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Tool for Predicting Cardiometabolic Risk in Young Patients with Psychotic Disorder

13. 12. 2022 Source: Modern Treatment of Schizophrenia

A study describing the development and validation of an algorithm for predicting cardiometabolic risk in patients with psychotic disorder, PsyMetRiC (Psychosis Metabolic Risk Calculator), was recently published in Lancet Psychiatry. British scientists have created a tool to estimate the risk of developing metabolic syndrome over the next 6 years, serving as a predictor of cardiovascular morbidity and mortality in young people with psychosis aged 16–35 years.

Viral or Bacterial Etiology? Old Question, New Methods...

The gold standard in the differential diagnosis of viral and bacterial respiratory infections is primarily C-reactive protein (CRP), followed by procalcitonin and interleukins. What are the pitfalls…

13. 12. 2022 Source: Cough Therapy

When You Say Amyloid…

The term 'amyloid' was first used by the German doctor Rudolf Virchow in the mid-19th century. He described it as a pathological substance which he originally thought was starch. Although it was…

12. 12. 2022 Source: Amyloidosis

Practical Experiences Using ZULP in Cardiology

The application of a product containing ferric carboxymaltose (FCM) or the use of a contrast agent with sulfur hexafluoride in microbubbles are examples of the use of specially accounted medicinal…

12. 12. 2022 Source: Chronic Heart Failure and Lipidology

How Will the New Player in Dyslipidemia Therapy Change the "Rules of the Game"?

Inclisiran, as an innovative drug indicated for adult patients with primary hypercholesterolemia or mixed dyslipidemia, was registered in the European Union at the end of 2020. Internists and…

12. 12. 2022 Source: Chronic Heart Failure and Lipidology

Undiagnosed Hereditary Angioedema in Pregnancy –⁠ Case Study

Delayed diagnosis or misdiagnosis is not uncommon with hereditary angioedema (HAE), especially during pregnancy and the postpartum period. A case study by Canadian authors illustrates that HAE should…

8. 12. 2022 Source: Hereditary Angioedema

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Successful Long-Term Subcutaneous Prophylaxis of Hereditary Angioedema –⁠ Case Study

Hereditary angioedema (HAE), arising from a deficiency of C1 inhibitor (C1-INH), clinically manifests as swelling of the subcutaneous tissue and mucous membranes. The standard prophylactic therapy…

8. 12. 2022 Source: Hereditary Angioedema

Biochemotherapy of Aggressive Rectal Carcinoma –⁠ A Case Study from the Czech Republic

Colorectal cancer arises from a complex interplay of environmental and lifestyle factors complemented by hereditary factors. Nowadays, it represents not only a health concern but also a socioeconomic…

7. 12. 2022 Source: Colorectal Cancer

Incidence of Secondary Malignancies in CLL Patients on FCR Regimen in Central Europe

Chronic lymphocytic leukemia (CLL) represents the most common type of leukemia in Western countries with closely related incidence in Central European states. Since 2000, new therapeutic regimens…

7. 12. 2022 Source: Chronic Lymphocytic Leukemia

Pathogenetic Mechanisms Underlying the Development and Progression of Interstitial Lung Diseases

Interstitial lung processes (ILP) represent an umbrella term for a wide range of nosological units that differ from each other in clinical course, prognosis, and pathogenesis. Most ILPs are…

6. 12. 2022 Source: Progressive Interstitial Pulmonary Processes

Finding Balance Between Intracranial Efficacy and Adverse Effects of ALK Kinase Inhibition

More than 7 years –⁠ that is the current median survival of patients with non-small cell lung cancer (NSCLC) with a mutation in the anaplastic lymphoma kinase (ALK) gene who are receiving targeted…

6. 12. 2022 Source: Genetic Profile and Treatment of NSCLC

What did the first data from the pilot lung cancer screening show?

Czech pulmonologists have released the first interim results of this year's pilot testing of heavy smokers due to the risk of lung cancer. More than 4,000 patients passed through the hands of general…

5. 12. 2022 Source: MDT Board

Presence of Risk Factors Associated with Colectomy in Patients with Ulcerative Colitis in Studies with Tofacitinib

One of the important goals of active ulcerative colitis therapy is the prevention of colectomy. A clinical study, the results of which were recently presented at the Vienna UEG (United European…

4. 12. 2022 Source: Intestinal Inflammations

Prof. Petr Marusič: Is the Success of Therapy Changing with the Arrival of New Antiepileptics?

At the XXV. postgraduate course in epileptology, 'Jiří Dolanský Days', prof. MUDr. Petr Marusič, Ph.D., from the Neurological Clinic of the 2nd Faculty of Medicine, Charles University, and Motol…

2. 12. 2022 Source: Epilepsy

Severe Polytrauma in a Man with von Willebrand Disease −⁠ Case Report

The authors of a recently published case report present a case of multiple trauma (including brain injury) in a young man with von Willebrand disease (vWD) type 2A, in whom repeated administration of…

29. 11. 2022 Source: Von Willebrand Disease

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