#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Biochemical molecular mechanisms of heart failure


Authors: J. Masopust
Authors‘ workplace: Univerzita Karlova v Praze, 2. lékařská fakulta, Ústav klinické biochemie a patobiochemie Přednosta: doc. MUDr. Richard
Published in: Prakt. Lék. 2006; 86(11): 631-635
Category: Various Specialization

Overview

In the articel, the author presents recent findings in the field of molecular genetics concerning the regulation of foetal development of the heart and its function after birth and in adulthood. In particular, reference is made to the importance of molecular regulation of calcium channel function, the beta-adrenergic system and natriuretic factors in the development of pathological hypertrophy of heart. The role of mutations in the genes for contractile and structural proteins in the pathogenesis of hypertrophic and dilated cardiomyopathy is described, and the association of gene alterations and cardiac arrhythmias is discussed.

Key words:
molecular genetics, heart development, cardiac hypertrophy, heart failure, cardiac arrhythmias


Labels
General practitioner for children and adolescents General practitioner for adults

Article was published in

General Practitioner

Issue 11

2006 Issue 11

Most read in this issue
Topics Journals
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#