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proLékaře.cz / Journals / Internal Medicine / 2018 - 6

Diverticular disease: diagnosis and treatment

Czech version

Authors: Julius Špičák 1;  Miloš Kučera 2;  Gabriela Suchánková 1
Authors‘ workplace: Klinika hepatogastroenterologie IKEM, Praha 1;  Klinika transplantační chirurgie IKEM, Praha 2
Published in: Vnitř Lék 2018; 64(6): 621-634
Category: Reviews

Overview

Diverticular disease is one of the most common gastroenterological diseases. Its morphological basis are diverticula, whose prevalence in adults nears 50 %, with 25% clinical symptomatology and 5% occurrence of complications. It is a disease of older age, however its incidence is also rising in younger individuals, where it takes a more severe course. Its incidence is ascribed to a diet with a relatively low fibre content, however studies do not yield such clear results. Further risk factors include smoking, use of opiates and corticoids, obesity, alcoholism and smoking, hypertension, polycystosis, immunosuppression and use of non-steroid antiflogistics. Patients with diverticular disease also present with abnormal intestinal motility, intestinal dysbiosis and other physiological and morphological abnormalities. The most types of diverticulosis occur in the sigmoid colon, though especially in Asia the colon ascendens is more frequently affected. There are several classification schemes among which an individual assessment of complications is gaining in importance. The diagnosis includes clinical data, routine laboratory tests for inflammation, calprotectin in stool, coloscopy, ultrasound, CT and magnetic resonance. The basis for the treatment of symptomatic uncomplicated diverticular disease consists of drugs bringing symptomatic relief, fibre, probiotics, mesalazine and non-absorbable antibiotics, nonetheless the results of a number of studies are not fully convincing. The recommended treatment should be initiated with dietary fibre and probiotics, in the case of lasting problems add a non-absorbable antibiotic rifaximine with cyclic administration. Mild diverticulitis should essentially be treated by means of hydration and adjustments in the dietary regimen, antibiotics are not necessary when its course is uncomplicated and improvement is achieved, however the decision is individual and risk factors such as immunosuppression, diabetes, old age, pregnancy etc. Antibiotics are reserved for the treatment of severe or repeated diverticulitis, sepsis and complications. As prevention of further attacks, again probiotics, mesalazine and cyclically non-absorbable antibiotics are used, e,g. for a period of 10 days at monthly intervals. The proportion of surgeries is decreasing also where acute conditions are concerned and the efficiency of conservative treatment of diverticulitis is on the increase. Abscess should primarily be treated via non-surgical drainage. Even perforation and peritonitis can be treated via laparoscopic drainage without subsequent surgery being necessary, of course considering an overall condition an individual decision needs to be made. Generalized and fecal peritonitis are treated by open surgery. Earlier, elective resection was recommended after 2 attacks of diverticulitis, currently an individual approach is emphasized with respect to age, comorbidities and a character of the complaint and it is only indicated exceptionally. The proportion of laparoscopic resections is growing. The results are basically identical for Hartmann’s procedure as well as primary resection.

Key words:

calprotecin – diverticular disease – dietary fibre – diverticulosis – mesalazine – non-absorbable antibiotics – probiotics

Sources
  1. Clemens CH, Samsom M, Roelofs J et al. Colorectal visceral perception in diverticular disease. Gut 2004; 53(5): 717–722.
  2. Jung HK, Choung RS, Locke GR et al. Diarrhea-predominant irritable bowel syndrome is associated with diverticular disease? A population-based study. Am J Gastroenterol 2010; 105(3): 652–661. Dostupné z DOI: <http://dx.doi.org/10.1038/ajg.2009.621>.
  3. Peery AF, Barrett PR, Park D et al. A high-fiber diet does not protect against asymptomatic diverticulosis. Gastroenterology 2012; 142(2): 266–272. Dostupné z DOI: <http://dx.doi.org/10.1053/j.gastro.2011.10.035>.
  4. Kang JY, Hoare J, Tinto A et al. Diverticular disease of the colon – on the rise: A study of hospital admission in England between 1989/1990 and 1999/2000. Aliment Pharmacol Ther 2003; 17(9): 1189–1195.
  5. Shaheen NJ, Hansen RA, Morgan DR et al. The burden of gastrointestinal and liver diseases, 2006. Am J Gastroenterol 2006; 101(9): 2128–2138. Dostupné z DOI: <http://dx.doi.org/10.1111/j.1572–0241.2006.00723.x>.
  6. Stollman N, Raskin JB. Diverticular disease of the colon. Lancet 2004; 363(9409): 631–639. Dostupné z DOI: <http://dx.doi.org/10.1016/S0140–6736(04)15597–9>.
  7. Etzioni DA, Mack TM, Beart RW et al. Diverticulisis in the United States: 1998–2005: Changing patterns of disease and treatment. Ann Surg 2009; 249(2): 210–217. Dostupné z DOI: <http://dx.doi.org/10.1097/SLA.0b013e3181952888>.
  8. Hart AR, Kennedy HJ, Stebbings WS et al. How frequently do large bowel diverticula perforate? An incidence and cross-sectional study. Eur J Gastroenterol Hepatol 2000; 12(6): 661–665.
  9. Lamps LW, Knapple WL. Diverticular disease-associated segmental colitis. Clin Gastroenterol Hepatol 2007; 5(1): 27–31. Dostupné z DOI: <http://dx.doi.org/10.1016/j.cgh.2006.10.024>.
