Extremly low SHBG level in consequence of Pro156Leu SHBG polymorphism – case reports of two women with polycystic ovary syndrome

Czech version

Authors: M. Vaňková; S. Pražáková; P. Lukášová; J. Včelák; D. Vejražková; O. Bradnová; K. Dvořáková; J. Vrbíková; B. Bendlová
Authors‘ workplace: Oddělení molekulární endokrinologie Endokrinologického ústavu Praha, ředitel doc. MU Dr. Vojtěch Hainer, CSc.
Published in: Vnitř Lék 2010; 56(12): 1292-1295
Category: Celebration

Overview

Presented case reports illustrate clinical manifestations of two women with polycystic ovary syndrome who had extremly low serum SHBG levels (Sex Hormone Binding Globulin) due to homozygote carriership of the rare Pro156Leu SHBG polymorphism.

Key words:
SHBG – polymorphism – polycystic ovary syndrome

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