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Benefit of Adding Empagliflozin to Standard Therapy in Heart Failure with Reduced Ejection Fraction

5. 8. 2022 Source: Heart Failure

The use of empagliflozin led to a reduction in the risk of hospitalization for heart failure or death from cardiovascular (CV) causes in the EMPEROR-Reduced study in patients with adequately treated heart failure with reduced left ventricular ejection fraction (HFrEF) compared to placebo, regardless of whether the patients had diabetes. A post hoc analysis of this study focused on another important question: how does the benefit of adding empagliflozin interact with the standard disease-modifying therapy for heart failure?

Sequential administration of immunochemotherapy and venetoclax after failure of BCR inhibitor treatment –⁠ interactive video case study

The treatment of chronic lymphocytic leukemia (CLL) is evolving. What was impossible years ago is now becoming a reality. From chemotherapy, through immunochemotherapy, to the use of molecules…

5. 8. 2022 Source: Chronic Lymphocytic Leukemia

Hydroresponsive Dressings for Acute and Hard-to-Heal Wounds

A recently published review of clinical evidence from nearly three dozen studies demonstrates successful debridement and cleansing of various hard-to-heal wounds using HydroClean hydroresponsive…

4. 8. 2022 Source: Wound Healing

Prediabetes through the lens of current data and findings −⁠ and why hurry with intervention

Type 2 diabetes mellitus (DM2) is one of the most common causes of premature morbidity and mortality worldwide. The most serious impact on the health of the organism is mainly due to the…

27. 7. 2022 Source: Diabetes

Discontinuation of Methotrexate After Initiation of Tofacitinib in the Treatment of Rheumatoid Arthritis

New real-world data show that in patients with rheumatoid arthritis (RA) who started treatment with tofacitinib combined with oral methotrexate (MTX), it is possible to discontinue MTX and achieve…

27. 7. 2022 Source: Arthritis

Incidence of CV Events, Malignancies, and Venous Thromboembolism in Patients with RA According to Baseline CV Risk and Administered Treatment

An international team of experts evaluated the impact of cardiovascular (CV) risk on the incidence and risk of major CV events, malignancies, and venous thromboembolism (VTE) in patients with…

27. 7. 2022 Source: Arthritis

Increase in Hematocrit During Empagliflozin Treatment in a Diabetic Patient with Severe Anemia −⁠ A Case Study

In a case study involving a 78-year-old diabetic patient, where only the administration of empagliflozin led to the correction of severe anemia of unknown origin, Polish authors demonstrate the…

26. 7. 2022 Source: Heart Failure

Composition of the Intestinal Microbiota of Patients with IBS May Predetermine the Success of a Diet with Low Fermentable Carbohydrates

Some patients with irritable bowel syndrome may benefit from a diet low in fermentable carbohydrates, but the mechanism of this intervention is not yet satisfactorily explained. A study published in …

23. 7. 2022 Source: Irritable Bowel Syndrome

Can the use of sartans reduce mortality and severity of COVID-19 in hypertensives?

Existing scientific and clinical evidence suggests the involvement of the renin-angiotensin-aldosterone system (RAAS) in the pathophysiology of COVID-19. Some of the initial experimental therapy…

21. 7. 2022 Source: Sartans in the Treatment of Hypertension

Diagnosis of Skin Malignancies via Mobile Application Successfully Tested in the UK

Skin malignancies are a significant global cause of morbidity and mortality, with melanoma responsible for most deaths, and its incidence is increasing faster than any other cancer. Early detection…

21. 7. 2022 Source: proLékaře.cz

konzultace s mladými muži o rakovině prostaty

Early Detection of Erectile Dysfunction in Men with Type 2 Diabetes

A retrospective study published last year identified predictors of erectile dysfunction in men with type 2 diabetes. The authors recommend screening patients with elevated uric acid levels, diabetes…

18. 7. 2022 Source: Diabetes

Inosine Pranobex in the Treatment of Cervical HPV Infections

The aim of the review article published in the journal Infection and Drug Resistance was to evaluate the available data on the potential use of inosine pranobex in the treatment of patients with a…

13. 7. 2022 Source: Viral infections

Influence of ARNI on the Efficacy and Safety of Empagliflozin in the Treatment of Heart Failure with Reduced Ejection Fraction

Pharmacological inhibition of neprilysin and the AT1 receptor for angiotensin II (ARNI) through sacubitril/valsartan reduces cardiovascular (CV) mortality and the risk of hospitalization for heart…

13. 7. 2022 Source: Heart Failure

Autonomic Dysfunction in Patients with Transthyretin Amyloidosis

Autonomic nervous system disorders are a common complication of transthyretin amyloidosis. Their frequency, nature, and impact on patients' quality of life were examined in the longitudinal THAOS…

12. 7. 2022 Source: Amyloidosis

Overview of Current Treatment Options for MRSA-Induced Pneumonia

Pneumonia caused by methicillin-resistant strains of Staphylococcus aureus (MRSA) remains a disease with high mortality requiring urgent treatment, whether it is a community-acquired or nosocomial…

8. 7. 2022 Source: Anti-Infectives

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