  10. Mulhall AM, Mahid SS, Petras RE et al. Diverticular disease associated with inflammatory bowel disease-like colitis: a systematic review. Dis Colon Rectum 2009; 52(6): 1072–1079. Dostupné z DOI: <http://dx.doi.org/10.1007/DCR.0b013e31819ef79a>.
  11. Horgan AF, McConell EJ, Wolff BD et al. Atypical diverticular disease: surgical results. Dis Colon Rectum 2001; 44(9): 1315–1318.
  12. Hinchey EJ, Schaal PGH, Richards GK. Treatment of perforated diverticular disease of the colon. Adv Surg 1978; 12: 85–109.
  13. Hansen O, Stock W. Prophylactische operation bei der divertikelkrankheit des kolons – stufenkoncept durch exakte stadienteilung. Lagenbecks Arch Chir 1999; 10(Suppl II): 1257–1260.
  14. Klarenbeek BR, de Korte N, van der Peet D et al. Review of current classifications for diverticular disease and translation into clinical practice. Int J Colorectal Dis 2012; 27(2): 207–214. Dostupné z DOI: <http://dx.doi.org/10.1007/s00384–011–1314–5>.
  15. Kruis W, Germer ChT, Leifeld L et al. Diverticular disease: guidelines of the German society for Gastroenterology, Digestive and Metabolic Diseases and the German Society for General and Visceral Surgery. Digestion 2014; 90(3): 190–207. Dostupné z DOI: <http://dx.doi.org/10.1159/000367625>.
  16. Tursi A, Brandimarte G, Di Mario F et al. Development and validation of an endoscopic classification of diverticular disease of the colon: the DICA classification. Dig Dis 2015; 33(1): 68–76. Dostupné z DOI: <http://dx.doi.org/10.1159/000366039>.
  17. Warner E, Crighton EJ, Moineddin R et al. Fourteen-year study of hospital admissions for diverticular disease in Ontario. Can J Gastroenterol 2007; 21(2): 97–99.
  18. Kang JY, Firwana B, Green AE et al. Uncomplicated diverticular disease is not a common cause of colonic symptoms. Aliment Pharmacol Ther 2011; 33(4): 487–494. Dostupné z DOI: <http://dx.doi.org/10.1111/j.1365–2036.2010.04540.x>.
  19. Painter NS, Burkitt DP. Diverticular disease of the colon: a deficiency disease of Western civilization. BMJ 1971; 2(5759): 450–454.
  20. Burkitt DP, Walker AR, Painter NS. Effect of dietary fiber on stool and the transit-times, and its role in the causation of disease. Lancet 1972; 2(7792): 1408–1412.
  21. Arora G, Mannalittara A, Mithal A et al. Concurrent conditions in patients with chronic constipation: a population-based study. PLOS One 2012; 7(10): e42910. Dostupné z DOI: <http://dx.doi.org/10.1371/journal.pone.0042910>.
  22. Peery AF, Barrett PR, Park D et al. A high-fiber diet does not protect against asymptomatic diverticulosis. Gastroenterology 2012; 142(2): 266–272. Dostupné z DOI: <http://dx.doi.org/10.1053/j.gastro.2011.10.035>.
  23. Strate LL, Liu YL, Syngal S et al. Nut, corn, and popcorn consumption and the incidence of diverticular disease. JAMA 2008; 300(8): 907–914. Dostupné z DOI: <http://dx.doi.org/10.1001/jama.300.8.907>.
  24. Crowe FL, Balkwill A, Cairns BJ et al. Source of dietary fibre and diverticular disease incidence: a prospective study of UK women. Gut 2014; 63(9): 1450–1456. Dostupné z DOI: <http://dx.doi.org/10.1136/gutjnl-2013–304644>.
  25. Hjern F, Wolk A, Hakansson N Smoking and the risk of diverticular disease in women. Br J Surg 2011; 98(8): 997–1002. Dostupné z DOI: <http://dx.doi.org/10.1002/bjs.7477>.
  26. Humes DJ, Fleming KM, Spiller RC et al. Concurrent drug use and the risk of perforated colonic diverticular disease: a population-based case-control study Gut 2011; 60(2): 219–224. Dostupné z DOI: <http://dx.doi.org/10.1136/gut.2010.217281>.
  27. Strate LL, Liu YL, Huang ES et al. Use of aspirin or nonsteroidal antiinflammatory drugs increases risk for diverticulitis and diverticular bleeding. Gastroenterology 2011; 140(5): 1427–1433. Dostupné z DOI: <http://dx.doi.org/10.1053/j.gastro.2011.02.004>.
  28. Morris CR, Harvey IM, Stebbings WS et al. Do calcium channel blockers and antimuscarinics protect against perforated colonic diverticular disease? A case control study. Gut 2003; 52(12): 1734–1737.
  29. Nagata N, Niikura R, Aoki T et al. Risk factors for adverse in-hospital outcomes in acute colonic diverticular hemorrhage. World J Gastroenterol 2015; 21(37): Dostupné z DOI: <http://dx.doi.org/10697–10703.10.3748/wjg.v21.i37.10697>.
  30. Hjern F, Wolk A, Hakansson N. Obesity, physical inactivity, and colonic diverticular disease requiring hospitalization in women: a prospective cohort study. Am J Gastroenterol 2012; 107(2): 296–302. Dostupné z DOI: <http://dx.doi.org/10.1038/ajg.2011.352>.
  31. Tennesen H, Engholm G, Moller H. Association between alcoholism and diverticulitis. Br J Surg 1999; 86(8): 1067–1068. Dostupné z DOI: <http://dx.doi.org/10.1046/j.1365–2168.1999.01171.x>.
