Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

Autoři: Suzanne Vogelezang ^aff001;  Jonathan P. Bradfield ^aff004;  Tarunveer S. Ahluwalia ^aff006;  John A. Curtin ^aff009;  Timo A. Lakka ^aff010;  Niels Grarup ^aff008;  Markus Scholz ^aff013;  Peter J. van der Most ^aff015;  Claire Monnereau ^aff001;  Evie Stergiakouli ^aff016;  Anni Heiskala ^aff019;  Momoko Horikoshi ^aff020;  Iryna O. Fedko ^aff023;  Natalia Vilor-Tejedor ^aff024;  Diana L. Cousminer ^aff028;  Marie Standl ^aff030;  Carol A. Wang ^aff031;  Jorma Viikari ^aff032;  Frank Geller ^aff034;  Carmen Iñiguez ^aff027;  Niina Pitkänen ^aff037;  Alessandra Chesi ^aff028;  Jonas Bacelis ^aff039;  Loic Yengo ^aff041;  Maties Torrent ^aff043;  Ioanna Ntalla ^aff045;  Øyvind Helgeland ^aff046;  Saskia Selzam ^aff048;  Judith M. Vonk ^aff049;  Mohammed H. Zafarmand ^aff050;  Barbara Heude ^aff053;  Ismaa Sadaf Farooqi ^aff054;  Akram Alyass ^aff055;  Robin N. Beaumont ^aff056;  Christian T. Have ^aff008;  Peter Rzehak ^aff057;  Jose Ramon Bilbao ^aff058;  Theresia M. Schnurr ^aff008;  Inês Barroso ^aff061;  Klaus Bønnelykke ^aff006;  Lawrence J. Beilin ^aff063;  Lisbeth Carstensen ^aff034;  Marie-Aline Charles ^aff053;  Bo Chawes ^aff006;  Karine Clément ^aff064;  Ricardo Closa-Monasterolo ^aff065;  Adnan Custovic ^aff066;  Johan G. Eriksson ^aff067;  Joaquin Escribano ^aff065;  Maria Groen-Blokhuis ^aff023;  Veit Grote ^aff057;  Dariusz Gruszfeld ^aff069;  Hakon Hakonarson ^aff005;  Torben Hansen ^aff008;  Andrew T. Hattersley ^aff056;  Mette Hollensted ^aff008;  Jouke-Jan Hottenga ^aff023;  Elina Hyppönen ^aff073;  Stefan Johansson ^aff046;  Raimo Joro ^aff010;  Mika Kähönen ^aff077;  Ville Karhunen ^aff079;  Wieland Kiess ^aff081;  Bridget A. Knight ^aff071;  Berthold Koletzko ^aff057;  Andreas Kühnapfel ^aff013;  Kathrin Landgraf ^aff081;  Jean-Paul Langhendries ^aff083;  Terho Lehtimäki ^aff084;  Jaakko T. Leinonen ^aff086;  Aihuali Li ^aff055;  Virpi Lindi ^aff087;  Estelle Lowry ^aff019;  Mariona Bustamante ^aff024;  Carolina Medina-Gomez ^aff001;  Mads Melbye ^aff034;  Kim F. Michaelsen ^aff092;  Camilla S. Morgen ^aff093;  Trevor A. Mori ^aff063;  Tenna R. H. Nielsen ^aff095;  Harri Niinikoski ^aff097;  Albertine J. Oldehinkel ^aff099;  Katja Pahkala ^aff037;  Kalliope Panoutsopoulou ^aff101;  Oluf Pedersen ^aff008;  Craig E. Pennell ^aff031;  Christine Power ^aff102;  Sijmen A. Reijneveld ^aff103;  Fernando Rivadeneira ^aff003;  Angela Simpson ^aff009;  Peter D. Sly ^aff104;  Jakob Stokholm ^aff006;  Kook K. Teo ^aff106;  Elisabeth Thiering ^aff030;  Nicholas J. Timpson ^aff016;  André G. Uitterlinden ^aff003;  Catharina E. M. van Beijsterveldt ^aff023;  Barbera D. C. van Schaik ^aff108;  Marc Vaudel ^aff046;  Elvira Verduci ^aff109;  Rebecca K. Vinding ^aff006;  Mandy Vogel ^aff081;  Eleftheria Zeggini ^aff101;  Sylvain Sebert ^aff019;  Mads V. Lind ^aff092;  Christopher D. Brown ^aff113;  Loreto Santa-Marina ^aff114;  Eva Reischl ^aff117;  Christine Frithioff-Bøjsøe ^aff008;  David Meyre ^aff055;  Eleanor Wheeler ^aff061;  Ken Ong ^aff119;  Ellen A. Nohr ^aff120;  Tanja G. M. Vrijkotte ^aff050;  Gerard H. Koppelman ^aff121;  Robert Plomin ^aff048;  Pål R. Njølstad ^aff046;  George D. Dedoussis ^aff124;  Philippe Froguel ^aff041;  Thorkild I. A. Sørensen ^aff008;  Bo Jacobsson ^aff039;  Rachel M. Freathy ^aff056;  Babette S. Zemel ^aff070;  Olli Raitakari ^aff037;  Martine Vrijheid ^aff024;  Bjarke Feenstra ^aff034;  Leo-Pekka Lyytikainen ^aff084;  Harold Snieder ^aff015;  Holger Kirsten ^aff013;  Patrick G. Holt ^aff129;  Joachim Heinrich ^aff030;  Elisabeth Widén ^aff086;  Jordi Sunyer ^aff024;  Dorret I. Boomsma ^aff023;  Marjo-Riitta Jarvelin ^aff019;  Antje Körner ^aff081;  George Davey Smith ^aff016;  Jens-Christian Holm ^aff008;  Mustafa Atalay ^aff010;  Clare Murray ^aff009;  Hans Bisgaard ^aff006;  Mark I. McCarthy ^aff020;  ;  Vincent W. V. Jaddoe ^aff001;  Struan F. A. Grant ^aff005;  Janine F. Felix ^aff001;  John A. Curtin ^aff010;  Timo A. Lakka ^aff011;  Markus Scholz ^aff014;  Peter J. van der Most ^aff016;  Evie Stergiakouli ^aff017;  Anni Heiskala ^aff020;  Momoko Horikoshi ^aff021;  Iryna O. Fedko ^aff024;  Natalia Vilor-Tejedor ^aff025;  Diana L. Cousminer ^aff029;  Marie Standl ^aff031;  Carol A. Wang ^aff032;  Jorma Viikari ^aff033;  Frank Geller ^aff035;  Carmen Iñiguez ^aff028;  Niina Pitkänen ^aff038;  Alessandra Chesi ^aff029;  Jonas Bacelis ^aff040;  Loic Yengo ^aff042;  Maties Torrent ^aff044;  Ioanna Ntalla ^aff046;  Øyvind Helgeland ^aff047;  Saskia Selzam ^aff049;  Judith M. Vonk ^aff050;  Mohammed H. Zafarmand ^aff051;  Barbara Heude ^aff054;  Ismaa Sadaf Farooqi ^aff055;  Akram Alyass ^aff056;  Robin N. Beaumont ^aff057;  Peter Rzehak ^aff058;  Jose Ramon Bilbao ^aff059;  Inês Barroso ^aff062;  Lawrence J. Beilin ^aff064;  Lisbeth Carstensen ^aff035;  Marie-Aline Charles ^aff054;  Karine Clément ^aff065;  Ricardo Closa-Monasterolo ^aff066;  Adnan Custovic ^aff067;  Johan G. Eriksson ^aff068;  Joaquin Escribano ^aff066;  Maria Groen-Blokhuis ^aff024;  Veit Grote ^aff058;  Dariusz Gruszfeld ^aff070;  Andrew T. Hattersley ^aff057;  Jouke-Jan Hottenga ^aff024;  Elina Hyppönen ^aff074;  Stefan Johansson ^aff047;  Raimo Joro ^aff011;  Mika Kähönen ^aff078;  Ville Karhunen ^aff080;  Wieland Kiess ^aff082;  Bridget A. Knight ^aff072;  Berthold Koletzko ^aff058;  Andreas Kühnapfel ^aff014;  Kathrin Landgraf ^aff082;  Jean-Paul Langhendries ^aff084;  Terho Lehtimäki ^aff085;  Jaakko T. Leinonen ^aff087;  Aihuali Li ^aff056;  Virpi Lindi ^aff088;  Estelle Lowry ^aff020;  Mariona Bustamante ^aff025;  Mads Melbye ^aff035;  Kim F. Michaelsen ^aff093;  Camilla S. Morgen ^aff094;  Trevor A. Mori ^aff064;  Tenna R. H. Nielsen ^aff096;  Harri Niinikoski ^aff098;  Albertine J. Oldehinkel ^aff100;  Katja Pahkala ^aff038;  Kalliope Panoutsopoulou ^aff102;  Craig E. Pennell ^aff032;  Christine Power ^aff103;  Sijmen A. Reijneveld ^aff104;  Angela Simpson ^aff010;  Peter D. Sly ^aff105;  Kook K. Teo ^aff107;  Elisabeth Thiering ^aff031;  Nicholas J. Timpson ^aff017;  Catharina E. M. van Beijsterveldt ^aff024;  Barbera D. C. van Schaik ^aff109;  Marc Vaudel ^aff047;  Elvira Verduci ^aff110;  Mandy Vogel ^aff082;  Eleftheria Zeggini ^aff102;  Sylvain Sebert ^aff020;  Mads V. Lind ^aff093;  Christopher D. Brown ^aff114;  Loreto Santa-Marina ^aff115;  Eva Reischl ^aff118;  David Meyre ^aff056;  Eleanor Wheeler ^aff062;  Ken Ong ^aff120;  Ellen A. Nohr ^aff121;  Tanja G. M. Vrijkotte ^aff051;  Gerard H. Koppelman ^aff122;  Robert Plomin ^aff049;  Pål R. Njølstad ^aff047;  George D. Dedoussis ^aff125;  Philippe Froguel ^aff042;  Bo Jacobsson ^aff040;  Rachel M. Freathy ^aff057;  Babette S. Zemel ^aff071;  Olli Raitakari ^aff038;  Martine Vrijheid ^aff025;  Bjarke Feenstra ^aff035;  Leo-Pekka Lyytikainen ^aff085;  Harold Snieder ^aff016;  Holger Kirsten ^aff014;  Patrick G. Holt ^aff130;  Joachim Heinrich ^aff031;  Elisabeth Widén ^aff087;  Jordi Sunyer ^aff025;  Dorret I. Boomsma ^aff024;  Marjo-Riitta Jarvelin ^aff020;  Antje Körner ^aff082;  George Davey Smith ^aff017;  Mustafa Atalay ^aff011;  Clare Murray ^aff010;  Mark I. McCarthy ^aff021
Působiště autorů: The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, the Netherlands ^aff001;  Department of Pediatrics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands ^aff002;  Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands ^aff003;  Quantinuum Research LLC, San Diego, California, United States of America ^aff004;  Center for Applied Genomics, Division of Human Genetics, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America ^aff005;  Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark ^aff006;  Steno Diabetes Center Copenhagen, Gentofte, Denmark ^aff007;  Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark ^aff008;  The Bioinformatics Center, Department of Biology, University of Copenhagen, Copenhagen, Denmark ^aff009;  Division of Infection Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, United Kingdom ^aff009;  Division of Infection Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, United Kingdom ^aff010;  Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland ^aff010;  Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland ^aff011;  Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland ^aff011;  Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland ^aff012;  Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland ^aff012;  Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany ^aff013;  Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland ^aff013;  Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany ^aff014;  LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany ^aff014;  LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany ^aff015;  Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands ^aff015;  Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands ^aff016;  MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom ^aff016;  MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom ^aff017;  Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom ^aff017;  Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom ^aff018;  School of Oral and Dental Sciences, University of Bristol, Bristol, United Kingdom ^aff018;  School of Oral and Dental Sciences, University of Bristol, Bristol, United Kingdom ^aff019;  Center for Life Course Health Research, University of Oulu, Oulu, Finland ^aff019;  Center for Life Course Health Research, University of Oulu, Oulu, Finland ^aff020;  Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom ^aff020;  Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom ^aff021;  Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom ^aff021;  Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom ^aff022;  RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan ^aff022;  RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan ^aff023;  Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands ^aff023;  Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands ^aff024;  ISGlobal, Barcelona, Spain ^aff024;  ISGlobal, Barcelona, Spain ^aff025;  Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain ^aff025;  Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain ^aff026;  BarcelonaBeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain ^aff026;  BarcelonaBeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain ^aff027;  CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain ^aff027;  CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain ^aff028;  Division of Human Genetics, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America ^aff028;  Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America ^aff029;  Division of Human Genetics, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America ^aff029;  Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America ^aff030;  Institute of Epidemiology, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany ^aff030;  Institute of Epidemiology, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany ^aff031;  School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle, Newcastle, Australia ^aff031;  School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle, Newcastle, Australia ^aff032;  Department of Medicine, University of Turku, Turku, Finland ^aff032;  Department of Medicine, University of Turku, Turku, Finland ^aff033;  Division of Medicine, Turku University Hospital, Turku, Finland ^aff033;  Division of Medicine, Turku University Hospital, Turku, Finland ^aff034;  Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark ^aff034;  Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark ^aff035;  Department of Statistics and Computational Research–Universitat de València, València, Spain ^aff035;  Department of Statistics and Computational Research–Universitat de València, València, Spain ^aff036;  Epidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, València, Spain ^aff036;  Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland ^aff037;  Epidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, València, Spain ^aff037;  Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland ^aff038;  Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland ^aff038;  Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland ^aff039;  Department of Obstetrics and Gynecology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg Sweden ^aff039;  Department of Obstetrics and Gynecology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg Sweden ^aff040;  Region Västra Götaland, Sahlgrenska University Hospital, Department of Obstetrics and Gynecology, Gothenburg Sweden ^aff040;  Region Västra Götaland, Sahlgrenska University Hospital, Department of Obstetrics and Gynecology, Gothenburg Sweden ^aff041;  University Lille, Centre National de la Recherche Scientifique, Institut Pasteur de Lille, UMR 8199—European Genomic Institute for Diabetes, Lille, France ^aff041;  University Lille, Centre National de la Recherche Scientifique, Institut Pasteur de Lille, UMR 8199—European Genomic Institute for Diabetes, Lille, France ^aff042;  Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia ^aff042;  Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia ^aff043;  Area de Salut de