Vliv vaginálních globulí Melanizol^® a Klimedeks^® na hladinu glykogenu ve vaginální tkáni potkanů s experimentálně vyvolanou vaginitidou

English version

Autoři: Olena V. Dolzhykova; Ludmyla M. Maloshtan; Rimma F. Yeriomenko; Volodymyr A. Maloshtan
Vyšlo v časopise: Čes. slov. Farm., 2017; 66, 117-126
Kategorie: Původní práce

Souhrn

Experimentální studie nových vaginálních globulí Melanizol^® a Klimedeks^® byla provedena na modelu experimentální vaginitidy u potkanů vyvolané směsí terpentýnové silice a dimethylsulfoxidu. Získaná experimentální data ukazují, že vaginální globule Melanizol^® a Klimedeks^® vykazovaly 5. a 8. den experimentu významně vyšší terapeutický efekt ve srovnání s kontrolní skupinou a skupinou užívající placebo v oblasti obnovení fyziologických funkcí a kumulace glykogenu ve vaginální sliznici. Melanizol^® a Klimedeks^® překovaly v účinku referenční přípravky globule Gravagin^® a globule s Hippophaes oleum, ale byly méně účinné ve srovnání s referenčním přípravkem vaginální tablety Micogynax^® ve sledovaných kritériích.

Klíčová slova:
glykogen • vaginální pesary • vaginitita • krysa

Zdroje

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