  32. Hwang SS, Cannom RR, Abbas MA et al. Diverticulitis in transplant patients and patients on chronic corticosteroid therapy: a systematic review. Dis Colon Rectum 2010; 53(12): 1699–1707. Dostupné z DOI: <http://dx.doi.org/10.1007/DCR.0b013e3181f5643c>.
  33. Rencuzogullari A, Ozuner G, Binboga S et al. Colonic diverticulosis and diverticulitis in renal transplant recipients. Management and long-term outcomes. Ann Surg 2017; 83(3): 303–307.
  34. Bassotti G, Sietchiping-Nzepa F, De Roberto G et al. Colonic regular contractile frequency patterns in irritable bowel syndrome: the “spastic colon” revisited. Eur J Gastroenterol Hepatol 2004; 16(6): 613–617.
  35. Golder M, Burleigh DE, Belai A et al. Smooth muscle cholinergic denervation hypersensitivity in diverticular disease. Lancet 2003; 361(9373): 1945–1951. Dostupné z DOI: <http://dx.doi.org/10.1016/S0140–6736(03)13583–0>.
  36. Böttner M, Barrenschee M, Hellwig I et al. The enteric serotonergic system is altered in patients with diverticular disease. Gut 2013; 62(12): 1753–1762. Dostupné z DOI: <http://dx.doi.org/10.1136/gutjnl-2012–302660>.
  37. Bassotti G, Battaglia E, Bellone G et al. Interstitial cells of Cajal, enteric nerves, and glial cells in colonic diverticular disease. J Clin Pathol 2005; 58(9): 973–977. Dostupné z DOI: <http://dx.doi.org/10.1136/jcp.2005.026112>.
  38. Milner P, Crowe R, Kamm MA et al. Vasoactive intestinal polypeptid levels in sigmoid colon in idiopath0ic constipation and diverticular disease. Gastroenterology 1990; 99(3):666–675.
  39. Wess L, Eastwood M, Wess T et al. Cross linking of collagen is increased in colonic diverticulosis. Gut 1995; 37(1): 91–94.
  40. Meijer M, Mieremet-Ooms M, van der Zon et al. Increased matrix metalooproteinases-1, -2, -3 a -9 activity in patients with inflammatory bowel disease and the relation with Crohn disease phenotype. Dig Liver Dis 2007; 39(8): 733–739. Dostupné z DOI: <http://dx.doi.org/10.1016/j.dld.2007.05.010>.
  41. Tursi A, Papa A, Danese S et al. Review article: the pathophysiology and medici management of diverticulosis and diverticular disease of the colon. Aliment Pharmacol Ther 2015; 42(6): 664–684. Dostupné z DOI: <http://dx.doi.org/10.1111/apt.13322>.
  42. Strate L, Erichsen R, Baron J et al. Heritability and familial aggregation of diverticular disease: a population based study of twins and siblings. Gastroenterology 2013; 144(4): 736–742.e1; quiz e14. Dostupné z DOI: <http://dx.doi.org/10.1053/j.gastro.2012>.
  43. Granlund J, Svensson T, Olén O et al. The genetic influence on diverticular disease – a twin study. Aliment Pharmacol Ther 2012; 35(9): 1103–1107. Dostupné z DOI: <http://dx.doi.org/10.1111/j.1365–2036.2012.05069.x>.
  44. Conelly T, Berg A, Hegarty J et al. The TNFSF15 gene single nucleotide polymorphism rs 7848647 is associated with surgical diverticulitis. Ann Surg 2014; 259(6): 1132–1137. Dostupné z DOI: <http://dx.doi.org/10.1097/SLA.0000000000000232>.
  45. Tursi A, Brandimarte G, Giorgetti GM et al. Assessment of small intestinal bacterial overgrowth in uncomplicated acute diverticulitis of the colon. World J Gastroenterol 2005; 11(18): 2773–2776.
  46. Horgan AF, McConnell EJ, Wolff BG et al. Atypical diverticular disease: surgical results. Dis Colon Rectum 2001; 44(9): 1315–1318.
  47. Parks TG. Natural history of diverticular disease of the colon. Clin Gastroenterol 1975; 4(1): 53.
  48. De Cecco CN, Ciolina M, Annibale B et al. Prevalence and dostibution of colonic diverticula assessed with CT colonography (CTC). Eur Radiol 2016; 26(3): 639–645. Dostupné z DOI: <http://dx.doi.org/10.1007/s00330–015–3866–1>.
  49. Painter NS, Truelove SC, Ardran GM et al. Segmentation and the localization of intraluminal pressures in the human colon, with special reference to the pathogenesis of colonic diverticula. Gastroenterology 1968; 54(4): Suppl): 778–780.
  50. Sugihara K, Muto T, Morioka Y et al. Diverticular disease of the colon in Japan: A review of 615 cases. Dis Colon Rectum 1984; 27(8): S531-S537.
  51. Lohsiriwat V, Suthikeeree W. Pattern and distribution of colonic diverticulosis: Analysis of 2877 barium enemas in Thailand. World J Gastroenterol 2013; 19(46): 8709–8713. Dostupné z DOI: <http://dx.doi.org/10.3748/wjg.v19.i46.8709>.
  52. Ashktorab H, Panchal H, Shokrani B et al. Association between diverticular disease and pre-neoplastic colorectal lesions in an urban African-american population. Digestion 2015; 92(2): 60–65.
  53. Wong ER, Idris F, Chong CF et al. Diverticular disease and colorectal neoplasms: association between left sided diverticular disease with colorectal cancers and right sided with slonic polyps. Asian Pac J Cancer Prev 2016; 17(5): 2401–2405.
