correction: Integrating transcriptomic network reconstruction and eQTL analyses reveals mechanistic connections between genomic architecture and Brassica rapa development

Článek Correction: Ferritin heavy chain protects the developing wing from reactive oxygen species and ferroptosis

Článek Correction: Molecular predictors of brain metastasis-related microRNAs in lung adenocarcinoma

Článek Drosophila Caliban preserves intestinal homeostasis and lifespan through regulating mitochondrial dynamics and redox state in enterocytes

Článek Correction: A kinesin Klp10A mediates cell cycle-dependent shuttling of Piwi between nucleus and nuage

Článek Correction: Architecture of the Escherichia coli nucleoid

Článek Correction: The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes

Článek Dual function of perivascular fibroblasts in vascular stabilization in zebrafish

Článek Drosophila phosphatidylinositol-4 kinase fwd promotes mitochondrial fission and can suppress Pink1/parkin phenotypes

Článek A new domestic cat genome assembly based on long sequence reads empowers feline genomic medicine and identifies a novel gene for dwarfism

Článek Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease

Článek Transcriptome and epigenome diversity and plasticity of muscle stem cells following transplantation

Článek Extensive trimming of short single-stranded DNA oligonucleotides during replication-coupled gene editing in mammalian cells

Článek The ninth life of the cat reference genome, Felis_catus

Článek Insulin signaling represents a gating mechanism between different memory phases in Drosophila larvae

Článek Major role of iron uptake systems in the intrinsic extra-intestinal virulence of the genus Escherichia revealed by a genome-wide association study

Článek Genetically predicted telomere length is associated with clonal somatic copy number alterations in peripheral leukocytes

Článek DNA supercoiling differences in bacteria result from disparate DNA gyrase activation by polyamines

Článek Exploring the Complexity of Protein-Level Dosage Compensation that Fine-Tunes Stoichiometry of Multiprotein Complexes

Článek Loss of the RNA trimethylguanosine cap is compatible with nuclear accumulation of spliceosomal snRNAs but not pre-mRNA splicing or snRNA processing during animal development

Článek Evaluation of both exonic and intronic variants for effects on RNA splicing allows for accurate assessment of the effectiveness of precision therapies

Článek Tissue-specific isoforms of the single C. elegans Ryanodine receptor gene unc-68 control specific functions

Článek CenH3 distribution reveals extended centromeres in the model beetle Tribolium castaneum

Článek A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank

Článek Correction: Telomere length-dependent transcription and epigenetic modifications in promoters remote from telomere ends

Článek Evolution of linkage and genome expansion in protocells: The origin of chromosomes

Článek Correction: yippee like 3 (ypel3) is a novel gene required for myelinating and perineurial glia development

Článek Auxin apical dominance governed by the OsAsp1-OsTIF1 complex determines distinctive rice caryopses development on different branches

Článek Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for “polygenic epistasis”

Článek DOT-1.1-dependent H3K79 methylation promotes normal meiotic progression and meiotic checkpoint function in C. elegans

Článek Developmental constraint shaped genome evolution and erythrocyte loss in Antarctic fishes following paleoclimate change

Článek AKH-FOXO pathway regulates starvation-induced sleep loss through remodeling of the small ventral lateral neuron dorsal projections

Článek Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling

Článek vyšel v časopise

PLOS Genetics

2020 Číslo 10

Nejčtenější tento týden

Nejčtenější v tomto čísle

Kurzy

Zvyšte si kvalifikaci online z pohodlí domova

plice

INSIGHTS from European Respiratory Congress

nový kurz

Současné pohledy na riziko v parodontologii

Autoři: MUDr. Ladislav Korábek, CSc., MBA

Svět praktické medicíny 3/2024 (znalostní test z časopisu)

Kardiologické projevy hypereozinofilií

Autoři: prof. MUDr. Petr Němec, Ph.D.

Střevní příprava před kolonoskopií

Autoři: MUDr. Klára Kmochová, Ph.D.

Kurzy

Podcasty

Doporučená témata

Časopisy

#ADS_BOTTOM_SCRIPTS#