Influence of jodine saturation on thyreopathy incidence in selected regions of the Czech Republic

Czech version

Authors: M. Dvořáková; M. Hill; J. Čeřovská; R. Bílek; P. Hoskovcová; V. Zamrazil
Authors‘ workplace: Endokrinologický ústav Praha, ředitel doc. MU Dr. Vojtěch Hainer, CSc.
Published in: Vnitř Lék 2010; 56(12): 1262-1270
Category: Celebration

Overview

Thyreopathy – a disorder of thyroid gland – is, together with diabetes, one of the most common endocrine diseases and, similarly to other endocrinopathies, higher prevalence is seen in women than in men. When eliminating iodine deficiency, it should to be taken into account that the mean ioduria in the general population reaches 100– 200 μg/ l, just 1.3% of the population does not reach ioduria of 50 μg/ l and the prevalence of goitre in school children declines below 5%. The 1991 and1997 period was a period of slight iodine deficiency (ioduria < 100 µg/ l) and was followed, between 1998 and 2006, by a period of optimum iodine saturation (ioduria > 100 µg/ l). Median ioduria observed over one year follow up differed in different age groups, highest values were seen in the 18– 35 age group and declined with age. Median iodinuria depended on the year of follow up, age and gender (p < 0.0000). Thyroid gland hypofunction was more frequent in women and ioduria levels > 100 µg/ l, thyroid gland hyperfunction was also more frequent in women but with ioduria levels < 100 µg/ l. Hypofunction, subclinical hypofunction, hyperfunction and subclinical hyperfunction were more frequent in women. Of unexplained laboratory findings, isolated hypothyroxinemia was more frequent in women and isolated hyperthyroxinemia was more frequent in men. Euthyreosis was more frequent in men than women.

Key words:
adult population – ioduria – thyreopathy – goiter

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