  54. Tursi A, Elisei W, Picchio M et al. Moderate to severe and prolonged left lower-abdominal pain is the best symptom characterizing symptomatic uncomplicated diverticular disease of the colon: comparison with fecal calprotectin in clinical setting. J Clin Gastroenterol 2015; 49(3): 218–221. Dostupné z DOI: <http://dx.doi.org/10.1097/MCG.0000000000000094>.
  55. Green BT, Rockey DC, Portwood G et al. Urgent colonoscopy for evaluation and management of acute lower gastrointestinal haemorrhage: a randomised controlled trial. Am J Gastroenterol 2005; 100(11): 2395–2402. Dostupné z DOI: <http://dx.doi.org/10.1111/j.1572–0241.2005.00306.x>.
  56. Laméris W, van Randen A, Bipat S et al. Graded compression ultrasonography and computed tomography in acute diverticulitis: Metaanalysis of the test accuracy. Eur Radiol 2008; 18(11): 2498–2511. Dostupné z DOI: <http://dx.doi.org/10.1007/s00330–008–1018–6>.
  57. Heverhagen JT, Sitter H, Zielke A et al. Prospective evaluation of the value of magnetic resonance imaging in suspected acute sigmoid diverticulitis. Dis Colon Rectum 2008; 51(12): 1810–1515. Dostupné z DOI: <http://dx.doi.org/10.1007/s10350–008–9330–4>.
  58. Saghnini E, Lahat A, Melzer E et al. Early colonoscopy in patients with acute diverticulitis. Results of a prospective pilot study. Endoscopy 2004; 36(6): 504–507. Dostupné z DOI: <http://dx.doi.org/10.1055/s-2004–814398>.
  59. Brar MS, Roxin G, Yaffe PB et al. Colonoscopy following nonoperative management of uncomplicated diverticulitis may not be warranted. Dis Colon Rectum 2013; 56(11): 1259–1264. Dostupné z DOI: <http://dx.doi.org/10.1097/DCR.0b013e3182a26bfd>.
  60. Sharma PV, Eglington T, Hider P et al. Systematic review and metaanalysis of the role of routine colonic evaluation after radiologically confirmed acute diverticulitis. Ann Surg 2014; 259(2): 263–272. Dostupné z DOI: <http://dx.doi.org/10.1097/SLA.0000000000000294>.
  61. Melchor S, Cudovic D, Jones J et al. Diagnostic and surgical management of colovesical fistulas due to sigmoid diverticulitis. J Urol 2009; 182(3): 978–982. Dostupné z DOI: <http://dx.doi.org/10.1016/j.juro.2009.05.022>.
  62. Taylor I, Duthie HL. Bran tablets and diverticular disease. Br Med J 1976; 1(6016): 988–990.
  63. Brodribb AJ. Treatment of symptomatic diverticular disease with a high-fiber diet. Lancet 1977; 1(8013): 664–666.
  64. Hodgson WJ. The placebo effect. Is it important in diverticular disease? Am J Gastroeterol 1977; 67(2): 157–162.
  65. Ornstein MH, Litlewood ER, Baird IM et al. Are fibre supplementation really necessary in diverticular disease of the colon? A controlled clinical trial. Br Med J 1981; 282(6273): 1353–1356.
  66. Smits BJ, Whitehead AM, Prescott P. Lactulose in the treatment of symptomatic diverticular disease: a comparative study with high-fiber diet. Br J Clin Pract 1990; 44(8): 314–318.
  67. Aldori VH, Giovannuci EL, Rimm EB et al. A prospective study of the diet and the risk of symptomatic diverticular disease in men. Am J Clin Nutr 1994; 60(5): 757–764. Dostupné z DOI: <http://dx.doi.org/10.1093/ajcn/60.5.757>.
  68. Tursi A. Diverticular disease: a therapeutic overview. World J gastrointest Pharmacol Ther 2010; 1(1): 27–35. Dostupné z DOI: <http://dx.doi.org/10.4292/wjgpt.v1.i1.27>.
  69. Adamová Z. Divertikulární nemoc tračníku. Rozhl Chir 2011; 90(8): 463–477.
  70. Antoš F. Divertikulární choroba tlustého střeva. 2. vyd. Avicenum: Praha 1990: 141–149. ISBN 80–201–0027-X.
  71. Hoch J. Akutní chirurgie tlustého střeva. Maxdorf: Praha 1998. ISBN 80–85800–85–3.
  72. Kazil P, Kazilová MA Divertikulární nemoc tračníku. Grada: Praha 2007. ISBN 978–80–247–1916–0.
  73. Űnlű C, Daniels L, Bart C et al. A systematic review of highe-fibre dietary therapy in diverticular disease. Int J Colorectal Dis 2012; 27(4): 419–427. Dostupné z DOI: <http://dx.doi.org/10.1007/s00384–011–1308–3>.
  74. Eisei W, Tursi A. Recent advances in the treatment of colonic diverticular disease and prevention of acute diverticulitis. Ann Gastroenterol 2016; 29(1): 24–32.
  75. Chabok A, Pahlma L, Hjem F et al. Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis. Br J Surg 2012; 99(4): 532–539. Dostupné z DOI: <http://dx.doi.org/10.1002/bjs.8688>.
  76. Daniels L, Ünlü C, de Korte N et al. Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT-proven uncomplicated acute diverticulitis. Br J Surg 2017; 104(1): 52–61. Dostupné z DOI: <http://dx.doi.org/10.1002/bjs.10309>.
