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ADCT –⁠ a simple tool for self-diagnosis of patients with severe atopic dermatitis

1. 12. 2020 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation

Atopic dermatitis (AD) is a chronic inflammatory disease not only of childhood. It can negatively affect the quality of life despite being treatable. Control and management of the disease in different areas of life can be easily evaluated using the ADCT questionnaire.

Dupilumab in the Treatment of Adolescent Patients with Severe and Refractory Atopic Dermatitis

An open multicenter study evaluating dupilumab in the treatment of moderate to severe atopic dermatitis in adolescents confirmed its long-term efficacy and safety in this age group. In addition to…

1. 12. 2020 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation

Noonan's Syndrome –⁠ History and Present

The genetically determined syndrome linking congenital heart defect with a typical facial phenotype is named after Jacqueline Noonan, a pediatric cardiologist who practiced in the second half of the…

30. 11. 2020 Source: Growth Disorders

Register of Patients Treated with Growth Hormone (REPAR): Data Analysis as a Path to Further Optimization of Care

Treatment with recombinant growth hormone (rhGH) is available in the Czech Republic for all children meeting the indication criteria. A network of 10 centers covers the entire country, and all…

30. 11. 2020 Source: Growth Disorders

Does Ixekizumab Have Long-term Effects on Improving Psoriatic Arthritis Symptoms?

The extension of the SPIRIT-P2 study brought results of ixekizumab in patients with psoriatic arthritis (PsA) after 3 years of use. The data below were presented as a poster presentation at the…

30. 11. 2020 Source: Biological Treatment

View on the Treatment of Rheumatoid Arthritis with Baricitinib Using the NNT Indicator

Clinical parameters assessed by patients themselves are an important tool in evaluating the effectiveness of new drugs and are particularly significant in the evaluation of treatments for chronic…

30. 11. 2020 Source: Biological Treatment

Shared Decision-Making on Kidney Function Replacement

Peritoneal dialysis (PD) is not a new development, but its significance is becoming increasingly recognized. Until recently, we may not have fully appreciated its value, but in light of the global…

30. 11. 2020 Source: Chronic Kidney Disease

Options for Modifying and Improving the Efficiency of the HJHS Scoring System

The Hemophilia Joint Health Score (HJHS) is a validated tool for assessing joint health in individuals with hemophilia. Can it be modified to be used more effectively in clinical practice?

30. 11. 2020 Source: Hemophilia with Movement

Physiotherapy as Part of Comprehensive Care for People with Hemophilia –⁠ Recommendations vs. Reality

It appears that the physiotherapeutic care provided in reality to people with hemophilia does not align with current recommendations, which see it as an integral part of a multidisciplinary approach.…

30. 11. 2020 Source: Hemophilia with Movement

Use of Brodalumab in the Treatment of Severe Plaque Psoriasis −⁠ Case Report

The case report by MUDr. Jan Šternberský, Ph.D., from the Clinic of Skin and Venereal Diseases, UP Faculty of Medicine and University Hospital Olomouc, demonstrates the excellent effect of brodalumab…

28. 11. 2020 Source: Topical Treatment of Psoriasis

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Hypotension during treatment with sacubitril/valsartan: practical tips for prevention and management

Despite the undeniable benefits of sacubitril/valsartan in terms of morbidity and mortality in patients with chronic heart failure, its administration can be complicated by side effects. The most…

27. 11. 2020 Source: Chronic Heart Failure and Lipidology

Is it possible to predict survival time based on laboratory or radiological findings in patients with IPF?

High-resolution computed tomography (HRCT) imaging of the lungs is a fundamental examination in diagnosing idiopathic pulmonary fibrosis (IPF). According to experts from the Mayo Clinic, it can also…

26. 11. 2020 Source: Pulmonary Fibrosis

Gliflozins in the Treatment of Type 2 Diabetes According to Current Recommendations SVL

Gliflozins are a relatively new group of antidiabetics with a specific mechanism of action. In addition to glycemic control, they have shown favorable effects on body weight and blood pressure,…

24. 11. 2020 Source: Diabetes

Combination of Arterial Hypertension and Increased Heart Rate as a Significant Cardiovascular Risk Factor

Heart rate is one of the basic vital signs that should be regularly measured. Sinus tachycardia can be physiological under certain conditions. However, a patient with resting tachycardia should…

23. 11. 2020 Source: Cardiovascular Continuum

Is Six Months of Adjuvant Targeted Therapy Sufficient for Early Breast Cancer?

The inclusion of adjuvant targeted therapy with chemotherapy for early HER2-positive breast cancer significantly improved patient outcomes. Since 2006, based on data from registration studies, the…

23. 11. 2020 Source: Breast Carcinoma

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