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Rare Diseases in Neurology

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Efficacy and Safety of Fenfluramine in the Treatment of Lennox-Gastaut Syndrome – An Overview of Current Knowledge

21. 6. 2024 Source: Rare Diseases in Neurology

In a recently published article, British authors summarize the current knowledge on the efficacy and safety of fenfluramine (FFA) in the treatment of Lennox-Gastaut syndrome (LGS, a developmental and epileptic encephalopathy). In addition to the reduction in seizure frequency demonstrated in clinical studies, they discuss the impact of fenfluramine on reducing the risk of sudden unexpected death in epilepsy (SUDEP), improving cognitive function in patients, and its safety concerning weight loss and heart disorders.

epile

Spectrum of Mechanisms of Action of Fenfluramine in the Treatment of Rare Epilepsies

Fenfluramine (FFA) is an anticonvulsant used in the treatment of rare epilepsies such as Dravet…
21. 6. 2024 Source: Rare Diseases in Neurology
myastevia gravis

Subcutaneous zilucoplan – the end of necessary “trips” to the hospital for myasthenia gravis patients?

A study recently published in Lancet Neurology demonstrated the efficacy and safety of the…
3. 4. 2024 Source: Rare Diseases in Neurology

Articles on this topic
dedecek a sestricka

Advances in the Treatment of Myasthenia Gravis on the Horizon

The research of new drugs for the generalized form of myasthenia gravis has made significant…
28. 3. 2024 Source: Rare Diseases in Neurology
syndrom Dravetové

Improvement of Executive Functions in Therapy of Dravet Syndrome with Fenfluramine in Preschool Children

Dravet syndrome is a rare genetic progressive epileptic encephalopathy that is usually…
10. 10. 2023 Source: Rare Diseases in Neurology
Myasthenia gravis_žena

Myasthenia Gravis and Unmet Patient Needs – Data from Clinical Practice

Myasthenia gravis (MG) is a rare, chronic, disabling, unpredictable, and potentially…
10. 10. 2023 Source: Rare Diseases in Neurology
syndrom dravetové

When to Suspect Dravet Syndrome?

In 2022, an international consensus panel of experts on the diagnosis and treatment of Dravet…
29. 6. 2023 Source: Rare Diseases in Neurology
myasthenia gravis

Medication in Patients with Myasthenia Gravis – What to Watch Out For?

According to current recommendations, the treatment of myasthenia gravis (MG) should be…
29. 6. 2023 Source: Rare Diseases in Neurology
Syndrom Dravetové

Dravet Syndrome – Get to Know It

Dravet syndrome is a severe myoclonic epilepsy occurring in early childhood. It is classified…
2. 5. 2023 Source: Rare Diseases in Neurology
Bolest svalů_muž

When and why to consider the diagnosis of myasthenia gravis in neurological practice, and what treatment options do we currently have?

Myasthenia gravis (MG) is a clinically heterogeneous disease characterized by fluctuating…
2. 5. 2023 Source: Rare Diseases in Neurology

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