  77. Űnlű C, de Korte N, Daniels I et al. A multicenter randomized clinical trial investigating the cost-effectiveness of treatment strategies with or without antibiotic for uncomplicated acute diverticulitis (DIABOLO trial). BMC Surg 2010; 10:23. Dostupné z DOI: <http://dx.doi.org/10.1186/1471–2482–10–23>.
  78. Trepsi E, Colla C, Panizza P et al. Therapeutic and prophylactic role of mesalazine (5-ASA) in symptomatic diverticular disease of the large intestine. 4 year follow-up results. Minerva Gastroenterol Dietol 1999; 45(4): 245–252.
  79. Stollman N, Magowan S, Shanahn F et al. Efficacy of delayed relapse mesalazine in the prevention of GI symptoms following acute diverticulitis: results of the DIVA trial. J Clin Gastroenterol 2013; 47(7): 621–629. Dostupné z DOI: <http://dx.doi.org/10.1097/MCG.0b013e31828003f6>.
  80. Picchio M, Elisei W, Brandimarte G et al. Mesalazine for the Treatment of Symptomatic Uncomplicated Diverticular Disease of the Colon and for Primary Prevention of Diverticulitis: A Systematic Review of Randomized Clinical Trials. See comment in PubMed Commons below. J Clin Gastroenterol. 2016; 50(Suppl 1): S64-S69. Dostupné z DOI: <http://dx.doi.org/10.1097/MCG.0000000000000669>.
  81. Raskin JB, Kamm MA, Jamal MM et al. Mesalazine did not prevent recurrent diverticulitis in phase 3 controlled trials. Gastroenterology 2014; 147(4): 793–802. Dostupné z DOI: <http://dx.doi.org/10.1053/j.gastro.2014.07.004>.
  82. Di Mario F, Aragona G, Leandro G et al. Efficacy of mesalazine in the treatment of symptomatic diverticular disease. Dig Dis Sci 2005; 50(3): 581–586.
  83. Pandolfi F, Frosali S, Petruzziello L et al. Central and muskal immunity are modified by non-absorbable antibiotic treatment in uncomplicated diverticular disease. Mini Rev Med Chem July 2015; 16(3): 218–221.
  84. Papi C, Ciaco A, Koch M et al. Efficacy of rifaximin on symptoms of uncomplicated diverticular disease of the colon. A pilot multicentre open trial. Diverticular Disease Study Group. Gastroenterol 1992; 24(8): 452–456.
  85. Papi P, Ciaco A, Koch M et al. Efficacy of rifaximin in the treatment of symptomatic diverticular disease of the colon. A multicenter double-blind placebo-controled trial. Aliment Pharmacol Ther 1995; 9(1): 33–39.
  86. Latella G, Pimpo MT, Sottili S et al. Rifaximin improves symptoms of acquired uncomplicated diverticular disease of the colon. Int J Colorectal Dis 2003; 18(1): 55–62. Dostupné z DOI: <http://dx.doi.org/10.1007/s00384–002–0396–5>.
  87. Pistoia MA, Lombardi L, Rossi M et al. Does rifaximin prevent complications of diverticular disease? A retrospective study. Eur Rev Med Pharmacol Sci 2004; 8(6): 283–287.
  88. Colecchia A, Vestito A, Pasqui F et al. Efficacy of long term cyclic administration of the poorly absorbed antibiotic Rifaximin in symptomatic, uncomplicated colonic diverticular disease. World J Gastroenterol 2007; 13(2): 264–269.
  89. D´Inca H, Pomerri F, Vettorato GM et al. Interaction between rifaximin and dietary fibre in patients with diverticular disease. Alimet Pharmacol Ther 2007; 25(7): 771–779. Dostupné z DOI: <http://dx.doi.org/10.1111/j.1365–2036.2007.03266.x>.
  90. Trivedi CD, Das KM. Emerging therapies for diverticular diseases of the colon. J Clin Gastroenterol 2008; 42(10): 1145–1151. Dostupné z DOI: <http://dx.doi.org/10.1097/MCG.0b013e318188adc1>.
  91. Bianchi M, Festa V, Moretti A et al. Meta-analysis: long-term therapy with rifaximin in the management of uncomplicated diverticular disease. Aliment Pharmacol Ther 2011; 33(8): 902–910. Dostupné z DOI: <http://dx.doi.org/10.1111/j.1365–2036.2011.04606.x>.
  92. Calanni F, Renzulli C, Fogli MV. Comment on: Rifaximin in the treatment of irritable bowel syndrome. Is there a high risk for development of antimicrobial resistance? J Clin Gastroenterol 2013; 47(9): 814–815. Dostupné z DOI: <http://dx.doi.org/10.1097/MCG.0b013e318298a32c>.
  93. Stallinger S, Eller N, Högenauer C. Non-interventional study evaluating efficacy and tolerability of rifaximin for treatment of uncomplicated diverticular disease. Wien Klin Wochenschr. 2014; 126(1–2): 9–14. Dostupné z DOI: <http://dx.doi.org/10.1007/s00508–013–0447–7>.
  94. Festa V, Spoila Alegiani S, Chiesara F et al. Retrospective comparison of long-term ten-day month rifaximin or mesalazine in prevention of relapse in acute diverticulitis. Eur Rev Med Pharmacol Sci 2017; 21(6): 1397–1404.
  95. Maconi B, Babara G, Bosetti C et al. Treatment of diverticular disease of the colon and prevention of acute diverticulitis: a systematic review. Dis Colon Rectum 2011; 54(10): 1326–1338. Dostupné z DOI: <http://dx.doi.org/10.1097/DCR.0b013e318223cb2b>.
