CERAMIC ARCHITECTURES AS MODELS FOR 3D PRINTED TISSUE ENGINEERING APPLICATIONS

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Autoři: Marián Janek ^1,2; Peter Veteška ²; Kristína Randová ²; Zora Hajdúchová ²; Katarína Tomanová ^1,3; Jozef Feranc ³; Roderik Plavec ³; Leona Omaníková ³; Eva Smrčková ¹; Pavel Alexy ³; Ľuboš Bača ¹
Působiště autorů: Department of Inorganic Materials, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovakia ¹; Department of Physical and Theoretical Chemistry, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia ²; Department of Plastics, Rubber and Fibbers, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovakia ³
Vyšlo v časopise: Lékař a technika - Clinician and Technology No. 1, 2019, 49, 31-35
Kategorie: Original research

Souhrn

Shrinkage of ceramic objects produced by Fused Depositon Ceramics 3D printing technology was studied as model procedure for production of biocompatible scaffolds. The formulation of ceramic composite filament tested was based on components such as aluminium and silicium oxides and thermoplastic polymer. The resulting ceramic material after sintering is approaching the chemical composition of the mullite ceramics, which has several interesting material properties. The shrinkage of the produced testing objects was studied as function of the particle content in starting composite and sintering temperature. Observed shrinkage of the ceramic bodies produced was on the level of 17% for 65 weight % and the 23% for 40 weight % of inorganic filler content at temperature 1200 °C, respectively, with well maintained shape. The tested ceramic scaffolds were produced using slice thickness of 0.50 mm and fill gap of 0.58 mm, with regular rectilinear infill pores generated by Slic3r.

Klíčová slova:

3D printing – ceramic filament – fused deposition of ceramic – mullite – shrinkage

Zdroje

Mota C, Puppi D, Chiellini F, Chiellini E. Additive manufacturing techniques for the production of tissue engineering constructs. Journal of Tissue Engineering and Regenerative Medicine. 2012 Sep 27;9:174-90.
Hwa LC, Rajoo S, Noor AM, Ahmad N, Uday MB. Recent advances in 3D printing of porous ceramics: A review. Current Opinion in Solid State and Materials Science. 2017 Aug 20;21:323-47.
Seol YJ, Park DY, Park JY, Kim SW, Park SJ, Cho DW. A new method of fabricating robust freeform 3D ceramic scaffolds for bone tissue engineering. Biotechnology and Bioengineering. 2013 Jan 13;110:1444-55.
Corcione CE, Scalera F, Gervaso F, Montagna F, Sannino A, Maffezzoli A. One-step solvent-free process for the fabrication of high loaded PLA/HA composite filament for 3D printing. Journal of Thermal Analysis and Calorimetry. 2018 Mar 1;134:575-82.
Adel-Khattab D, Giacomini F, Gildenhaar R, Berger G, Gomes C, Linow U, Hardt M, Peleska B, Günster J, Stiller M, Houshmand A, Ghaffar KA, Gamal A, El-Mofty M, Knabe C. Development of a synthetic tissue engineered 3D printed bioceramic-based bone graft with homoge-nously distributed osteoblasts and mineralizing bone matrix in vitro. Journal of Tissue Engineering and Regenerative Medicine. 2018 Nov 9;12:44-58.
Sa MW, Nguyen BN, Moriarty RA, Kamalitdinov T, Fisher JP, Kim JY. Fabrication and evaluation of 3D printed BCP scaffolds reinforced with ZrO2 for bone tissue applications. Biotechnology and Bioengineering. 2018 Dec 5;115:989-99.
Thavornyutikarn B, Chantarapanich N, Sitthiseripratip K, Thouas GA, Chen Q. Bone tissue engineering scaffold-ing: computer-aided scaffolding techniques. Progress in Biomaterials. 2014 Jun 20;3:61-102.
Ke X, Zhang L, Yang X, Wang J, Zhuang C, Jin Z, Liu A, Zhao T, Xu S, Gao C, Gou Z, Yan G. Low‐melt bioactive glass‐reinforced 3D printing akermanite porous cages with highly improved mechanical properties for lumbar spinal fusion. Journal of Tissue Engineering and Regen-erative Medicine. 2017 Nov 27;12:1149-62.
Fielding GA, Bandyopadhyay A, Bose S. Effects of silica and zinc oxide doping on mechanical and biological properties of 3D printed tricalcium phosphate tissue engineering scaffolds. Dental Materials. 2012 Sep 16;28: 113-22.
Feng P, Wei P, Li P, Gao C, Shuai C, Peng S. Calcium silicate ceramic scaffolds toughened with hydroxyapatite whiskers for bone tissue engineering. Materials Charac-terization. 2014 Aug 20;97:47-56.
Padmanabhan SK, Gervaso F, Carrozzo M, Scalera F, Sannino A, Licciulli A. Wollastonite / hydroxyapatite scaffolds with improved mechanical, bioactive and biode-gradable properties for bone tissue engineering. Ceramics International. 2012 Jun 23;39:619-27.
Zdravkov BD, Čermák JJ, Šefara M, Janků J. Pore classification in the characterization of porous materials: A perspective. Central European Journal of Chemistry. 2007 Jan 16;5:385-95.
Solano-Umaña V, Vega-Baudrit JR. Micro, Meso and Macro Porous Materials on Medicine. Journal of Bio-materials and Nanobiotechnology. 2015 October 8;6:247-56.
Hollister SJ. Porous scaffold design for tissue engineer-ing. Nature Materials. 2005 Jul 1;4:518-24.