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Obesity and atherosclerosis –  what’s the link?


Authors: P. Sucharda
Authors‘ workplace: 3. interní klinika 1. lékařské fakulty UK a VFN Praha, přednosta prof. MU Dr. Štěpán Svačina, DrSc., MBA
Published in: Vnitř Lék 2010; 56(4): 289-291
Category: 11th National Diabetes Symposium "Diabetes and Angiology", Hradec Kralove, 5 to 6 June 2009

Overview

Obesity, primarily abdominal obesity, is a significant risk factor for symptomatic atherosclerosis. Atherosclerotic vascular changes and the pandemic of obesity are connected with the civilization process, in particular with diet modification and shortage of exercise and physical effort. The clinically defined metabolic syndrome is the most prominent atherosclerotic risk factor based on adipose tissue dysfunction producing low grade inflammation and endothelial dysfunction.

Key words:
obesity –  abdominal obesity –  metabolic syndrome –  adipose tissue –  atherosclerosis


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