Menorca ib-salut, Menorca, Spain ^aff043;  Area de Salut de Menorca ib-salut, Menorca, Spain ^aff044;  Institut d'Investigacio Sanitaria Illes Balears (IdISBa), Palma de Mallorca, Spain ^aff044;  Institut d'Investigacio Sanitaria Illes Balears (IdISBa), Palma de Mallorca, Spain ^aff045;  William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom ^aff045;  KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway ^aff046;  William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom ^aff046;  KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway ^aff047;  Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway ^aff047;  Department of Genetics and Bioinformatics, Health Data and Digitalization, Norwegian Institute of Public Health, Oslo, Norway ^aff048;  Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom ^aff048;  Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United Kingdom ^aff049;  Department of Epidemiology, GRIAC (Groningen Research Institute for Asthma and COPD), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands ^aff049;  Department of Epidemiology, GRIAC (Groningen Research Institute for Asthma and COPD), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands ^aff050;  Department of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands ^aff050;  Department of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands ^aff051;  Department of Obstetrics & Gynecology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands ^aff051;  Department of Obstetrics & Gynecology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands ^aff052;  Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands ^aff052;  Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands ^aff053;  Université de Paris, CRESS, INSERM, INRA, Paris, France ^aff053;  Université de Paris, CRESS, INSERM, INRA, Paris, France ^aff054;  University of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, United Kingdom ^aff054;  University of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, United Kingdom ^aff055;  Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada ^aff055;  Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada ^aff056;  Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Exeter, United Kingdom ^aff056;  Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Exeter, United Kingdom ^aff057;  Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, Ludwig-Maximilians Universität München (LMU), Munich, Germany ^aff057;  Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, Ludwig-Maximilians Universität München (LMU), Munich, Germany ^aff058;  University of the Basque Country (UPV/EHU), Leioa, Spain ^aff058;  University of the Basque Country (UPV/EHU), Leioa, Spain ^aff059;  Biocrues-Bizkaia Health Research Institute, Barakaldo, Spain ^aff059;  Biocrues-Bizkaia Health Research Institute, Barakaldo, Spain ^aff060;  CIBER Diabetes y Enfermedades Metabólicas (CIBERDEM), Spain ^aff060;  CIBER Diabetes y Enfermedades Metabólicas (CIBERDEM), Spain ^aff061;  Wellcome Sanger Institute, Cambridge, United Kingdom ^aff061;  MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom ^aff062;  Wellcome Sanger Institute, Cambridge, United Kingdom ^aff062;  MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom ^aff063;  Medical School, The University of Western Australia, Perth, Western Australia, Australia ^aff063;  Medical School, The University of Western Australia, Perth, Western Australia, Australia ^aff064;  Nutrition and Obesities; systemic approaches research unit, Sorbonne University, INSERM, Pitie- Salpêtrière Hospital, Assistance Publique hôpital de Paris, Paris, France ^aff064;  Nutrition and Obesities; systemic approaches research unit, Sorbonne University, INSERM, Pitie- Salpêtrière Hospital, Assistance Publique hôpital de Paris, Paris, France ^aff065;  Pediatrics, Nutrition and Development Research Unit, Universitat Rovira i Virgili, IISPV, Reus, Spain ^aff065;  Pediatrics, Nutrition and Development Research Unit, Universitat Rovira i Virgili, IISPV, Reus, Spain ^aff066;  National Heart and Lung Institute, Imperial College London, London, United Kingdom ^aff066;  National Heart and Lung Institute, Imperial College London, London, United Kingdom ^aff067;  Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland ^aff067;  Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland ^aff068;  Department of Obstetrics & Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore ^aff068;  Department of Obstetrics & Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore ^aff069;  Neonatal Department, Children's Memorial Health Institute, Warsaw, Poland ^aff069;  Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States of America ^aff070;  Neonatal Department, Children's Memorial Health Institute, Warsaw, Poland ^aff070;  Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States of America ^aff071;  NIHR Exeter Clinical Research Facility, College of Medicine and Health, University of Exeter, and Royal Devon and Exeter NHS Foundation Trust, Exeter, United Kingdom ^aff071;  NIHR Exeter Clinical Research Facility, College of Medicine and Health, University of Exeter, and Royal Devon and Exeter NHS Foundation Trust, Exeter, United Kingdom ^aff072;  The Danish Diabetes Academy, Odense, Denmark ^aff072;  The Danish Diabetes Academy, Odense, Denmark ^aff073;  Australian Centre for Precision Health, University of South Australia Cancer Research Institute, Adelaide, Australia ^aff073;  Australian Centre for Precision Health, University of South Australia Cancer Research Institute, Adelaide, Australia ^aff074;  Population, Policy and Practice, UCL Institute of Child Health, University College London, London, United Kingdom ^aff074;  Population, Policy and Practice, UCL Institute of Child Health, University College London, London, United Kingdom ^aff075;  South Australian Health and Medical Research Institute, Adelaide, Australia ^aff075;  South Australian Health and Medical Research Institute, Adelaide, Australia ^aff076;  Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway ^aff076;  Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway ^aff077;  Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland ^aff077;  Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland ^aff078;  Department of Clinical Physiology, Finnish Cardiovascular Research Center—Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland ^aff078;  Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, United Kingdom ^aff079;  Department of Clinical Physiology, Finnish Cardiovascular Research Center—Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland ^aff079;  Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, United Kingdom ^aff080;  MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom ^aff080;  MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College, London, United Kingdom ^aff081;  Center for Pediatric Research, University Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany ^aff081;  Center for Pediatric Research, University Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany ^aff082;  Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany ^aff082;  Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany ^aff083;  CHC–Health Group, Liège, Belgium ^aff083;  CHC–Health Group, Liège, Belgium ^aff084;  Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland ^aff084;  Department of Clinical Chemistry, Finnish Cardiovascular Research Center—Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland ^aff085;  Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland ^aff085;  Institute For Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland ^aff086;  Department of Clinical Chemistry, Finnish Cardiovascular Research Center—Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland ^aff086;  University of Eastern Finland Library Kuopio, Kuopio, Finland ^aff087;  Institute For Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland ^aff087;  Biocenter Oulu, Oulu University Hospital, Oulu, Finland ^aff088;  University of Eastern Finland Library Kuopio, Kuopio, Finland ^aff088;  Universitat Pompeu Fabra (UPF), Barcelona, Spain ^aff089;  Biocenter Oulu, Oulu University Hospital, Oulu, Finland ^aff089;  Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands ^aff090;  Universitat Pompeu Fabra (UPF), Barcelona, Spain ^aff090;  Department of Medicine, Stanford School of Medicine, Stanford, California, United States of America ^aff091;  Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands ^aff091;  Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark ^aff092;  Department of Medicine, Stanford School of Medicine, Stanford, California, United States of America ^aff092;  Department of Public Health, Section of Epidemiology, University of Copenhagen, Copenhagen, Denmark ^aff093;  Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark ^aff093;  National Insitute of Public Health, University of Southern Denmark, Copenhagen, Denmark ^aff094;  Department of Public Health, Section of Epidemiology, University of Copenhagen, Copenhagen, Denmark ^aff094;  National Insitute of Public Health, University of Southern Denmark, Copenhagen, Denmark ^aff095;  Department of Pediatrics, Hvidovre Hospital, Hvidovre, Denmark ^aff095;  The Children’s Obesity Clinic, Department of Pediatrics, Copenhagen University Hospital Holbæk, Holbæk, Denmark ^aff096;  Department of Pediatrics, Hvidovre Hospital, Hvidovre, Denmark ^aff096;  Department of Physiology, University of Turku, Turku, Finland ^aff097;  The Children’s Obesity Clinic, Department of Pediatrics, Copenhagen University Hospital Holbæk, Holbæk, Denmark ^aff097;  Department of Pediatrics, University of Turku, Turku, Finland ^aff098;  Department of Physiology, University of Turku, Turku, Finland ^aff098;  Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center, Groningen, the Netherlands ^aff099;  Department of Pediatrics, University of Turku, Turku, Finland ^aff099;  Paavo Nurmi Centre, Sports and Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland ^aff100;  Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center, Groningen, the Netherlands ^aff100;  Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom ^aff101;  Paavo Nurmi Centre, Sports and Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland ^aff101;  Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, United Kingdom ^aff102;  Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom ^aff102;  Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, United Kingdom ^aff103;  Department of Health Sciences, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands ^aff103;  Child Health Research Centre, University of Queensland, Brisbane, Australia ^aff104;  Department of Health Sciences, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands ^aff104;  World Health Organization, WHO Collaborating Centre for Children’s Health and Environment, Brisbane, Queensland, Australia ^aff105;  Child Health Research Centre, University of Queensland, Brisbane, Australia ^aff105;  Department of Medicine, McMaster University, Hamilton, Canada; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada ^aff106;  World Health Organization, WHO Collaborating Centre for Children’s Health and Environment, Brisbane, Queensland, Australia ^aff106;  Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging NCHA), Leiden, the Netherlands ^aff107;  Department of Medicine, McMaster University, Hamilton, Canada; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada ^aff107;  Bioinformatics Laboratory, Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands ^aff108;  Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging NCHA), Leiden, the Netherlands ^aff108;  Department of Pediatrics, San Paolo Hospital, University of Milan, Milan, Italy ^aff109;  Bioinformatics Laboratory, Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands ^aff109;  Institute of Translational Genomics, Helmholtz Zentrum München–German Research Center for Environmental Health, Neuherberg, Germany ^aff110;  Department of Pediatrics, San Paolo Hospital, University of Milan, Milan, Italy ^aff110;  TUM School of Medicine, Technical University of Munich and Klinikum Rechts der Isar, Munich, Germany ^aff111;  Institute of Translational Genomics, Helmholtz Zentrum München–German Research Center for Environmental Health, Neuherberg, Germany ^aff111;  TUM School of Medicine, Technical University of Munich and Klinikum Rechts der Isar, Munich, Germany ^aff112;  Section of Genomics of Common Disease, Department of Medicine, Imperial College London, London, United Kingdom ^aff112;  Department of Genetics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America ^aff113;  Section of Genomics of Common Disease, Department of Medicine, Imperial College London, London, United Kingdom ^aff113;  Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiologia y Salud Publica-CIBERESP), Barcelona, Spain ^aff114;  Department of Genetics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America ^aff114;  Biodonostia Health Research Institute, San Sebastian, Spain ^aff115;  Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiologia y Salud Publica-CIBERESP), Barcelona, Spain ^aff115;  Subdirección Salud Pública de Gipuzkoa, San