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Bimekizumab in the treatment of moderate to severe hidradenitis suppurativa –⁠ another approved indication for this biological agent

1. 7. 2024 Source: Psoriasis

In May, the primary results of the BE HEARD I and II studies evaluating the efficacy and safety of the IL-17A and IL-17F inhibitor bimekizumab in the treatment of moderate to severe hidradenitis suppurativa (HS) in adults were published in The Lancet. This is the first publication of the results of these Phase III studies. Based on these findings, the European Medicines Agency (EMA) approved bimekizumab (which is currently approved for the treatment of plaque psoriasis, psoriatic arthritis, and axial spondyloarthritis) for the treatment of HS…

Reducing Overall Mortality by Combining Three Antihypertensives into a Single Pill

Treating hypertension to recommended target blood pressure values often requires a combination of three antihypertensives. By simply combining these three substances into a single pill, it is…

26. 6. 2024 Source: Risk factors of cardiovascular diseases

What Benefits Do Modern Antidiabetics Bring to Patients in Primary Care?

How has the life of patients who now have the opportunity to treat diabetes mellitus in general practice changed? And what do the current prescription conditions for modern antidiabetics bring to…

21. 6. 2024 Source: Modern Treatment of Diabetes with GLP-1 Analogues

Current European Recommendations for the Treatment of Renal Colic Due to Urolithiasis

At the annual congress in Milan in 2023, new recommendations from the European Association of Urology (EAU) for the acute treatment of patients with renal colic were presented. We summarize the key…

21. 6. 2024 Source: Analgesia

MD Šimon Kozák: In algology, nothing works miraculously overnight! It is important to seek advice from specialists

Why is it not advisable to rely on one method in pain treatment? What about patients with a mixed type of pain, whose numbers are increasing? And why shouldn’t surgical solutions for back pain be the…

21. 6. 2024 Source: Analgesia

Efficacy and Safety of Fenfluramine in the Treatment of Lennox-Gastaut Syndrome –⁠ An Overview of Current Knowledge

In a recently published article, British authors summarize the current knowledge on the efficacy and safety of fenfluramine (FFA) in the treatment of Lennox-Gastaut syndrome (LGS, a developmental and…

21. 6. 2024 Source: Rare Diseases in Neurology

Spectrum of Mechanisms of Action of Fenfluramine in the Treatment of Rare Epilepsies

Fenfluramine (FFA) is an anticonvulsant used in the treatment of rare epilepsies such as Dravet syndrome and Lennox-Gastaut syndrome. In addition to effectively reducing seizure frequency, it also…

21. 6. 2024 Source: Rare Diseases in Neurology

Hybrid Cooperating Complexes in Osteoarthritis Treatment

Intra-articular application of corticosteroids and hyaluronic acid is part of the treatment of osteoarthritis (OA) in patients for whom oral or topical treatment does not provide sufficient response.…

21. 6. 2024 Source: Pain Management

Possibilities of Cannabis Use in Tourette Syndrome Therapy

A retrospective analysis and online survey conducted at a psychiatric clinic in Hanover, Germany, investigated the effectiveness and safety of using cannabis products in patients with Tourette…

20. 6. 2024 Source: Medical Cannabis

Bimekizumab in the Treatment of Psoriatic Arthritis

Arthritis can appear in up to a third of patients with psoriasis, mostly after the onset of skin symptoms. Early recognition of this transition by dermatologists and general practitioners is crucial,…

20. 6. 2024 Source: Rheumatic Diseases

With Dr. Miroslav Nečas, Ph.D., on the conclusions of the recent consensus of the expert panel on the practice of biological treatment of psoriasis

This February, an expert consensus on the use of bimekizumab in the treatment of psoriasis and psoriatic arthritis (PsA) was published based on a literature review of 102 articles, from which 19…

19. 6. 2024 Source: Rheumatic Diseases

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