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Colours of Sepsis 2023: Antimicrobial Stewardship is a Necessity. The Spectrum of Effective Antimicrobial Modalities has Expanded to Include Another Combination

9. 2. 2023 Source: Anti-Infectives

Inappropriate antibiotic (ATB) treatment is associated with high mortality, while unrestricted use of broad-spectrum antibiotics drives resistance development. Thus, the decision to deploy antibiotics becomes a choice between the current and future patient. Antimicrobial stewardship (AMS) is an essential strategy in daily operations. Extending the spectrum of antimicrobial agents is equally crucial in combatting resistant bacterial strains. A symposium on this theme was part of the expert program at this year's 'festival of intensive medicine'…

Proton radiotherapy means lower risk with high efficacy of radiation. The key is getting the patient into the treatment process as soon as possible

The Proton Therapy Center in Prague (PTC −⁠ Proton Therapy Center Czech) is a modern healthcare facility specializing in the treatment of oncological diseases using so-called proton radiotherapy. This…

8. 2. 2023 Source: Proton Radiotherapy

The Unexpected Rise of Telemonitoring During the COVID-19 Pandemic

The COVID-19 pandemic, despite many negative impacts, also brought positive benefits to patients' health in a rather unexpected direction. Prior to the coronavirus pandemic, monitoring basic vital…

8. 2. 2023 Source: proLékaře.cz

case studies ikona pro unikátní sekci pro IPP téma

CASE STUDIES on the topic of progressing interstitial lung processes

This page serves as a hub for case studies on the topic of progressing interstitial processes. The case studies aim to provide a multidisciplinary view on the rare disease topic of IPP.

7. 2. 2023 Source: Progressive Interstitial Pulmonary Processes

Transthyretin –⁠ More Than a Thyroxine Transporter

Transthyretin (TTR) is an extracellular protein whose main role is to transport thyroxine and retinol in the body and brain. TTR tends to form amyloid deposits, which can lead to systemic disease…

6. 2. 2023 Source: Amyloidosis

Patient with a History of DOAC Usage in Neurological ICU with Stroke –⁠ Case Study

How should we approach patients with a stroke who are taking direct oral anticoagulants (DOACs) and correctly assess the situation? When should we administer the available antidote according to…

1. 2. 2023 Source: Anticoagulant Treatment

Critical Overview of Clinical Studies on EHL FVIII Preparations

An international team of experts recently published a comprehensive work evaluating the methodology used in clinical trials of various extended half-life (EHL) factor VIII (FVIII) products. Their…

1. 2. 2023 Source: Hemophilia

Overview of Regimen Measures for House Dust Mite Allergy

House dust mite allergy is one of the significant causes of respiratory allergies in both children and adult patients. In addition to pharmacological treatment, the cornerstone of therapy also…

31. 1. 2023 Source: Dust Mite Allergy

Long-term Safety of Dupilumab in Adult Patients with Moderate to Severe Atopic Dermatitis

Moderate to severe atopic dermatitis (AD) often requires systemic therapy. The long-term safety of dupilumab in patients with this condition was evaluated in an open-label extension (OLE) of the…

24. 1. 2023 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation

Treatment of Tumors Using Ultrasound? The First Results of the Use of Histotripsy Look Promising

Histotripsy represents a new therapeutic method that allows the non-invasive removal of tumor tissue using the principle of so-called ultrasound cavitation. The method has been successfully tested in…

24. 1. 2023 Source: proLékaře.cz

Tiapride versus Haloperidol in the Therapy of Aggressiveness and Agitation in Elderly Patients with Cognitive Impairment

Acute restlessness, agitation, and aggression can be associated with psychiatric disorders but also be manifestations of somatic illnesses. Psychomotor agitation combined with disorientation is…

19. 1. 2023 Source: Viral infections

Non-Invasive Diagnosis of Cardiac Amyloidosis

Cardiac amyloidosis has always been considered a rare pathology. However, thanks to advancements in imaging methods and laboratory tests, it is now evident that it might be responsible for a larger…

16. 1. 2023 Source: Amyloidosis

Memantine, Acetylcholinesterase Inhibitors, and Their Combination in the Treatment of Alzheimer's Disease −⁠ Findings from Meta-Analyses

Is memantine, an acetylcholinesterase inhibitor (donepezil), or their combination more advantageous in the therapy of Alzheimer's disease? Two meta-analyses tried to answer this question, and we…

12. 1. 2023 Source: Cognitive in the treatment of Alzheimer's disease

Long-term Efficacy, Safety, and Tolerability of Normal Human IgG with Facilitated Absorption in Patients with Humoral Immunodeficiency

The treatment of patients with humoral immunodeficiency is long-term and therefore needs to be not only effective but also safe and well-tolerated. Below, we present the outcomes from an Italian…

12. 1. 2023 Source: Primary and Secondary Immunodeficiencies

fSCIG in Elderly Patients with PID or SID in Real Clinical Practice

The work of a team of German and Dutch authors presents data on the real clinical use of 10% subcutaneous immunoglobulin facilitated by hyaluronidase (fSCIG) in elderly patients with primary (PID) or…

12. 1. 2023 Source: Primary and Secondary Immunodeficiencies

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