  96. Seth A, Yan F, Polk DB et al. Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC- and MAP kinase-dependent mechanism. Am J Physiol Gastrointest Liver Physiol 2008; 294(4): G1060. Dostupné z DOI: <http://dx.doi.org/10.1152/ajpgi.00202.2007>.
  97. Yan F, Cao H, Cover TL et al. Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterology 2007; 132(2): 562. Dostupné z DOI: <http://dx.doi.org/10.1053/j.gastro.2006.11.022>.
  98. Borruel N, Carol M, Casellas F et al. Increased mucosal tumour necrosis factor alpha production in Crohn’s disease can be downregulated ex vivo by probiotic bacteria. Gut 2002; 51(5): 659.
  99. Lin YP, Thibodeaux CH, Peña JA et al. Probiotic Lactobacillus reuteri suppress proinflammatory cytokines via c-Jun. Inflamm Bowel Dis 2008; 14(8): 1068. Dostupné z DOI: <http://dx.doi.org/10.1002/ibd.20448>.
  100. Dalmasso G, Cottrez F, Imbert V et al. Saccharomyces boulardii inhibits inflammatory bowel disease by trapping T cells in mesenteric lymph nodes. Gastroenterology 2006; 131(6): 1812. Dostupné z DOI: <http://dx.doi.org/10.1053/j.gastro.2006.10.001>. Erratum in Gastroenterology 2007; 132(4): 1637.
  101. Rousseaux C, Thuru X, Gelot A et al. Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors. Nat Med 2007; 13(1): 35–37. Dostupné z DOI: <http://dx.doi.org/10.1038/nm1521>.
  102. Yan F, Polk DB. Probiotic bacterium prevents cytokine-induced apoptosis in intestinal epithelial cells. J Biol Chem 2002; 277(52): 50959–50965. Dostupné z DOI: <http://dx.doi.org/10.1074/jbc.M207050200>.
  103. Rachmilewitz D, Katakura K, Karmeli F et al. Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis. Gastroenterology 2004; 126(2): 520.
  104. Katakura K, Lee J, Rachmilewitz D et al. Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. J Clin Invest 2005; 115(3): 695. Dostupné z DOI: <http://dx.doi.org/10.1172/JCI22996>. Erratum in J Clin Invest 2005; 115(4): 1100.
  105. Yan F, Cao H, Cover TL et al. Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterology 2007; 132(2): 562. Dostupné z DOI: <http://dx.doi.org/10.1053/j.gastro.2006.11.022>.
  106. Tursi A, Brandimarte G, Giorgetti GM et al. Mesalazine and/or Lactobacillus casei in preventing recurrence of symptomatic uncomplicated diverticular disease of the colon: a prospective, randomized, open-label study. J Clin Gastroenterol 2006; 40(4): 312–316. Dostupné z DOI: <http://dx.doi.org/10.1097/01.mcg.0000210092.77296.6d>.
  107. Tursi A, Brandimarte G, Giorgetti GM et al. Balsalazide and/or high potency probiotic mixture (VSL#3) in maintaining remission after attack of acute, uncomplicated diverticulitis of the colon. Int J Colorectal Dis 2007; 22(9): 1103–1108. Dostupné z DOI: <http://dx.doi.org/10.1007/s00384–007–0299–6>.
  108. Lamiki P, Tsuchiya J, Pathak S et al. Probiotics in diverticular disease of the colon: an open label study. J Gastrointestin Liver Dis 2010; 19(1): 31–36.
  109. Tursi A, Brandimarte G, Elisei W. Randomised clinical trial: mesalazine and/or probiotics in maintaining remission of symptomatic uncomplicated diverticular disease – a double-blind, randomised, placebo-controlled study. Aliment Pharmacol Ther 2013; 38(7): 741–751. Dostupné z DOI: <http://dx.doi.org/10.1111/apt.12463>.
  110. Fric P, Zavoral M. The effect of non-pathogenic Escherichia coli in symptomatic uncomplicated diverticular disease of he colon. Eur J Gastroenterol Hepatol 2003; 15(3): 313–315. Dostupné z DOI: <http://dx.doi.org/10.1097/01.meg.0000049998.68425.e2>.
  111. Lahner E, Bellisario C, Hassan C et al. Probiotics in the Treatment of Diverticular Disease. A Systematic Review. J Gastrointestin Liver Dis 2016; 25(1): 79–86. Dostupné z DOI: <http://dx.doi.org/10.15403/jgld.2014.1121.251.srw>.
  112. De Bastiani R, Sanna G, Fracasso P et al. The management of patients with diverticulosis and diverticular disease in primary care: An online surfy among italian general practicioners. J Clin Gastroenterol 2016; 50: (Suppl 1): S89-S92. Dostupné z DOI: <http://dx.doi.org/10.1097/MCG.0000000000000580>.
  113. Tursi A, Picchio M, Elisei W et al. Current management of patients with diverticulitis and diverticular disease: a survey from the 2nd international symposium on diverticular disease. J Clin Gastroenterol 2016; 50(Suppl 1): S97-S100. Dostupné z DOI: <http://dx.doi.org/10.1097/MCG.0000000000000645>.
  114. Chappuis CW, Cohn I Jr. Acute colonic diverticulitis. Surg Clin North Am 1988; 68(2): 301–313.
  115. Biondo S, Parés D, Martí Ragué J et al. Acute colonic diverticulitis in patients under 50 years of age. Br J Surg 2002; 89(9): 1137–1141. Dostupné z DOI: <http://dx.doi.org/10.1046/j.1365–2168.2002.02195.x>.
  116. Schauer PR, Ramos R, Ghiatas AA et al. Virulent diverticular disease in young obese men. Am J Surg 1992; 164(5): 443–446; discussion 446–448.
