Biological therapy in oncology (I)
Authors:
P. Králíčková; J. Krejsek; I. Krčmová
Authors‘ workplace:
ÚSTAV KLINICKÉ IMUNOLOGIE A ALERGOLOGIE
; Fakultní nemocnice Hradec Králové
Published in:
Prakt. Lék. 2011; 91(4): 189-192
Category:
Reviews
Overview
The incidence of cancer increased substantially during the 20th century. Cancer is the second leading cause of mortality in developed countries. Partially effective therapeutic approaches and medicamentous treatments:
– irradiation,
– chemotherapy, and
– later biological therapy
were developed in the second half of the last century to help combat this cancer epidemic. We review the efficacy of biological therapy based on cell-mediated immunity (BCG vaccination, cancer vaccination, adoptive immunotherapy).
The aim of biological therapy is to optimally target the tumorigenesis process and to reverse it with minimal side effects.
Key words:
biological treatment, bacterial adjuvants, cancer vaccination, adoptive immunotherapy.
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