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Treatment of refractory overactive bladder


Authors: R. Zachoval;  V. Borovička
Authors‘ workplace: Urologické oddělení ;  Primář: doc. MUDr. Roman Zachoval, PhD. ;  Fakultní Thomayerova nemocnice, Praha
Published in: Prakt. Lék. 2010; 90(2): 102-103
Category: Case Report

Overview

This case report demonstrates the complicated management of detrusor hyperactivity in a young male with bladder outlet obstruction. After transurethral resection of the prostate and treatment using different antimuscarinics in monotherapy or in combination failed to relieve the symptoms of overactive bladder, improvement occured with a new antimuscarinic with a different type of metabolism.

Key words:
detrusor hyperactivity, bladder outlet obstruction, antimuscarinics


Sources

1. Chapple, C., van Kerrebroeck, P., Junemann, K.P., et al. Comparison of fesoterodine and tolterodine in patiens with overactive bladder. BJU Int. 2008, 102(9), p. 1128-1132.

2. De Nunzio, C., Franco, G., Rocchegiani, A. et al. The evolution of detrusor overactivity after watchful waiting, medical therapy and surgery in patiens with bladder outlet obstruction. J. Urol. 2003, 169(2), p. 535-539.

3. Irwin, D.E., Milsom I., Hunskaar S. et al. Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study. Eur. Urol. 2006, 50(6), p. 1306-1315.

4. Lemack, G.E. Defining the role of overactive bladder treatments in men with lower urinary tract symptoms. Nat. Clin. Pract. Urol. 2007, 4(4), p. 174-175.

5. Milson, I., Abrams, P., Cardozo, L. et al. How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study. BJU Int. 2001, 87(9), p. 760-766.

6. Novara, G., Galfano A., Secco S. et al. A systematic review and meta-analysis of randomized controlled trials with antimuscarinic drugs for overactive bladder. Eur. Urol. 2008, 54(4), p. 740-764.

7. Vrtal R., Vidlář A., Grepl M. a kol. Současný pohled na OAB a strategii léčby u mužů. Urologie pro praxi 2008, 9, 5, s. 236–241.

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