News
Prognostic Significance of Mutations in Maintenance Hypomethylation Therapy for AML Patients
A recently published sub-analysis of the QUAZAR AML-001 clinical trial evaluated the efficacy of maintenance treatment for acute myeloid leukemia (AML) with oral azacitidine, considering the initial mutational status of NPM1 and FLT3 genes and the presence of minimal residual disease (MRD) in patients after the completion of intensive chemotherapy.
Current Recommendations by the ELN Expert Panel on AML Diagnosis Management
The 2022 recommendations from European LeukemiaNet (ELN) add new information to the previous…
Overuse of Corticosteroids as a Serious Problem in ITP
Corticosteroids (CS) are a common part of the treatment for immune thrombocytopenia (ITP). However,…
Romiplostim in Life-Threatening Bleeding Situations − Case Reports
Immune thrombocytopenic purpura, or immune thrombocytopenia (ITP), typically manifests as bleeding…
CYP Enzyme? Cytochrome P450 2D6 and Drug Metabolism
The CYP2D6 isoenzyme of cytochrome P450 participates in the metabolism of approximately 20% of commonly...
Association of M2 Haplotype of the Annexin A5 Gene with Recurrent Reproductive Losses
Annexin A5 (ANXA5) is a placental anticoagulant protein that ensures adequate blood supply to the…
Etiology of Recurrent Reproductive Losses – Focus on Genetics
Repeated pregnancy losses pose a significant threat to a woman's physical and mental health. The…
Li-Fraumeni Syndrome – Indication for Testing and Recommended Surveillance
A germline mutation of the TP53 gene, which causes Li-Fraumeni syndrome, results in a congenital predisposition...
Water Microjet as a Gentler Method of Debridement
Debridement is an integral part of chronic wound treatment. Currently, the most common method is…
Popular this week
- Where did COVID come from? Are infected animals or a lab leak to blame for the pandemic?
- New Algorithm to Enhance Prediction of Cardiovascular Disease Risk
- Influence of some anesthetics and sedatives on source of sexual hallucination: undervalued forensic risk for doctors
- Target blood pressure values in heart failure
- Using propofol − what is forbidden, is not (really) allowed ... or what are we risking if we use it in contradiction with the SPC?