The progress of autonomic parameters in patients after myocardial infarction with ST elevation

Czech version

Authors: P. Lokaj ¹; J. Pařenica ¹; P. Kala ¹; N. Honzíková ²; R. Lábrová ¹; J. Špinar ¹
Authors‘ workplace: Interní kardiologická klinika Lékařské fakulty MU a FN Brno, pracoviště Bohunice, přednosta prof. MU Dr. Jindřich Špinar, CSc., FESC ¹; Fyziologický ústav Lékařské fakulty MU Brno, přednostka prof. MU Dr. Nataša Honzíková, CSc. ²
Published in: Vnitř Lék 2010; 56(5): 392-396
Category: Original Contributions

Overview

The patients after myocardial infarction with ST elevation (STEMI) are endangered by the development inception of autonomic dysfunction, decreased baroreflex sensitivity, decreased heart rate variability, and increased blood pressure variability as a result of increased sympathetic activity and/ or decreased parasympathetic activity. Thanks to direct angioplasty and optimal pharmacotherapy of coronary artery disease and heart failure, we didn’t found any significant changes of these parameters within a one‑year follow‑up, and mortality due to cardiac etiology was very low in this group. Autonomic dysfunction and negative left ventricular remodeling is related only to a small group of patients after STEMI, whose risk stratification will be difficult.

Key words:
myocardial infarction with ST elevation – baroreflex sensitivity – autonomic dysfunction

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