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FLEX –⁠ A New Predictive Model for Assessing Follicular Lymphoma Risks

14. 11. 2020 Source: Non-Hodgkin Lymphomas and CLL

Overall survival of patients with advanced-stage follicular lymphoma (FL) who experience early disease progression after chemotherapy remains low. Currently used clinical prognostic models do not provide optimal sensitivity and specificity for identifying this patient subgroup. The presented study by an international team of authors introduced a new assessment index that achieves better outcomes.

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Socio-economic Benefits of Using Obinutuzumab in 1st Line Treatment of Follicular Lymphoma

Pharmacoeconomic analyses remind us that our patients' diseases affect not only themselves or the healthcare system, but also have an impact on the entire society. Patients with follicular lymphoma…
14. 11. 2020 Source: Non-Hodgkin Lymphomas and CLL

Expression of PD-L1 in Patients with Advanced Non-Small Cell Lung Cancer

An international team of authors published a systematic review addressing the relationship between the programmed cell death receptor ligand (PD-L1) and important clinical characteristics of patients…
14. 11. 2020 Source: Immunotherapy in Oncology
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Case Study with Voting: Intensification of Type 2 Diabetes Therapy in a Chronically Treated Patient. How to Proceed According to Current Recommendations?

We have prepared an interactive case study for you with a 70-year-old patient with decompensated Type 2 Diabetes. The patient was diagnosed with DM eight years ago. What treatment approach would you choose?...
12. 11. 2020 Source: Diabetes
dítě spánek štěstí dětství kluk

Levodropropizine vs. dextromethorphan: Which one to recommend to your patients and why?

Reducing cough intensity and nighttime awakenings, rapid onset of action, simple dosing regimen, and good treatment tolerance—these are the properties we expect from antitussive drugs, not only in…
12. 11. 2020 Source: Cough Therapy
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COVID Pneumonia: How Can Erdosteine Help and What Did a Clinical Study Suggest?

When patients who have recovered from COVID pneumonia begin home treatment, they are often far from being symptom-free. General practitioners and outpatient pulmonologists often have to address these…
12. 11. 2020 Source: Cough Therapy
Sportovec v kyslíkové masce běžící na běžeckém pásu a zdravotník

Improving Physical Function in Patients with COPD in Routine Clinical Practice

The increase in exercise capacity with the use of a fixed-dose combination of tiotropium and olodaterol in the Respimat inhaler has already been demonstrated in clinical studies in patients with chronic...
9. 11. 2020 Source: COPD
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Prostate Health Index and its Possible Use in Clinical Practice

With the increasing incidence of prostate cancer, the effort to improve its diagnostics is also growing. The exclusively used and practice-proven prostate-specific antigen (PSA) continues to play an…
9. 11. 2020 Source: Prostate Health Index
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Levothyroxine and the Interchangeability of Preparations Containing It

Levothyroxine is a synthetic thyroid hormone used to treat patients with hypothyroidism, which affects approximately 1-2% of the younger population and increases with age, especially in women.…
6. 11. 2020 Source: Thyroid Disorders
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Desirable Side Effects of Antidiabetics

The days when diabetology was a field solely focused on normalizing blood sugar levels are long gone. Today, the approach in diabetology increasingly prioritizes influencing the patient's overall…
6. 11. 2020 Source: Diabetes
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Benefit of a single intra-articular injection of hyaluronic acid in the treatment of osteoarthritis

Viscosupplementation serves as a minimally invasive procedure to restore the rheological properties of synovial fluid and alleviate pain in patients with symptomatic osteoarthritis (OA). We now have…
6. 11. 2020 Source: Osteoarthritis
Injekce a biologická léčba

Efficacy and Safety of Single-Application Hyaluronic Acid in Osteoarthritis Therapy

Causal therapy for osteoarthritis does not yet exist. Patients suffering from progressive joint disease are thus dependent on symptomatic medications that alleviate symptoms and partially slow the…
6. 11. 2020 Source: Osteoarthritis
sestra podává injekci

Enoxaparin in Weight-Based Dosing for Thromboprophylaxis in Hospitalized Cancer Patients

Cancer patients are at higher risk of developing thromboembolic disease during hospitalization. Currently, there is not enough evidence supporting the efficacy and safety of the standard fixed dose…
6. 11. 2020 Source: Thromboprophylaxis

Neoadjuvant Immunotherapy in Resectable Non-Small Cell Lung Cancer

Antibodies against the programmed cell death protein 1 (PD-1) improve the survival of patients with advanced non-small cell lung cancer (NSCLC). However, their use has not yet been tested in patients…
6. 11. 2020 Source: Immunotherapy in Oncology
deprese žena vyhoření stres

Impact of Alpha-1 Antitrypsin Deficiency on Quality of Life and Mental Health of Patients

The clinical manifestation of alpha-1 antitrypsin deficiency and its impact on quality of life are highly heterogeneous. This contribution by pulmonologist Robert Sandhaus summarizes interesting…
3. 11. 2020 Source: Deficiency of Alpha-1-Antitrypsin
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