Early and late morbidity and mortality in twins born between 24th and 36th gestational week in and outside perinatology center

Czech version

Authors: D. Bařinová ¹; J. Pavlíček ^2,3; I. Matyáštíková ¹; V. Sobolová ¹; A. Střídová ¹; K. Sitárová ¹; P. Zárubová ¹; H. Wiedermannová ^1,3; H. Burčková ¹; A. Piegzová ⁴
Authors‘ workplace: Oddělení neonatologie, FN Ostrava ¹; Klinika dětského lékařství, FN Ostrava ²; Lékařská fakulta, Ostravská univerzita ³; Gynekologicko-porodnická klinika, FN Ostrava ⁴
Published in: Čes-slov Pediat 2020; 75 (3): 146-153.
Category: Original Papers

Overview

Aim: Study of early and late morbidity and mortality in neonates from twin pregnancy. Analysis of these factors in relation to gestational week and birth in a perinatal care center or outside it.

Methods: The retrospective analysis was conducted between 2008 and 2017 in the Moravian-Silesian Region. Data was acquired from medical records of the University Hospital Ostrava and from the records of general practitioners for children. The early and late morbidity and mortality were monitored in groups according to gestational weeks. The patients were divided into those born in a perinatal care center and outside it, followed by transport into the University Hospital Ostrava.

Results: During the study years, a total of 1,464 children from twin pregnancies born between the 24th and 36th gestational week were hospitalized in the University Hospital Ostrava. In the perinatal care center, 93% (1,364/1,464) of newborns were born and 7% (100/1,464) were transported to the University Hospital Ostrava from other hospitals. The most common diseases observed in the early period were respiratory distress syndrome in 25% (365/1,464) and bronchopulmonary dysplasia in 7% (99/1,464) of cases. Concerning late morbidity, the most commonly observed condition was growth retardation, found in 3% (32/1,209) of children. The early neonatal mortality rate was 0.4% (6/1,464). In the group of children born outside the perinatology center, there was a significantly higher incidence of intraventricular hemorrhage Grade III and IV (p=0.004) and cerebral palsy (p=0.005) in very preterm neonates.

Conclusion: Centralization of perinatal care is essential in providing care for preterm newborns. This is emphasized in multiple pregnancies, which tend to be more premature, and the children are at greater risk of morbidity and mortality.

Keywords:

morbidity – newborn – Twins – prematurity – neonatal mortality

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