The benefit of insulin glargine 300 U/ml for specific groups of patients in the context of available data

Czech version

Authors: Peter Novodvorský ^1,2
Authors‘ workplace: metabolické centrum s. r. o., Trenčín ¹; Department of Oncology & Metabolism, Medical School, University of Sheffield, United Kingdom ²
Published in: Diab Obez 2020; 20(39): 28-34
Category: Reviews

Overview

Potreba iniciácie terapie inzulínom v určitej fáze diabetu 2. typu (DM2T) vyplýva z patofyziológie tohoto ochorenia. Otázka správnej indikácie a načasovania inzulínoterapie pri DM2T však zostáva pomerne kontroverznou témou. Táto práca predstavuje hlavné výsledky štúdie BRIGHT a následných subanalýz BRIGHT Renal a BRIGHT Elderly a analyzuje ich význam pre správnu voľbu inzulínového preparátu pri iniciácii inzulínoterapie u pacientov s DM2T s ohľadom na ich vek a pridružené komorbidity, akými sú napr. chronická obličková choroba.

Keywords:

basal insulin – chronic kidney disease – diabetic nephropathy – elderly people with diabetes – glargine 300 U/ml – hypoglycaemia – insulin degludec – nocturnal hypoglycaemia – type 2 diabetes (DM2T)

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