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Hyaluronane in the light of new


Authors: J. Slíva
Authors‘ workplace: Přednosta: MUDr. Jiří Slíva, Ph. D ;  Ústav farmakologie 3. LF UK, Praha
Published in: Prakt. Lék. 2021; 101(5): 258-260
Category: Reviews

Overview

Hyaluronic acid (HA) has recently been mentioned very often all around us. Do we know other possible uses of HA except cosmetics? Hyaluronic acid (HA) is a natural polymer belonging to the group of hetero–polysaccharides known as glycosaminoglycans (GAG). These are naturally abundant, especially in the human vitreous, joints, umbilical cord, skin, and of course in connective tissue. We generally know that the human body contains hyaluronic acid. HA can be used in wound healing because HA can be said to de facto interfere with all key stages of the regeneration process, namely hemostasis, inflammatory response, proliferation and remodeling. Furthermore, HA is one of the most important components of the intercellular mass of connective tissue and is also significantly present in the synovial fluid. Due to its viscoelasticity, it absorbs mechanical shocks and significantly reduces friction between the joint heads. Therefore, it is offered as another possibility to use HA in a very common and painful disease – osteoarthritis.

Keywords:

osteoarthritis – Wound healing – hyaluronic acid – hemostasis – sinovial fluid – dosage forms


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