Hypoxemia/hypoxia and new concepts of oxygen therapy in intensive care

Czech version

Authors: Jan Máca ^1,2; Marcela Káňová ^1,2; Roman Kula ^1,2; Pavel Ševčík ^1,2
Authors‘ workplace: Klinika anesteziologie, resuscitace a intenzivní medicíny LF OU a FN Ostrava ¹; Katedra intenzivní medicíny a forenzních oborů LF OU Ostrava ²
Published in: Vnitř Lék 2020; 66(2): 63-70
Category:

Overview

Oxygen is biologically vital element sustaining life. The tissue oxygen delivery is therefore precisely regulated. The degree of tissue oxygenation is estimated by measurement of oxygen blood level. The lack of oxygen on cellular and tissue level can lead to organ failure and life-threatening condition. Important adaptive processes are activated during the sublethal hypoxia with goal to preserve cellular and tissue functions. Inadequate effort to correct hypoxia can cause either disturbance of the adaptation or undesirable tissue hyperoxia. This fact is taken into account in two currently proposed concepts: (1) precise control of arterial oxemia and (2) permissive hypoxemia. Recent literature supports rather restrictive strategy of oxygen therapy in critical care.

Keywords:

cell adaptation – critical care – hypoxemia – Hypoxia – oxygen therapy

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