  117. Chodak GW, Rangel DM, Passaro E Jr. Colonic diverticulitis in patients under age 40: need for earlier diagnosis. Am J Surg 1981; 141(6): 699–702.
  118. Young-Fadok T, Sgambati S, Wolff B. Increased morbidity and mortality after colectomy in patients with lupus: A case-matched series (abstract). Dis Colon Rectum 2000; 43: A57.
  119. Fischer MG, Farkas AM. Diverticulitis of the cecum and ascending colon. Dis Colon Rectum 1984; 27(7): 454–458.
  120. Markham NI, Li AK. Diverticulitis of the right colon – experience from Hong Kong. Gut 1992; 33(4): 547–549.
  121. Lo CY, Chu KW. Acute diverticulitis of the right colon. Am J Surg 1996; 171(2): 244–246. Dostupné z DOI: <http://dx.doi.org/10.1016/S0002–9610(97)89559–1>.
  122. Schultz JK, Yaqub S, Wallon C et al. Laparoscopic lavage vs. primary resection for acute perforated diverticulitis: the SCANDIV randomized clinical trial. JAMA 2015; 314(13): 1364–1375. Dostupné z DOI: <http://dx.doi.org/10.1001/jama.2015.12076>.
  123. Ambrosetti P, Chautems R, Siravia C et al. Long-term outcome of mesocolic and pelvic diverticular abscesses of the left colon: a prospective study of 73 cases. Dis Colon Rectum 2005; 48(4): 487–491. Dostupné z DOI: <http://dx.doi.org/10.1007/s10350–004–0853-z>.
  124. Siewert B, Tye G, Kruskal J et al. Impact of CT guided drainage in the treatment of diverticular abscesses: size matters. AJR Am J Roentgenol 2006; 186(3): 680–686. Dostupné z DOI: <http://dx.doi.org/10.2214/AJR.04.1708>. Erratum in AJR Am J Roentgenol 2007; 189(3): 512.
  125. Durmishi Y, Gervaz P, Brandt D et al. Results from percutaneous drainage of Hinchey stage II diverticulitis guided by computer tomography scan. Surg Endosc 2006; 20(7): 1129–1133. Dostupné z DOI: <http://dx.doi.org/10.1007/s00464–005–0574-y>.
  126. Kumar R, Kim JT, Haukoos JS et al. Factors affecting the successful management of intra-abdominal abscesses with antibiotics and the need for percutaneous drainage. Dis Colon Rectum 2006; 49(2): 183–189. Dostupné z DOI: <http://dx.doi.org/10.1007/s10350–005–0274–7>.
  127. Kronborg O. Treatment of perforated sigmoid diverticulitis: a prospective randomized trial. Br J Surg 1993; 80(4): 505–507.
  128. Zeitoun G, Laurent A, Fouffet F et al. Multicenter randomized clinical trial of primary versus secondary sigmoid resection in generalized peritonitis complicating sigmoid diverticulitis. Br J Surg 2000; 87(10): 1366–1374. Dostupné z DOI: <http://dx.doi.org/10.1046/j.1365–2168.2000.01552.x>.
  129. Saem L, Flum DR. Primary anastomosis or Hartmann´a procedure for patients with diverticular peritonitis. A systematic review. Dis Colon Rectum 2004; 47(11): 1953–1964.
  130. Constantidines VA, Tekkis PP, Athanasiou T et al. Primary resection with anastomosis vs. Hartmann procedure in nonelective surgery for acute colonic diverticulitis: a systematic review. Dis Colon Rectum 2006; 49(7): 966–981. Dostupné z DOI: <http://dx.doi.org/10.1007/s10350–006–0547–9>.
  131. Karoui M, Champault A, Pautrat K et al. Laparoscopic peritoneal lavage or primary anastomosis with defunctioning stoma for Hinchey 3 complicating diverticulitis: Results of a comparative study. Dis Colon Rectum 2009; 52(4): 609–615. Dostupné z DOI: <http://dx.doi.org/10.1007/DCR.0b013e3181a0a674>.
  132. Myers E, Hurley M, O´Sulivan GC et al. Laparoscopic peritoneal lavage for generalized peritonitis due to perforated diverticulitis. Br J Surg 2008; 95(1): 97–101. Dostupné z DOI: <http://dx.doi.org/10.1002/bjs.6024>.
  133. Swank HA, Vermeulen J, Lange JF et al. The Ladies Trial. Laparoscopic peritoneal lavage or resection for purulent peritonitis and Hartmmann´s procedure or resection with primary anastomosis for purulent or faecal peritonitis in perforated diverticulitis. BMC Surg 2010; 10: 29. Dostupné z DOI: <http://dx.doi.org/10.1186/1471–2482–10–29>.
  134. Somasekar K, Foster ME, Haray PN et al. The natural history of diverticular disease. Is here a role for elective colectomy. J R Coll Surg Eding 2002; 47(2): 481–482.
  135. Broderick-Villa G, Burchette RJ, Collins JC et al. Hospitalization for acute diverticulitis does not mandate routine elective colectomy. Arch Surg 2005; 140(6): 576–581; discussion 581–583. Dostupné z DOI: <http://dx.doi.org/10.1001/archsurg.140.6.576>.
  136. Anaya DA, Flum DR. Risk of emergency colectomy and colostomy in patients with diverticular disease. Arch Surg 2005; 242(4): 576–581; discussion 581–583.
  137. Ricciardi R, Baxter N, Read TE et al. Is the decline in the surgical treatment for diverticulitis associated with an increase in complicating diverticulitis? Dis Colon Rectum 2009; 52(9): 1558–1563. Dostupné z DOI: <http://dx.doi.org/10.1007/DCR.0b013e3181a90a5b>.
