Výběr dárců pro multikomponentní odběry krve

Selection of blood donors for the multicomponent blood collection

Introduction.
Multicomponent collection belongs to the modern alternative of the blood donation. Uniform criteria for selection of donors have not been established yet. The aim of this study was to specify these criteria.

Methods.
The reciprocal analysis of entry parameters, apheretic parameters, and quality of blood components were compared in performed multicomponent collections. Significance of selected criteria for individual types of multicomponent collections was evaluated.

Results.
Two hundred fifty collections were performed in 137 blood donors using Haemonetics MCS+ separator and 44 collections using TRIMA Accel separator (2 unit red cell apheresis and combined thrombocytapheresis). The collections lasted from 31 to 81 minutes according to the type of protocol. The collected volume was 7 to 13 % from the total blood volume (TBV) in both separators, and the quality of components met required criteria. Using TRIMA Accel, the mean platelet count in blood donors before donation was significantly lower, and TBV did not affect duration of apheresis nor quality of the components.

Discussion.
Results of this study indicate the necessity of the selection of blood donors in accordance to both devices and protocols. Key factor for the selection of blood donors for combined thrombocytapheresis is platelet count before donation. The value of TBV is one of the limiting factors particularly for selection of the volume of the components. Selection criteria of Council of Europe for 2 unit red blood cell apheresis are necessary to be completed about monitoring of blood donor storage iron.

Key words:
multicomponent blood collection, selection criteria for donors, quality of blood components