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Contribution of Routine Endoscopic Biopsiesof the Duodenal Mucosa to Detection of Coeliac Disease in Adults - Initial Experience


Authors: A. Albín 1;  R. Bužga 1;  J. Dvořáčková 2;  V. Šmajstrla 3
Authors‘ workplace: Interní odd. nemocnice, Vítkovice, přednosta MUDr. J. Srovnal 2NZZ Cytologická a bioptická laboratoř, Ostrava-Zábřeh 3NZZ Bormed, Ostrava-Poruba 1
Published in: Prakt. Lék. 1999; (3): 151-153
Category:

Overview

Coeliac sprue is much more frequent than formerly assumed and many patients escapediagnosis for many years. The authors used as a baseline: 1. coeliac disease (gluten enteropathy)is frequently oligosymptomatic, asymptomatic or manifested in an atypical way, 2. it occursfrequently in the population, 3. even oligosymptomatic or asymptomatic patients benefit fromtreatment (i.e. adherence to a gluten-free diet), 4. coeliac disease can be suspected fromhistological examination of the duodenal mucosa (duodenoscopy is part of gastroscopy). Basedon these assumptions it is logical to make a biopsy of the duodenal mucosa during everygastroscopic examination whatever the indication.

Key words:
coeliac disease - gluten enteropathy - histological diagnosis - endoscopic duodenalbiopsy.

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