Vplyv systémovej enzýmovej terapie na hojenie jazvy po cisárskom reze

English version

Autoři: Erik Dosedla ¹ ; A. Grendelova ¹; P. Calda ²
Působiště autorů: Department of Obstetrics and Gynecology, P. J. Safarik University, 1st Private Hospital Košice-Šaca Inc., Košice-Šaca, Slovak Republic ¹; Charles University, Prague, First Faculty of Medicine and General Teaching Hospital, Department of Gynecology and Obstetrics, Prague, Czech Republic ²
Vyšlo v časopise: Ceska Gynekol 2016; 81(3): 202-207

Souhrn

Ciele:
Cieľom našej štúdie bolo sledovať zmeny v hojení uterotomických jaziev po cisárskom reze u pacientiek užívajúcich systémovú enzymoterapiu v porovnaní s pacientkami, ktoré neužívali systémovú enzymoterapiu (Wobenzym).

Metodika:
Prospektívna kohortová štúdia bola vykonaná u 60 prvorodičiek, ktoré rodili cisárskym rezom. Porovnávali sme nasledovné premenné: hrúbku jazvy po cisárskom reze, koeficient dehiscencie (DRC), závažnosť defektu jazvy po cisárskom reze, dilatáciu dutiny maternice, pooperačnú bolesť, C-reaktívny proteín a telesnú teplotu pacientiek.

Výsledky:
Hrúbka jazvy 6 týždňov po cisárskom reze bola významne väčšia v skupine pacientiek, ktoré dostávali Wobenzym (7,1 ± 0,9 mm; priemer ± SD), ako u pacientiek bez Wobenzymu (5,3 ± 0,7 mm) (p = 0,01). Ťažký defekt jazvy po cisárskom reze bol pozorovaný u jednej užívateľky Wobenzymu (1/30, 3,3 %) a u 5 žien (5/30, 16,7 %), ktoré Wobenzym neužívali, a teda nešlo o štatisticky významný rozdiel (p = 0,195).

Záver:
Napriek tomu, že v skupine pacientiek užívajúcich Wobenzym bolo menej ťažkých defektov jaziev po cisárskom reze, rozdiel nedosiahol štatistickú významnosť, čo možno pripísať malému súboru pacientiek.

Kľúčové slová:
enzymoterapia, cisársky rez, ultrazvuk, jazva po cisárskom reze

Zdroje

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