Has the time come for more personalised medicine in psychiatry?
																	
									Authors:
											C. Höschl										
				
									Authors‘ workplace:
											Ředitel: prof. MUDr. Cyril Höschl, DrSc., FRCPsych.
						; 											Psychiatrické centrum, Praha
																
				
									Published in:
					Prakt. Lék. 2010; 90(8): 502-505
					
				
									Category:
					Topic/News/Review
					
				
							
Overview
In psychiatry, personalised medicine in terms of treatment tailored to the individual patient can currently only be based on the knowledge of the mode of action of psychotropic drugs, their pharmacokinetics, and on predictive tests, e.g., QEEG methods. The use of molecular biology, genomics, and proteomics in psychiatry still lags behind other medical fields.
Key words:
 personalised medicine, psychiatry, psychopharmacology.
Sources
1. Höschl, C. First-generation antipsychotics. In: Stolerman I.P. (ed.), Encyclopaedia of Psychopharmacology. Berlin-Heidelberg: Springer-Verlag, 2010.
2. Burns, M.J. The pharmacology and toxicology of atypical antipsychotic agents. J. Toxicol. Clin. Toxicol. 2001, 39(1), p. 1-14.
3. Horáček, J. a kol. Psychotické stavy v klinické praxi. Praha: Amepra, 2003.
4. Weiden, P.J. Switching antipsychotics as a treatment strategy for antipsychotic-induced weight gain and dyslipidemia. J. Clin. Psychiatry 2007, 68, Suppl 4, p. 34-39.
5. Bareš, M., Brunovský, M., Kopeček, M et al. Changes in QEEG prefrontal cordance as a predictor of response to antidepressants in patients with treatment resistant depressive disorder: A pilot study. J. Psych. Res. 2007, 41(3-4), p. 319-325.
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
					2010 Issue 8
Most read in this issue
- Spontaneous intracranial hypotension
 - Human biomonitoring – its importance and application for evaluating population exposure to environmental chemicals (toxins)
 - Zinc and its relation to prostate tumours
 - Physical activity as a part of cardiovascular disease prevention in the general practitioner’s surgery