New approaches to heart valve diseases in experimental and clinical cardiology

Czech version

Authors: J. Šochman ¹; J. H. Peregrin ²
Authors‘ workplace: Klinika kardiologie IKEM Přednosta: prof. MUDr. J. Kautzner, CSc. ¹; Základna radiodiagnostiky a intervenční radiologie Přednosta: doc. MUDr. J. H. Peregrin, CSc. Institut klinické a experimentální medicíny, Praha Ředitel: MUDr. Štefan Vítko, CSc. ²
Published in: Prakt. Lék. 2006; 86(11): 635-642
Category: Of different specialties

Overview

There has been a clear increase in the number of techniques in animal experiments dealing with various approaches to nonsurgical modification of heart valve diseases. It is also evident that some of the methods have already been put to use in clinical practice. This paper presents an overview of various options of the handling this issue and provides some morphological observations. It seems it is still too early to evaluate the different methods intended for a permanent solution to various cardiac valve defects. This is because relatively few procedures have been performed to date and, more importantly, nothing is known about the durability of the procedures. In addition, the standard of current cardiac surgery is very high. Still, it is quite easy to accept the idea for temporary catheter-based treatment of types of diseases currently not eligible for surgery, or in cases where surgery would be associated with unacceptably high risk.

Key words:
experimental methods, heart valve diseases, nonsurgical techniques