Hypertension, sleep and obstructive sleep apnea

Czech version

Authors: Sovová E.1 ^,2; Marek Sova ³; M. Hobzová ³; V. Kolek ³
Authors‘ workplace: I. Interní klinika- kardiologická, Lékařská fakulta UP v Olomouci, Fakultní nemocnice Olomouc, Přednosta: doc. MUDr. Miloš Táborský, CSc., MBA. ¹; Klinika tělovýchovného lékařství a kardiovaskulární rehabilitace, Lékařská fakulta UP v Olomouci, Fakultní nemocnice Olomouc, Přednostka: doc. MUDr. Eliška Sovová, Ph. D., MBA. ²; Klinika plicních nemocí a tuberkulózy, Lékařská fakulta UP v Olomouci, Fakultní nemocnice Olomouc Přednosta: prof. MUDr. Vítězslav Kolek, DrSc. ³
Published in: Prakt. Lék. 2012; 92(6): 327-329
Category: Various Specialization

Overview

Obstructive sleep apnea (OSA) is a very common disease that carries with it a lot of risk factors that influence patient’s morbidity and mortality. Hypertension is a significant risk factor for cardiovascular diseases, and OSA is an independent risk factor for hypertension. In some patients there is a lack of night time blood pressure decrease, which can worsen their prognosis. OSA is often the cause of resistant hypertension. The treatment of OSA with a continuous positive airway pressure ventilator demonstrably improves OSA parameters but it’s impact on compensation of hypertension is controversial. In hypertensive OSA patients, the increase of plasmatic aldosterone level is common and it is likely that these patients could benefit from pharmacological treatment with spironolactone.

Key words:
Obstructive sleep apnea, hypertension, continuous airway pressure

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