Practical experience with dapagliflozin: case reports

Czech version

Authors: Viliam Vaník ¹; Zbynek Schroner ²
Authors‘ workplace: Diabetologická ambulancia, Nemocnica Svet zdravia, Svidník ¹; Lekárska fakulta, Univerzita Pavla Jozefa Šafárika v Košiciach ²
Published in: Diab Obez 2023; 23(45): 37-42
Category: Case studies

Overview

In addition to glycemic control, the main goal of comprehensive treatment of type 2 diabetes mellitus is to reduce overall cardiovascular and renal risk. The cardioprotective and renoprotective effect of SGLT2 inhibitors (SGLT2i) has been confirmed in recently completed clinical trials even in non-diabetic patients. Two case reports from routine clinical practice in the Slovak Republic discuss the effect of one of the SGLT2i – dapagliflozin in a patient with type 2 diabetes mellitus (DM2T) and concomitant chronic kidney disease, and also in a patient with DM2T without cardiovascular disease but with cardiovascular risk factors already present. Both case reports demonstrate that the effect of treatment with this group of pharmaceuticals is very pronounced and, above all, early.

Keywords:

type 2 diabetes mellitus – chronic kidney disease – SGLT2 inhibitor – dapagliflosin

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