50 rokov od objavu hemoglobínu HbA_1c

Czech version

Authors: Jozef Čársky
Authors‘ workplace: Ústav lekárskej chémie, biochémie a klinickej biochémie, LF UK, Bratislava
Published in: Diab Obez 2019; 19(38): 84-89

Overview

In 1968, an Iranian immunologist Samuel Rahbar published a random finding of a minor component of human hemoglobin (HbA_1c) in people with diabetes. This finding opened wide scope for research and has produced valuable results: glycohemoglobin HbA_1c has become an objective marker of long-term metabolic compensation of diabetes mellitus in clinical practice and the study of the complex glycation process of biomolecules has resulted in the identification of the molecular mechanism of the pathogenesis of chronic diabetic complications and search of the possibility for its influencing.

Keywords:

Glycation – glycohemoglobin HbA1c – patogenesis of chronic diabetic complications

Sources

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