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The power network frequency magnetic sinusoidal field and tumors of the head and throat


Authors: A. Čoček 1;  A. Jandová 2;  J. Pokorný 2;  A. Dohnalová 3;  M. Ambruš 4;  A. Hahn 1
Authors‘ workplace: ORL klinika 3. LF UK a FN KV, Praha přednosta doc. MUDr. Dr. med. A. Hahn, CSc. 1;  Ústav radiotechniky a elektroniky AV, Praha, ředitel ing. V. Matějec 2;  Fyziologický ústav 1. LF UK, Praha, přednosta prof. O. Kittnar, DrSc. 3;  Klinika radioterapie a onkologie 3. LF UK a FNKV, Praha přednostka MUDr. M. Kubecová 4
Published in: Prakt. Lék. 2005; 85(12): 690-691
Category: Of different specialties

Overview

Prior to treatment, we have sampled blood from 60 patients suffering carcinoma of the larynx and pharynx. CD4 lymphocytes were separated from the blood. We have followed up their capacity of surface adherence depending on the presence of antigen (leucocyte adherence inhibition assay). As antigen there served a specific antigen prepared from the corresponding tumor tissue (mitochondrial antigen of the tumor cell) and a nonspecific antigen prepared from the serum of inbred C3H/H2K strain mice infected with LDH virus (capsid antigen). The results were evaluated with the aid of the non-adherence index (NAI). The experiment was repeated under exposure of the substrate to a magnetic sinusoid field (MSF) of power frequency at an induction of 1 and 10 mT. The results were evaluated in like manner and compared through the t-test for two independent series. Results of the measurings showed that CD4 lymphocytes obtained from the blood of patientssuffering carcinomas of the larynx and of the pharynx, as compared to CD4 lymphocytes of healthy subjects, have a decreased capacity of surface adherence (higher NAI values). Upon exposure to MSF of power network frequency their capacity to adhere increased to a statistically significant degree. On presumption that the adherence capacity of lymphocytes is a manifestation of cell-mediated immunity (CMI), it can be stated that MSF influences CMI in a positive sense, namely in the case of MSF of power network frequency at an induction of 1 and 10 mT.

Key words:
carcinoma of the larynx and pharynx – magnetic sinusoid field – leucocyte adherence inhibition assay.


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