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Iron deficiency in pediatric patients with congenital heart defects


Authors: S. Kaprálová;  B. Ludíková;  E. Klásková;  A. Palátová
Authors‘ workplace: Dětská klinika Fakultní nemocnice a Lékařské fakulty Univerzity Palackého, Olomouc
Published in: Čes-slov Pediat 2021; 76 (6): 330-334.
Category: Review

Overview

Care for patients with congenital heart defects should be comprehensive and targeted not only to the defect itself but also to the diverse range of associated diagnoses that can fundamentally affect morbidity and mortality. Iron deficiency anaemia is an affiliated serious diagnosis that exacerbates tissue hypoxia in patients with cyanotic heart defects and contributes to the development of heart failure in defects with significant left-to-right shunt.

The authors present a brief overview article on this issue.

Keywords:

Iron deficiency anemia – Iron deficiency – congenital heart defects with left-to-right shunt – cyanotic congenital heart defects


Sources

1. van der Linde D, Konings E, Slager M, et al. Birth prevalence of congenital heart disease worldwide. J Am Coll Cardiol 2011; 58 (21): 2241–2247.

2. Šamánek M, Voříšková M. Congenital heart disease among 815,569 children born between 1980 and 1990 and their 15-year survival: a prospective Bohemia survival study. Pediatr Cardiol 1999 Nov-Dec; 20 (6): 411–417.

3. Chaloupecký V, et al. Dětská kardiologie. 1. vyd. Praha: Galén, 2006: 1–437.

4. Carson JA, Duff A, Poses RM, et al. Effect of anemia and cardiovascular disease on surgical mortality and morbidity. Lancet 1996; 348: 1055–1060.

5. Wang M. Iron deficiency and other types of anemia in infants and children. Am Fam Physician 2016; 93 (4): 270–278.

6. Lebl J, et al. Klinická pediatrie. 2. vyd. Praha: Galén, 2014: 1–698.

7. Pospíšilová D. Sideropenická anémie v dětském věku. Pediatr Praxi 2001; 6: 269–273.

8. Lopez A, Cacoub P, Macdougall IC, Peyrin-Biroulet L. Iron deficiency anaemia. Lancet 2016; 27: 907–916.

9. Tsintoni A, Dimitriou G, Karatza AA. Nutrition of neonates with congenital heart disease: existing evidence, conflicts and concerns. J Matern Fetal Neonatal Med 2020; 33: 2487–2492.

10. Puri K, Price JF, Spinner JA, et al. Iron deficiency is associated with adverse outcomes in pediatric heart failure. J Pediatr 2020; 216: 58–66.

11. Zabala LM, Guzzetta N. Cyanotic congenital heart disease (CCHD): focus on hypoxemia, secondary erythrocytosis, and coagulation alterations. Paediatr Anaesth 2015; 25: 981–989.

12. Jansa P. Plicní arteriální hypertenze u vrozených srdečních vad. Interní Med 2006; 6: 266–269.

13. Olcay L, Ozer S, Gurgey A, et al. Parameters of iron deficiency in children with cyanotic congenital heart disease. Pediatr Cardiol 1996; 17: 150–154.

14. Terlemez S, Tunaoğlu FS, Göktaş T, et al. The effects of iron treatment on viscosity in children with cyanotic congenital heart disease. Hematology 2017; 22: 30–35.

15. Itiola AY, Animasahun BA, Njokanma OF. Serum iron status of children with cyanotic congenital heart disease in Lagos, Nigeria. Sultan Qaboos Univ Med J 2019; 19: 345–351.

16. Onur CB, Sipahi T, Tavil B, et al. Diagnosis iron deficiency in cyanotic heart disease. Indian J Pediatr 2003; 70: 29–31.

17. Martinez-Quintana E, Rodriguez-Gonzalez F. Iron deficiency anemia detection from hematology parameters in adult congenital heart disease patients. Congenit Heart Dis 2013; 8: 117–123.

18. Kaemmerer H, Fratz S, Braun SL. Erythrocyte indexes, iron metabolism, and hyperhomocysteinemia in adults with cyanotic congenital cardiac disease. Am J Cardiol 2004; 94: 825–828.

19. Blanche C, Alonso-Gonzalez R, Uribarri A, et al. Use of intravenous iron in cyanotic patients with congenital heart disease and/or pulmonary hypertension. Int J Cardiol 2018; 15: 79–83.

20. Tay EL, Peset A, Papaphylactou M, et al. Replacement therapy for iron deficiency improves exercise capacity and quality of life in patients with cyanotic congenital heart disease and/or the Eisenmenger syndrome. Int J Cardiol 2011; 15: 301–312.

21. Broberg CS. Challenges and management issues in adults with cyanotic congenital heart disease. Heart 2016; 102: 720–725.

22. Hentze MW, Muckenthaler MU, Galy B, Camaschella C. Two to tango: regulation of Mammalian iron metabolism. Cell 2010; 142: 24–38.

Labels
Neonatology Paediatrics General practitioner for children and adolescents

Article was published in

Czech-Slovak Pediatrics

Issue 6

2021 Issue 6

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