  138. Hjern J, Josephson T, Altman D et al. Outcome of younger patients with acute diverticulitis. Br J Surg 2008; 95(6): 758–764. Dostupné z DOI: <http://dx.doi.org/10.1002/bjs.6137>.
  139. Vestweber B, Vestweber KH, Paiul C et al. Single-port laparoscopic resection for diverticular disease: experiences with more than 300 consecutive patients. Surg Endosc 2016; 30(1): 50–58. Dostupné z DOI: <http://dx.doi.org/10.1007/s00464–015–4160–7>.
  140. Klarenbeek BR, Bergamaschi R, Veenhof AA et al. Laparoscopic versus open sigmoid resection for diverticular disease: folow-up assessment of the randomized control Sigma Trial. Surg Endosc 2011; 25(4): 1121–1126. Dostupné z DOI: <http://dx.doi.org/10.1007/s00464–010–1327–0>.
  141. Klarenbeek BR, Coupé VM, van der Peet D Let al. The cost effectiveness of elective laparoscopic sigmoid resection for symptomatic diverticular disease: financial outcome of the randomized control Sigma trial.. Surg Endosc 2011; 25: 776–783. Dostupné z DOI: <http://dx.doi.org/10.1007/s00464–010–1252–2>.
  142. Gervaz P, Inan I, Perneger T et al. A prospective, randomized, single-blind comparizon of laparoscopic vs. open sigmoid colectomy for diverticulitis. Ann Surg 2010; 252(1): 3–8. Dostupné z DOI: <http://dx.doi.org/10.1097/SLA.0b013e3181dbb5a5>.
  143. Purkayastha S, Constantidines VA, Tekkis PP et al. Laparoscopic vs. open resection for diverticular disease: a metaanalysis of non-randomized studies. Dis Colin Rectum 2006; 49(4): 446–463. Dostupné z DOI: <http://dx.doi.org/10.1007/s10350–005–0316–1>.
  144. Jones OM, Stevenson ARL, Clask D et al. Laparoscopic resection for diverticular disease: follow-up of 500 consecutive patients. Ann Surg 2008; 248(6): 1092–1097. Dostupné z DOI: <http://dx.doi.org/10.1097/SLA.0b013e3181884923>.
  145. Cirocchi R, Di Saverio S, Weber DG et al. Laparoscopic lavage versus surgical resection for acute diverticulitis with generalised peritonitis: a systematic review and meta-analysis. Tech Coloproctol 2017; 21(2): 93–110. Dostupné z DOI: <http://dx.doi.org/10.1007/s10151–017–1585–0>.
  146. Reissfelder C, Burh HJ, Ritz JP. What is the optimal time of surgical intervention after an acute attack of sigmoid diverticulitis: early or late elective laparoscopic resection? Dis Colon Rectum 2006; 49(12): 1842–1848. Dostupné z DOI: <http://dx.doi.org/10.1007/s10350–006–0730-z>.
  147. Thaler K, Baig MK, Berho M et al. Determinants of recurrence after sigmoid resection for uncomplicated diverticulitis. Dis Colon Rectum 2003; 46(3): 385–388. Dostupné z DOI: <http://dx.doi.org/10.1097/01.DCR.0000054638.76404.3B>.
  148. Regenbogen SE, Hardiman KM, Hendren S et al. Surgery for diverticulitis in the 21st century: a systematic review. JAMA Surg 2014; 149(3): 292–303. Dostupné z DOI: <http://dx.doi.org/10.1001/jamasurg.2013.5477>.
  149. Senft JD, Warschkow R, Diener MK et al. The transvaginal hybrid NOTES versus conventionally assisted laparoscopic sigmoid resection for diverticular disease (TRANSVERSAL) trial: study protocol or a randomized controlled trial. Trials 2014; 15: 456. Dostupné z DOI: <http://dx.doi.org/10.1186/1745–6215–15–456>.
  150. Yap FY, Omene BO, Patel MN et al. Transcatheter emboltherapy for gastrointestinal bleeding: a single center review of safety, efficacy, and clinical outcomes. Dig Dis Sci. 2013; 58(7): 1976–1984. Dostupné z DOI: <http://dx.doi.org/10.1007/s10620–012–2547-z>.
  151. Couto-Wörner I, González-Conde B, Estévez-Prieto E et al. Colonic diverticular bleeding: Urgent colonoscopy without purging and endoscopic treatment with epinephrine and hemoclips. Rev Esp Enferm Dig 2013; 105(8): 495–498.
  152. Ghassemi KA, Jensen DM. Lower GI Bleeding: Epidemiology and Management. Curr Gastroenterol Rep 2013; 15(7): 333. Dostupné z DOI: <http://dx.doi.org/10.1007/s11894–013–0333–5>.
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Diabetology Endocrinology Internal medicine
Current trends in the diagnosis and treatment of gastroesophageal reflux disease
Therapy for peptic ulcer disease
History of celiac disease
Celiac disease in 2018
Diagnosis of gastrointestinal motility disorders
Familial adenomatous polyposis: complex patient management
Conventional and biological therapy for inflammatory bowel disease
The IBD outpatient care in the clinical practice
PSC-IBD: specific phenotype of inflammatory bowel disease associated with primary sclerosing cholangitis
Possibilities of therapeutic manipulation of the gut microbiota
Prokinetics and their use in gastroenterology
Colorectal cancer screening
Therapeutic digestive endoscopy I
Therapeutic digestive endoscopy II
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