News

Neoadjuvant Immunotherapy in Resectable Non-Small Cell Lung Cancer

6. 11. 2020 Source: Immunotherapy in Oncology

Antibodies against the programmed cell death protein 1 (PD-1) improve the survival of patients with advanced non-small cell lung cancer (NSCLC). However, their use has not yet been tested in patients with resectable NSCLC. In 2018, the New England Journal of Medicine published the results of a pilot study of neoadjuvant therapy with nivolumab in patients with resectable NSCLC. Based on the promising results of this study, the investigative team subsequently decided to also test a combination of nivolumab and ipilimumab.

Impact of Alpha-1 Antitrypsin Deficiency on Quality of Life and Mental Health of Patients

The clinical manifestation of alpha-1 antitrypsin deficiency and its impact on quality of life are highly heterogeneous. This contribution by pulmonologist Robert Sandhaus summarizes interesting…

3. 11. 2020 Source: Deficiency of Alpha-1-Antitrypsin

COVID-19 and Immune Thrombocytopenic Purpura −⁠ Spanish Experience Suggests Surprising Connections

In a retrospective study examining the impact of COVID-19 on immune thrombocytopenic purpura, Spanish authors surprisingly observed a paradoxical effect.

2. 11. 2020 Source: Immune Thrombocytopenia

Care of Dental Dentures According to the Recommendations of the American Society of Dental Prosthetists

Dental dentures are the most common solution for missing teeth in the jaw. They should serve patients for several years, so proper care is essential. Therefore, dental professionals should not only…

2. 11. 2020 Source: Optimal Care of Dentures

Current Insights into the Antispasmodic and Analgesic Effects of Metamizole on the Gastrointestinal Tract

Brazilian authors published a review of available information on the mechanism of action of metamizole, its impact on gastrointestinal tract motility, its effect on the gastric mucosa, and its…

2. 11. 2020 Source: Analgesia

Impact of Thyroid Dysfunction on the Cardiovascular System in Elderly Patients

The incidence of thyroid disease increases with age. In the Czech Republic, up to 5% of the population suffers from hypothyroidism, and the prevalence of hyperthyroidism is estimated at 0.2-1%. The…

2. 11. 2020 Source: Thyroid Disorders

Rurioctocog alfa pegol in previously treated patients with severe hemophilia A: What findings did the long-term continuation study bring?

Rurioctocog alfa pegol (Adynovi) is a recombinant coagulation factor VIII modified by pegylation, which results in an approximately 1.5× prolonged biological half-life compared to standard half-life…

2. 11. 2020 Source: Hemophilia

medicina_budoucnost_krev_srazlivost_krevni_desticky

Position of aPCC in the Treatment of Hemophilia A Complicated by the Development of Inhibitors

Activated prothrombin complex concentrates (aPCC) are essential drugs that not only allow the control of bleeding in patients with congenital hemophilia A and inhibitors but also help to prevent such…

2. 11. 2020 Source: Hemophilia

Anxiety Disorders and Autoimmune Thyroiditis –⁠ A Connection Rather Than Coincidence?

Anxiolytics commonly target the central nervous system. Newly published research by Ukrainian authors offers a different perspective –⁠ according to their findings, anxiety may be related to thyroid…

29. 10. 2020 Source: Depression and Anxiety

Targeted Treatment and Quality of Life in Patients with Follicular Lymphoma

The GALLIUM clinical trial evaluated chemotherapy in combination with targeted treatment using rituximab or obinutuzumab in previously untreated patients with advanced follicular lymphoma (FL). A…

27. 10. 2020 Source: Non-Hodgkin Lymphomas and CLL

boty_nohy_chůze_běh_pohyb_sport_muž_procházka

Sport Therapy as Part of Hemophilia Management

A study by authors from the University of Wuppertal in Germany specifically examined the impact of a half-year programmed sport therapy on the subjective physical performance and quality of life of…

27. 10. 2020 Source: Hemophilia with Movement

EHL preparations have the potential to change the quality of life for people with hemophilia

Within the therapeutic modalities for hemophilia, the current era offers a number of preparations. Newer extended half-life (EHL) replacement therapies can provide hemophiliacs with better protection…

27. 10. 2020 Source: Hemophilia with Movement

Idiopathic Thrombocytopenic Purpura with SARS-CoV-2 Infection

To date, 45 cases of idiopathic (autoimmune) thrombocytopenic purpura (ITP) in individuals with confirmed SARS-CoV-2 infection have been published in the literature. In September 2020, a review…

27. 10. 2020 Source: Immune Thrombocytopenia

vysledky_lekar_cte_studie_zavery_analyza

Current Data on the Safety Profile of Baricitinib in the Treatment of Rheumatoid Arthritis

Baricitinib was approved for the treatment of rheumatoid arthritis (RA) in 2017, making it essential and relevant to monitor its safety profile in clinical practice. The analysis of data collected…

26. 10. 2020 Source: Biological Treatment

Efficacy of Baricitinib in Long-term Therapy of Rheumatoid Arthritis

Baricitinib selectively and reversibly inhibits Janus kinases JAK1 and JAK2 and is used in the treatment of adults with active rheumatoid arthritis (RA). Its safety during long-term administration…

26. 10. 2020 Source: Biological Treatment

1 … 89 90 91 92 93 … 115

Back Filter by speciality

Remove filters

Popular this week