Sebastian, Spain ^aff116;  Biodonostia Health Research Institute, San Sebastian, Spain ^aff116;  Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum Muenchen, Munich, Germany ^aff117;  Subdirección Salud Pública de Gipuzkoa, San Sebastian, Spain ^aff117;  University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen N, Denmark ^aff118;  Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum Muenchen, Munich, Germany ^aff118;  Medical Research Council Epidemiology Unit & Department of Paediatrics, University of Cambridge, Addenbrooke’s Hospital, Cambridge, England ^aff119;  University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen N, Denmark ^aff119;  Research Unit for Gynaecology and Obstetrics, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark ^aff120;  Medical Research Council Epidemiology Unit & Department of Paediatrics, University of Cambridge, Addenbrooke’s Hospital, Cambridge, England ^aff120;  University Medical Center Groningen, University of Groningen, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, GRIAC (Groningen Research Institute for Asthma and COPD), Groningen, the Netherlands ^aff121;  Research Unit for Gynaecology and Obstetrics, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark ^aff121;  Department of Pediatrics and Adolescents, Haukeland University Hospital, Bergen, Norway ^aff122;  University Medical Center Groningen, University of Groningen, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, GRIAC (Groningen Research Institute for Asthma and COPD), Groningen, the Netherlands ^aff122;  Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America ^aff123;  Department of Pediatrics and Adolescents, Haukeland University Hospital, Bergen, Norway ^aff123;  Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece ^aff124;  Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America ^aff124;  Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom ^aff125;  Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece ^aff125;  Division of Gastroenterology, Hepatology and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America ^aff126;  Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom ^aff126;  Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland ^aff127;  Division of Gastroenterology, Hepatology and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America ^aff127;  Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland ^aff128;  Department of Cardiology, Heart Center, Tampere University Hospital, Tampere, Finland ^aff128;  Telethon Kids Institute, The University of Western Australia, Perth, Western Australia, Australia ^aff129;  Department of Cardiology, Heart Center, Tampere University Hospital, Tampere, Finland ^aff129;  Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Inner City Clinic, University Hospital Munich, Ludwig-Maximilians-Universität of Munich, Munich, Germany ^aff130;  Telethon Kids Institute, The University of Western Australia, Perth, Western Australia, Australia ^aff130;  Allergy and Lung Health Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia ^aff131;  Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Inner City Clinic, University Hospital Munich, Ludwig-Maximilians-Universität of Munich, Munich, Germany ^aff131;  Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain ^aff132;  Allergy and Lung Health Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia ^aff132;  Amsterdam Public Health research institute and Amsterdam Reproduction & Development research Institute, Amsterdam, the Netherlands ^aff133;  Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain ^aff133;  Oxford National Institute for Health Research (NIHR) Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom ^aff134;  Amsterdam Public Health research institute and Amsterdam Reproduction & Development research Institute, Amsterdam, the Netherlands ^aff134;  Center for Spatial and Functional Genomics, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America ^aff135;  Oxford National Institute for Health Research (NIHR) Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom ^aff135;  Center for Spatial and Functional Genomics, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America ^aff136
Vyšlo v časopise: Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits. PLoS Genet 16(10): e32767. doi:10.1371/journal.pgen.1008718
Kategorie: Research Article
doi: https://doi.org/10.1371/journal.pgen.1008718