Use of albumin in newborns

Czech version

Authors: L. Časnocha Lúčanová
Published in: Čes-slov Neonat 2024; 30 (2): 81-87.
Category: Reviews

Overview

Use of albumin in newborns

Albumin is the most important plasma protein. Hypoalbuminemia in critically ill newborn infants occurs due to reduced synthesis, increased losses or redistribution of albumin. Intravenous treatment with exogenous albumin is administered in newborns in cases of hyperbilirubinemia, hypovolemia, hypoalbuminemia or in protein-losing states. However, its administration is often inappropriate and can be associated with possible harms such as fluid overload, neurological injury, or renal injury. Currently, albumin administration is not recommended in the treatment of neonatal hyperbilirubinemia, volume resuscitation in the delivery room, or in the routine treatment of hypoalbuminemia in preterm infants.

Keywords:

Resuscitation – albumin – hyperbilirubinemia – hypoalbuminemia – volume expansion

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Article was published in

Czech and Slovak Neonatology

2024 Issue 2