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Subcutaneous pdC1-INH in Patients with Hereditary Angioedema in Real-World Practice
Italian authors published a series of cases of patients with hereditary angioedema caused by C1 inhibitor deficiency (C1-INH-HAE) with long-term prophylaxis using human plasma-derived C1 inhibitor concentrate (pdC1-INH) in subcutaneous form. They supplement the results of the placebo-controlled COMPACT study, in which s.c. pdC1-INH reduced the frequency of attacks, with insights from real-world practice in 5 patients treated at the angioedema therapy center in Milan, Italy.
Efficacy and Safety of an Activated FXII Inhibitor in Preventing HAE Attacks
Hereditary angioedema (HAE) is a rare, potentially life-threatening inherited disorder characterized...
To what extent does the delay between symptom onset and diagnosis of AATD affect patient survival?
The risk of chronic obstructive pulmonary disease (COPD) is increased, among other things, by a deficiency...
Augmentation Therapy of Bronchiectasis Due to AATD – Case Report
Alpha-1-antitrypsin deficiency (AATD) is a rare cause of bronchiectasis unrelated to cystic fibrosis....
Pregnancy and Childbirth in a Woman with VWD − A Case Study
Pregnancy and childbirth are relatively demanding periods and situations for women with von Willebrand...
Benefits and Cost-Effectiveness of Superabsorbent Dressings in the Treatment of Venous Leg Ulcers
A recent cost-effectiveness analysis based on German data showed that using superabsorbent…
Brain implants can affect the human mind in a surprising way
The technology company Neuralink, owned by Elon Musk, announced in December 2022 that it plans to…
Absorption of Levothyroxine: What Has the New Formulation of LT4-Containing Medicinal Products Brought?
Lifelong use of levothyroxine (LT4) is the cornerstone of hypothyroidism treatment. The narrow…
What situations can arise in PBC treatment with obeticholic acid? Answers provided by case studies from real practice at CKTCH
The Hradec Gastroenterology Days 2023 were traditionally held in March at the Educational Center of…
Subclinical Hypothyroidism in Pregnancy: How Great Are the Real Risks and Can They Be Effectively Reduced?
The aim of the meta-analysis by authors from the Mayo Clinic was to describe the impact of…
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